- Cardiac Health and Mental Health
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiovascular and exercise physiology
- Lipoproteins and Cardiovascular Health
- Health Systems, Economic Evaluations, Quality of Life
- Diet and metabolism studies
- Heart Rate Variability and Autonomic Control
- Blood Pressure and Hypertension Studies
- Diabetes Management and Research
- Diabetes Treatment and Management
- Cardiovascular Health and Risk Factors
- Stroke Rehabilitation and Recovery
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Smoking Behavior and Cessation
- GDF15 and Related Biomarkers
- Nutritional Studies and Diet
- Antiplatelet Therapy and Cardiovascular Diseases
- Metabolism, Diabetes, and Cancer
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Nutrition and Health in Aging
- Cardiac electrophysiology and arrhythmias
Lund University
2016-2025
Skåne University Hospital
2016-2025
Malmö University
2006-2025
Getinge (Sweden)
2021
Ericsson (Sweden)
2021
Brigham and Women's Hospital
2017
Odense University Hospital
2017
Departamento de Epidemiología
2012
National University Hospital of Iceland
2006
Journal Article Corrected proof Guidelines 2023 ESC for the management of acute coronary syndromes: Developed by task force on syndromes European Society Cardiology (ESC) Get access Robert A Byrne, Byrne (Ireland) Corresponding authors: A. Department and Cardiovascular Research Institute (CVRI) Dublin, Mater Private Network, Ireland, School Pharmacy Biomolecular Sciences, RCSI University Medicine Health Ireland. Tel: +353-1-2483190, E-mail: robertabyrne@rcsi.ie...
Abstract Aims Improved dietary habits are important for successful secondary prevention after myocardial infarction (MI), with counselling and support on healthy constituting a cornerstone of cardiac rehabilitation (CR). However, there is limited knowledge how to optimize CR organization motivate patients adopt habits. We aimed explore associations between programme structure, processes, self-reported 1 year post-MI. Methods results Organizational data from 73 Swedish centres patient-level...
Clinical trials have demonstrated that a reduction in low-density lipoprotein cholesterol (LDL-C) reduces cardiovascular (CV) events. This has, however, not yet been shown real-world setting. We aimed to investigate the association between LDL-C changes and statin intensity with prognosis after myocardial infarction (MI).Patients admitted MI were followed for mortality major CV Changes 6- 10-week follow-up visit analysed. The associations quartiles of change outcomes assessed using adjusted...
Understanding the genetic architecture of cardiac structure and function may help to prevent treat heart disease. This investigation sought identify common variations associated with inter-individual variability in function.
Abstract Aims To estimate the proportion of patients with a recent myocardial infarction (MI) who would be eligible for additional lipid-lowering therapy according to 2019 European Society Cardiology (ESC)/European Atherosclerosis (EAS) guidelines management dyslipidaemias, and simulate effects expanded on attainment low-density lipoprotein cholesterol (LDL-C) target as recommended by guidelines. Methods results Using nationwide SWEDEHEART register, we included 25 466 had attended follow-up...
This study sought to identify homogenous echocardiographic phenotypes in community-based cohorts and assess their association with outcomes.Asymptomatic cardiac dysfunction leads a high risk of long-term cardiovascular morbidity mortality; however, better classification asymptomatic individuals remains challenge.Echocardiographic were identified using K-means clustering the first generation STANISLAS (Yearly non-invasive follow-up Health status Lorraine insured inhabitants) cohort (N = 827;...
Abstract ESC Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible practices to be followed, however, particularly in low-resource settings. To address this issue, a set of guideline-related documents were created identify key priorities users these The highlight the related describe strategies clinicians approach implementation or discuss alternatives which are line intention...
Combination lipid-lowering therapy (LLT) after myocardial infarction (MI) achieves lower low-density lipoprotein cholesterol (LDL-C) levels and better cardiovascular outcomes vs statin monotherapy. As a result, global guidelines recommend LDL-C but, paradoxically, advise treatment through stepwise approach. Yet the need for combination is inevitable as <20% of patients achieve goals with statins alone. Whether combining ezetimibe early late MI results in unknown. In this study, authors...
Abstract Aims Participation in exercise-based cardiac rehabilitation (exCR) increases aerobic capacity and improves outcomes patients following myocardial infarction (MI) is therefore universally recommended. While meta-analyses consistently report that participation exCR reduces cardiovascular mortality, there are conflicting results regarding effects on total mortality. Presently, many eligible do not receive clinical practice. We aimed to investigate the relation between post-MI mortality...
Background A significant proportion of patients with ST-segment-elevation myocardial infarction (MI) have no standard modifiable cardiovascular risk factors (SMuRFs) and unexpected worse 30-day outcomes compared those SMuRFs. The aim this article is to examine non-ST-segment-elevation MI in the absence Methods Results Presenting features, management, without SmuRFs (hypertension, diabetes, hypercholesterolemia, smoking) were Swedish registry SWEDEHEART (Swedish Web-System for Enhancement...
Non-high-density lipoprotein cholesterol (HDL-C) provides an estimate of lipid-associated risk and is a secondary treatment target after myocardial infarction (MI). The aim was to study the relationship between non-HDL-C levels MI adverse outcomes.
While patient performance after participating in cardiac rehabilitation programmes acute myocardial infarction is regularly reported through registry and survey data, information on programme characteristics less well described.The aim of this study was to evaluate Swedish adherence European Guidelines Cardiovascular Disease Prevention.Cardiac at all 78 centres Sweden 2016 were surveyed using a web-based questionnaire (100% response rate). The questions based core components as recommended...
Despite its well-established positive effects, exercise-based cardiac rehabilitation (exCR) is underused in patients following an acute myocardial infarction (AMI). The aim of the study was to identify factors associated with non-attendance at exCR post-AMI a large Swedish cohort. A total 31,297 who have suffered AMI, mean age 62.4 ± 4 years, were included from SWEDEHEART registry during years 2010-2016. Comparisons between attenders and non-attenders done baseline for variables: age, sex,...
Abstract Aims The quality registry SWEDEHEART covers data across the patient pathway after an acute myocardial infarction (MI), from hospital care to secondary prevention. Although cardiac rehabilitation (CR) is strongly recommended MI, there still heterogeneity regarding standards, uptake, and adherence rates. aim of SWEDEHEART-CR provide continuous information on prevention CR performance support audit development evidence-based practice. To facilitate improvement research initiatives, a...
The incidence of atherosclerotic cardiovascular disease increases with levels low-density lipoprotein cholesterol (LDL-C). Yet, a paradox may exist where lower LDL-C at myocardial infarction (MI) are associated poorer prognoses.To assess the association between MI risk factor burden and cause-specific outcomes.Statin-naive patients hospitalized for first registered in SWEDEHEART were included. Data linked to Swedish registers. Primary outcomes all-cause mortality nonfatal MI. Associations...
Objectives The objective of this study was to assess the completeness registration secondary preventive variables comparing on-site visits with telephone consultations during follow-up after myocardial infarction. Design This an observational based on Swedish quality registry SWEDEHEART. Setting and outcome measures We analysed proportion missing values for major target data registered at 2-month 1-year visits, 2006–2022 (n=101 199). χ 2 tests were used compare differences in consultations....
Participation in exercise-based cardiac rehabilitation (EBCR) improves long-term prognosis for patients following myocardial infarction (MI). Evaluating the effects of EBCR is challenging due to voluntary nature participation program. Using register data on 18,978 hospitalized MI 2011 2013 Sweden, a non-experimental study design employed evaluate health-related quality life (HRQoL). Conditional independence from non-random treatment assignment considered through set potential-outcome (PO)...
Abstract Background Closing the evidence-practice gap for treatment of acute coronary syndrome (ACS) is central to improving quality care. Under European Society Cardiology (ESC) framework, we aimed develop updated indicators (QIs) evaluation care and outcomes patients with ACS. Methods A Working Group experts including members ESC Clinical Practice Guidelines Task Force ACS, Acute CardioVascular Care Association Percutaneous Cardiovascular Interventions followed methodology QI development....
Abstract Background Cardiac telerehabilitation addresses common barriers for attendance at exercise-based cardiac rehabilitation (EBCR). Pragmatic real-world studies are however lacking, limiting generalisability of available evidence. We aimed to evaluate feasibility, safety, and patient perceptions remotely delivered EBCR in a multicentre clinical practice setting after myocardial infarction (MI). Methods This study included 232 post-MI patients (63.7 years, 77.5% men) from 23 centres...
Stroke and acute myocardial infarction (AMI) rank among the leading causes of mortality. Physical activity exercise are recommended as part rehabilitation after AMI to prevent cardiovascular events, but importance for stroke prevention has not been investigated using population-based data. To determine associations between participation in exercise-based cardiac (EBCR) self-reported physical with risk total stroke, ischemic intracerebral hemorrhage AMI. This was a nationwide, double cohort...