Margrét Leósdóttir

ORCID: 0000-0003-1677-1566
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About
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Research Areas
  • Cardiac Health and Mental Health
  • Acute Myocardial Infarction Research
  • Cardiovascular Function and Risk Factors
  • Heart Failure Treatment and Management
  • Cardiac Imaging and Diagnostics
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiovascular and exercise physiology
  • Lipoproteins and Cardiovascular Health
  • Health Systems, Economic Evaluations, Quality of Life
  • Diet and metabolism studies
  • Heart Rate Variability and Autonomic Control
  • Blood Pressure and Hypertension Studies
  • Diabetes Management and Research
  • Diabetes Treatment and Management
  • Cardiovascular Health and Risk Factors
  • Stroke Rehabilitation and Recovery
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Smoking Behavior and Cessation
  • GDF15 and Related Biomarkers
  • Nutritional Studies and Diet
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Metabolism, Diabetes, and Cancer
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Nutrition and Health in Aging
  • Cardiac electrophysiology and arrhythmias

Lund University
2016-2025

Skåne University Hospital
2016-2025

Malmö University
2006-2025

Getinge (Sweden)
2021

Ericsson (Sweden)
2021

Brigham and Women's Hospital
2017

Odense University Hospital
2017

Departamento de Epidemiología
2012

National University Hospital of Iceland
2006

Robert A. Byrne Xavier Rosselló J J Coughlan Emanuele Barbato Colin Berry and 95 more Alaide Chieffo Marc J. Claeys Gheorghe‐Andrei Dan Marc R. Dweck Mary Galbraith Martine Gilard Lynne Hinterbuchner Ewa A. Jankowska Peter Jüni Takeshi Kimura Vijay Kunadian Margrét Leósdóttir Roberto Lorusso Roberto F.E. Pedretti Angelos G. Rigopoulos María Rubini Giménez Hölger Thiele Pascal Vranckx Sven Waßmann Nanette K. Wenger Borja Ibáñez Sigrun Halvorsen Stefan James Magdy Abdelhamid Victor Aboyans Nina Ajmone Marsan Sotiris Antoniou Riccardo Asteggiano Maria Bäck Davide Capodanno Rubén Casado-Arroyo Salvatore Cassese Jelena Čelutkienė Maja Čikeš Jean‐Philippe Collet Grégory Ducrocq Volkmar Falk Laurent Fauchier Tobias Geisler Diana A. Gorog Lene Holmvang Tiny Jaarsma Hywel Wynne Jones Lars Køber Konstantinos C. Koskinas Dipak Kotecha Konstantin A. Krychtiuk Ulf Landmesser George Lazaros Basil S. Lewis Bertil Lindahl Aleš Linhart Maja‐Lisa Løchen Mamas A. Mamas John W. McEvoy Borislava Mihaylova Richard Mindham Christian Mueller Lis Neubeck Josef Niebauer Jens Cosedis Nielsen Alexander Niessner Valeria Paradies Agnès Pasquet Steffen E. Petersen Eva Prescott Amina Rakisheva Bianca Rocca Giuseppe Rosano Leyla Elif Sade François Schiele Jolanta M. Siller‐Matula Christian Sticherling Robert F. Storey Matthias Thielmann Christiaan Vrints Stephan Windecker Rune Wiseth Adam Witkowski Mohammed El Amine Bouzid Hamlet Hayrapetyan Bernhard Metzler Patrizio Lancellotti Mugdim Bajrić Kiril Karamfiloff Andreas Mitsis Petr Ošťádal Rikke Sørensen Tamer Elwasify Toomas Marandi Essi Ryödi Jean‐Philippe Collet Archil Chukhrukidze Julinda Mehilli Periklis Davlouros

10.1093/eurheartj/ehad191 article EN European Heart Journal 2023-08-25
Robert A. Byrne Xavier Rosselló J J Coughlan Emanuele Barbato Colin Berry and 95 more Alaide Chieffo Marc J. Claeys Gheorghe‐Andrei Dan Marc R. Dweck Mary Galbraith Martine Gilard Lynne Hinterbuchner Ewa A. Jankowska Peter Jüni Takeshi Kimura Vijay Kunadian Margrét Leósdóttir Roberto Lorusso Roberto F.E. Pedretti Angelos G. Rigopoulos María Rubini Giménez Hölger Thiele Pascal Vranckx Sven Waßmann Nanette K. Wenger Borja Ibáñez Sigrun Halvorsen Stefan James Magdy Abdelhamid Victor Aboyans Nina Ajmone Marsan Sotiris Antoniou Riccardo Asteggiano Maria Bäck Davide Capodanno Rubén Casado-Arroyo Salvatore Cassese Jelena Čelutkienė Maja Čikeš Jean‐Philippe Collet Grégory Ducrocq Volkmar Falk Laurent Fauchier Tobias Geisler Diana A. Gorog Lene Holmvang Tiny Jaarsma Hywel Wynne Jones Lars Køber Konstantinos C. Koskinas Dipak Kotecha Konstantin A. Krychtiuk Ulf Landmesser George Lazaros Basil S. Lewis Bertil Lindahl Aleš Linhart Maja‐Lisa Løchen Mamas A. Mamas John W. McEvoy Borislava Mihaylova Richard Mindham Christian Mueller Lis Neubeck Josef Niebauer Jens Cosedis Nielsen Alexander Niessner Valeria Paradies Agnès Pasquet Steffen E. Petersen Eva Prescott Amina Rakisheva Bianca Rocca Giuseppe Rosano Leyla Elif Sade François Schiele Jolanta M. Siller‐Matula Christian Sticherling Robert F. Storey Matthias Thielmann Christiaan Vrints Stephan Windecker Rune Wiseth Adam Witkowski Mohammed El Amine Bouzid Hamlet Hayrapetyan Bernhard Metzler Patrizio Lancellotti Mugdim Bajrić Kiril Karamfiloff Andreas Mitsis Petr Ošťádal Rikke Sørensen Tamer Elwasify Toomas Marandi Essi Ryödi Jean‐Philippe Collet Archil Chukhrukidze Julinda Mehilli Periklis Davlouros

Journal Article Corrected proof Guidelines 2023 ESC for the management of acute coronary syndromes: Developed by task force on syndromes European Society Cardiology (ESC) Get access Robert A Byrne, Byrne (Ireland) Corresponding authors: A. Department and Cardiovascular Research Institute (CVRI) Dublin, Mater Private Network, Ireland, School Pharmacy Biomolecular Sciences, RCSI University Medicine Health Ireland. Tel: +353-1-2483190, E-mail: robertabyrne@rcsi.ie...

10.1093/ehjacc/zuad107 article EN European Heart Journal Acute Cardiovascular Care 2023-09-22

Abstract Aims Improved dietary habits are important for successful secondary prevention after myocardial infarction (MI), with counselling and support on healthy constituting a cornerstone of cardiac rehabilitation (CR). However, there is limited knowledge how to optimize CR organization motivate patients adopt habits. We aimed explore associations between programme structure, processes, self-reported 1 year post-MI. Methods results Organizational data from 73 Swedish centres patient-level...

10.1093/eurjcn/zvae147 article EN cc-by European Journal of Cardiovascular Nursing 2025-01-02

Clinical trials have demonstrated that a reduction in low-density lipoprotein cholesterol (LDL-C) reduces cardiovascular (CV) events. This has, however, not yet been shown real-world setting. We aimed to investigate the association between LDL-C changes and statin intensity with prognosis after myocardial infarction (MI).Patients admitted MI were followed for mortality major CV Changes 6- 10-week follow-up visit analysed. The associations quartiles of change outcomes assessed using adjusted...

10.1093/eurheartj/ehaa1011 article EN cc-by-nc European Heart Journal 2020-11-27
Philipp S. Wild Janine F. Felix Arne Schillert Alexander Teumer Ming‐Huei Chen and 95 more Maarten J.G. Leening Uwe Völker Vera Großmann Jennifer A. Brody Marguerite R. Irvin Sanjiv J. Shah Setia Pramana Wolfgang Lieb Reinhold Schmidt Alice Stanton Dörthe Malzahn Albert V. Smith Johan Sundström Cosetta Minelli Daniela Ruggiero Leo‐Pekka Lyytikäinen Daniel Tiller J. G. Smith Claire Monnereau Marco R. Di Tullio Solomon K. Musani Alanna C. Morrison Tune H. Pers Michael P. Morley Marcus E. Kleber Jayashri Aragam Emelia J. Benjamin Joshua C. Bis Egbert Bisping Ulrich Broeckel Susan Cheng Jaap W. Deckers Fabiola Del Greco M Frank Edelmann Myriam Fornage Lude Franke Nele Friedrich Tamara B. Harris Edith Hofer Albert Hofman Jie Huang Alun D. Hughes Mika Kähönen KNHI investigators Jochen Kruppa Karl J. Lackner Lars Lannfelt Rafael Laskowski Lenore J. Launer Margrét Leósdóttir Honghuang Lin Cecilia M. Lindgren Christina Loley Calum A. MacRae Deborah Mascalzoni Jamil Mayet Daniel Medenwald Andrew P. Morris Christian Müller Martina Müller‐Nurasyid Stefania Nappo Peter M. Nilsson Sebastian Nuding Teresa Nutile Annette Peters Arne Pfeufer Diana Pietzner Peter P. Pramstaller Olli T. Raitakari Kenneth Rice Fernando Rivadeneira Jerome I. Rotter Saku Ruohonen Ralph L. Sacco Tandaw E. Samdarshi Helena Schmidt Andrew Sharp Denis C. Shields Rossella Sorice Nona Sotoodehnia Bruno H. Stricker Praveen Surendran Simon Thom Anna Maria Töglhofer André G. Uitterlinden Rolf Wachter Henry Völzke Andreas Ziegler Thomas Münzel Winfried März Thomas P. Cappola Joel N. Hirschhorn Gary F. Mitchell Nicholas L. Smith Ervin R. Fox

Understanding the genetic architecture of cardiac structure and function may help to prevent treat heart disease. This investigation sought identify common variations associated with inter-individual variability in function.

10.1172/jci84840 article EN Journal of Clinical Investigation 2017-04-09

Abstract Aims To estimate the proportion of patients with a recent myocardial infarction (MI) who would be eligible for additional lipid-lowering therapy according to 2019 European Society Cardiology (ESC)/European Atherosclerosis (EAS) guidelines management dyslipidaemias, and simulate effects expanded on attainment low-density lipoprotein cholesterol (LDL-C) target as recommended by guidelines. Methods results Using nationwide SWEDEHEART register, we included 25 466 had attended follow-up...

10.1093/eurheartj/ehaa034 article EN cc-by-nc European Heart Journal 2020-01-24

This study sought to identify homogenous echocardiographic phenotypes in community-based cohorts and assess their association with outcomes.Asymptomatic cardiac dysfunction leads a high risk of long-term cardiovascular morbidity mortality; however, better classification asymptomatic individuals remains challenge.Echocardiographic were identified using K-means clustering the first generation STANISLAS (Yearly non-invasive follow-up Health status Lorraine insured inhabitants) cohort (N = 827;...

10.1016/j.jcmg.2021.07.004 article EN cc-by-nc-nd JACC. Cardiovascular imaging 2021-09-15

Abstract ESC Guidelines provide best practice, evidence-based recommendations for diagnosing and treating patients with cardiovascular diseases. It is not always possible practices to be followed, however, particularly in low-resource settings. To address this issue, a set of guideline-related documents were created identify key priorities users these The highlight the related describe strategies clinicians approach implementation or discuss alternatives which are line intention...

10.1093/ehjqcco/qcae107 article EN other-oa European Heart Journal - Quality of Care and Clinical Outcomes 2025-03-28

Combination lipid-lowering therapy (LLT) after myocardial infarction (MI) achieves lower low-density lipoprotein cholesterol (LDL-C) levels and better cardiovascular outcomes vs statin monotherapy. As a result, global guidelines recommend LDL-C but, paradoxically, advise treatment through stepwise approach. Yet the need for combination is inevitable as <20% of patients achieve goals with statins alone. Whether combining ezetimibe early late MI results in unknown. In this study, authors...

10.1016/j.jacc.2025.02.007 article EN cc-by-nc-nd Journal of the American College of Cardiology 2025-04-01

Abstract Aims Participation in exercise-based cardiac rehabilitation (exCR) increases aerobic capacity and improves outcomes patients following myocardial infarction (MI) is therefore universally recommended. While meta-analyses consistently report that participation exCR reduces cardiovascular mortality, there are conflicting results regarding effects on total mortality. Presently, many eligible do not receive clinical practice. We aimed to investigate the relation between post-MI mortality...

10.1093/eurjpc/zwab083 article EN cc-by-nc European Journal of Preventive Cardiology 2021-05-04

Background A significant proportion of patients with ST-segment-elevation myocardial infarction (MI) have no standard modifiable cardiovascular risk factors (SMuRFs) and unexpected worse 30-day outcomes compared those SMuRFs. The aim this article is to examine non-ST-segment-elevation MI in the absence Methods Results Presenting features, management, without SmuRFs (hypertension, diabetes, hypercholesterolemia, smoking) were Swedish registry SWEDEHEART (Swedish Web-System for Enhancement...

10.1161/jaha.121.024818 article EN cc-by-nc-nd Journal of the American Heart Association 2022-07-25

Non-high-density lipoprotein cholesterol (HDL-C) provides an estimate of lipid-associated risk and is a secondary treatment target after myocardial infarction (MI). The aim was to study the relationship between non-HDL-C levels MI adverse outcomes.

10.1093/eurheartj/ehae576 article EN cc-by European Heart Journal 2024-09-01

While patient performance after participating in cardiac rehabilitation programmes acute myocardial infarction is regularly reported through registry and survey data, information on programme characteristics less well described.The aim of this study was to evaluate Swedish adherence European Guidelines Cardiovascular Disease Prevention.Cardiac at all 78 centres Sweden 2016 were surveyed using a web-based questionnaire (100% response rate). The questions based core components as recommended...

10.1177/2047487319865729 article EN European Journal of Preventive Cardiology 2019-07-26

Despite its well-established positive effects, exercise-based cardiac rehabilitation (exCR) is underused in patients following an acute myocardial infarction (AMI). The aim of the study was to identify factors associated with non-attendance at exCR post-AMI a large Swedish cohort. A total 31,297 who have suffered AMI, mean age 62.4 ± 4 years, were included from SWEDEHEART registry during years 2010-2016. Comparisons between attenders and non-attenders done baseline for variables: age, sex,...

10.1186/s13102-019-0125-9 article EN cc-by BMC Sports Science Medicine and Rehabilitation 2019-07-26

Abstract Aims The quality registry SWEDEHEART covers data across the patient pathway after an acute myocardial infarction (MI), from hospital care to secondary prevention. Although cardiac rehabilitation (CR) is strongly recommended MI, there still heterogeneity regarding standards, uptake, and adherence rates. aim of SWEDEHEART-CR provide continuous information on prevention CR performance support audit development evidence-based practice. To facilitate improvement research initiatives, a...

10.1093/ehjqcco/qcab039 article EN European Heart Journal - Quality of Care and Clinical Outcomes 2021-05-11

The incidence of atherosclerotic cardiovascular disease increases with levels low-density lipoprotein cholesterol (LDL-C). Yet, a paradox may exist where lower LDL-C at myocardial infarction (MI) are associated poorer prognoses.To assess the association between MI risk factor burden and cause-specific outcomes.Statin-naive patients hospitalized for first registered in SWEDEHEART were included. Data linked to Swedish registers. Primary outcomes all-cause mortality nonfatal MI. Associations...

10.1111/joim.13656 article EN cc-by Journal of Internal Medicine 2023-05-31

Objectives The objective of this study was to assess the completeness registration secondary preventive variables comparing on-site visits with telephone consultations during follow-up after myocardial infarction. Design This an observational based on Swedish quality registry SWEDEHEART. Setting and outcome measures We analysed proportion missing values for major target data registered at 2-month 1-year visits, 2006–2022 (n=101 199). χ 2 tests were used compare differences in consultations....

10.1136/bmjopen-2024-087881 article EN cc-by-nc-nd BMJ Open 2025-01-01

Participation in exercise-based cardiac rehabilitation (EBCR) improves long-term prognosis for patients following myocardial infarction (MI). Evaluating the effects of EBCR is challenging due to voluntary nature participation program. Using register data on 18,978 hospitalized MI 2011 2013 Sweden, a non-experimental study design employed evaluate health-related quality life (HRQoL). Conditional independence from non-random treatment assignment considered through set potential-outcome (PO)...

10.1101/2025.01.12.25320433 preprint EN cc-by medRxiv (Cold Spring Harbor Laboratory) 2025-01-14

Abstract Background Closing the evidence-practice gap for treatment of acute coronary syndrome (ACS) is central to improving quality care. Under European Society Cardiology (ESC) framework, we aimed develop updated indicators (QIs) evaluation care and outcomes patients with ACS. Methods A Working Group experts including members ESC Clinical Practice Guidelines Task Force ACS, Acute CardioVascular Care Association Percutaneous Cardiovascular Interventions followed methodology QI development....

10.1093/ehjacc/zuaf014 article EN other-oa European Heart Journal Acute Cardiovascular Care 2025-01-28

Abstract Background Cardiac telerehabilitation addresses common barriers for attendance at exercise-based cardiac rehabilitation (EBCR). Pragmatic real-world studies are however lacking, limiting generalisability of available evidence. We aimed to evaluate feasibility, safety, and patient perceptions remotely delivered EBCR in a multicentre clinical practice setting after myocardial infarction (MI). Methods This study included 232 post-MI patients (63.7 years, 77.5% men) from 23 centres...

10.1093/ehjdh/ztaf014 article EN cc-by-nc European Heart Journal - Digital Health 2025-03-04

Stroke and acute myocardial infarction (AMI) rank among the leading causes of mortality. Physical activity exercise are recommended as part rehabilitation after AMI to prevent cardiovascular events, but importance for stroke prevention has not been investigated using population-based data. To determine associations between participation in exercise-based cardiac (EBCR) self-reported physical with risk total stroke, ischemic intracerebral hemorrhage AMI. This was a nationwide, double cohort...

10.1016/j.rehab.2025.101971 article EN cc-by Annals of Physical and Rehabilitation Medicine 2025-04-19
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