Borja Ibáñez

ORCID: 0000-0002-5036-254X
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Research Areas
  • Cardiac Imaging and Diagnostics
  • Acute Myocardial Infarction Research
  • Cardiac Ischemia and Reperfusion
  • Cardiovascular Function and Risk Factors
  • Cardiac electrophysiology and arrhythmias
  • Coronary Interventions and Diagnostics
  • Cardiac Arrest and Resuscitation
  • Advanced MRI Techniques and Applications
  • Heart Failure Treatment and Management
  • Cardiovascular Disease and Adiposity
  • Lipoproteins and Cardiovascular Health
  • Pulmonary Hypertension Research and Treatments
  • Cardiovascular Health and Disease Prevention
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Cardiac, Anesthesia and Surgical Outcomes
  • Cerebrovascular and Carotid Artery Diseases
  • Atrial Fibrillation Management and Outcomes
  • Cardiac Health and Mental Health
  • Cardiac Structural Anomalies and Repair
  • Cardiac Valve Diseases and Treatments
  • Takotsubo Cardiomyopathy and Associated Phenomena
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiac Fibrosis and Remodeling
  • Cardiac Arrhythmias and Treatments

Spanish National Centre for Cardiovascular Research
2016-2025

Centro de Investigación en Red en Enfermedades Cardiovasculares
2017-2025

Hospital Universitario Fundación Jiménez Díaz
2016-2025

Centro de Investigación Biomédica en Red
2017-2025

Instituto de Salud Carlos III
2012-2025

University of Concepción
2024

Universidad Autónoma de Madrid
2004-2024

Complejo Hospitalario de Salamanca
2017-2024

Hospital Universitario Quirónsalud Madrid
2014-2024

Centre for Biomedical Network Research on Rare Diseases
2020-2023

Borja Ibáñez Stefan James Stefan Agewall Manuel J. Antunes Chiara Bucciarelli‐Ducci and 95 more Héctor Bueno Alida L.P. Caforio Filippo Crea John Goudevenos Sigrun Halvorsen Gerhard Hindricks Adnan Kastrati Mattie Lenzen Eva Prescott Marco Roffi Marco Valgimigli Christoph Varenhorst Pascal Vranckx Petr Widimský Jean‐Philippe Collet Steen Dalby Kristensen Victor Aboyans Andreas Baumbach Raffaele Bugiardini Ioan Mircea Coman Victoria Delgado Donna Fitzsimons Oliver Gaemperli Anthony Gershlick Stephan Gielen Veli‐Pekka Harjola Hugo A. Katus Juhani Knuuti Philippe Kolh Christophe Leclercq Gregory Y.H. Lip João Morais Aleksandar Nešković Franz‐Josef Neumann Alexander Niessner Massimo Piepoli Dimitrios Richter Е. V. Shlyakhto Iain A. Simpson Philippe Gabríel Steg Christian Juhl Terkelsen Kristian Thygesen Stephan Windecker José Luis Zamorano Uwe Zeymer Stephan Windecker Victor Aboyans Stefan Agewall Emanuele Barbato Héctor Bueno António Coca Jean‐Philippe Collet Ioan Mircea Coman Verónica Dean Victoria Delgado Donna Fitzsimons Oliver Gaemperli Gerhard Hindricks Bernard Iung Peter Jüni Hugo A. Katus Juhani Knuuti Patrizio Lancellotti Christophe Leclercq Theresa A. McDonagh Massimo Piepoli Piotr Ponikowski Dimitrios Richter Marco Roffi Е. V. Shlyakhto Iain A. Simpson José Luis Zamorano Mohamed Chettibi Hamlet Hayrapetyan Bernhard Metzler Firdovsi İbrahimov Volha Sujayeva Christophe Beauloye Larisa Dizdarević‐Hudić Kiril Karamfiloff Boško Škorić Loizos Antoniades Petr Toušek PetrChristian Juhl Terkelsen Sameh Shaheen Toomas Marandi Matti Niemelä Saško Kedev Martine Gilard Alexander Aladashvili Albrecht Elsaesser Ioannis Georgios Kanakakis Béla Merkely Þórarinn Guðnason Zaza Iakobishvili

2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation The Task Force European Society Cardiology (ESC)

10.1093/eurheartj/ehx393 article EN European Heart Journal 2017-08-26
Franz‐Josef Neumann Miguel Sousa‐Uva Anders Ahlsson Fernándo Alfonso Adrian Banning and 95 more Umberto Benedetto Robert A. Byrne Jean‐Philippe Collet Volkmar Falk Stuart J. Head Peter Jüni Adnan Kastrati Ákos Koller Steen Dalby Kristensen Josef Niebauer Dimitrios Richter Petar M Seferović Dirk Sibbing Giulio Stefanini Stephan Windecker Rashmi Yadav M. Zembala William Wijns David Glineur Victor Aboyans Stephan Achenbach Stefan Agewall Felicita Andreotti Emanuele Barbato Andreas Baumbach James M. Brophy Héctor Bueno Patrick A. Calvert Davide Capodanno Piroze Davierwala Victoria Delgado Dariusz Dudek Nick Freemantle Christian Funck‐Brentano Oliver Gaemperli Stephan Gielen Martine Gilard Bülent Görenek Joerg Haasenritter Michael Haude Borja Ibáñez Bernard Iung Anders Jeppsson Demosthenes G. Katritsis Juhani Knuuti Philippe Kolh Adelino Leite‐Moreira Lars H. Lund Francesco Maisano Julinda Mehilli Bernhard Metzler Gilles Montalescot Duilio Pagano Anna Sonia Petronio Massimo Piepoli Bogdan A. Popescu Rafael Sádaba Е. V. Shlyakhto Sigmund Silber Iain A. Simpson David Sparv Giuseppe Tavilla Hölger Thiele Petr Toušek Éric Van Belle Pascal Vranckx Adam Witkowski José Luis Zamorano Marco Roffi Stephan Windecker Victor Aboyans Stefan Agewall Emanuele Barbato Héctor Bueno António Coca Jean‐Philippe Collet Ioan Mircea Coman Verónica Dean Victoria Delgado Donna Fitzsimons Oliver Gaemperli Gerhard Hindricks Bernard Iung Peter Jüni Hugo A. Katus Juhani Knuuti Patrizio Lancellotti Christophe Leclercq Theresa A. McDonagh Massimo Piepoli Piotr Ponikowski Dimitrios Richter Marco Roffi Е. V. Shlyakhto Miguel Sousa‐Uva

10.1093/eurheartj/ehy394 article ES European Heart Journal 2018-08-25
Kristian Thygesen Joseph S. Alpert Allan S. Jaffe Bernard R. Chaitman Jeroen J. Bax and 95 more David A. Morrow Harvey D. White Kristian Thygesen Joseph S. Alpert Allan S. Jaffe Bernard R. Chaitman Jeroen J. Bax David A. Morrow Harvey D. White Hans Mickley Filippo Crea Frans Van de Werf Chiara Bucciarelli‐Ducci Hugo A. Katus Fausto J. Pinto Elliott M. Antman Christian W. Hamm Raffaele De Caterina James L. Januzzi Fred S. Apple María Ángeles Alonso García S. Richard Underwood John M. Canty Alexander R. Lyon P.J. Devereaux José Luis Zamorano Bertil Lindahl William S. Weintraub L. Kristin Newby Renu Virmani Pascal Vranckx Don Cutlip Raymond J. Gibbons Sidney C. Smith Dan Atar Russell V. Luepker Rose Marie Robertson Robert O. Bonow Philippe Gabríel Steg Patrick T. O’Gara Keith A.A. Fox David Hasdai Victor Aboyans Stephan Achenbach Stefan Agewall Thomas Alexander Álvaro Avezum Emanuele Barbato Jean‐Pierre Bassand Eric Bates John A. Bittl Güenter Breithardt Héctor Bueno Raffaele Bugiardini Mauricio G. Cohen George Dangas James A. de Lemos Victoria Delgado Gerasimos Filippatos Edward T.A. Fry Christopher B. Granger Sigrun Halvorsen Mark A. Hlatky Borja Ibáñez Stefan James Adnan Kastrati Christophe Leclercq Kenneth W. Mahaffey Laxmi S. Mehta Christian Müller Carlo Patrono Massimo Piepoli Daniel Piñeiro Marco Roffi Andrea Rubboli Samin K. Sharma Iain A. Simpson Michał Tendera Marco Valgimigli Allard C. van der Wal Stephan Windecker Mohamed Chettibi Hamlet Hayrapetyan Franz Xaver Roithinger Farid Aliyev Volha Sujayeva Marc J. Claeys Elnur Smajić Petr Kala Kasper Karmak Iversen Ehab E. El Hefny Toomas Marandi Pekka Porela Slobodan Antov Martine Gilard

Kristian Thygesen∗ (Denmark) Joseph S. Alpert∗ (USA) Allan Jaffe (USA) Bernard R. Chaitman (USA) Jeroen J. Bax (The Netherlands) David A. Morrow (USA) Harvey D. White∗ (New Zealand) Hans Mickley (Denmark) Filippo Crea (Italy) Frans Van de Werf (Belgium) Chiara Bucciarelli-Ducci (

10.1093/eurheartj/ehy462 article EN European Heart Journal 2018-08-25
Marco Valgimigli Héctor Bueno Robert A. Byrne Jean‐Philippe Collet Francesco Costa and 95 more Anders Jeppsson Peter Jüni Adnan Kastrati Philippe Kolh Laura Mauri Gilles Montalescot Franz‐Josef Neumann Mate Petričević Marco Roffi Philippe Gabríel Steg Stephan Windecker José Luis Zamorano Glenn N. Levine Lina Badimón Pascal Vranckx Stefan Agewall Felicita Andreotti Elliott M. Antman Emanuele Barbato Jean‐Pierre Bassand Raffaele Bugiardini Mustafa Çıkırıkçıoğlu Thomas Cuisset Michele De Bonis Victoria Delgado Donna Fitzsimons Oliver Gaemperli Nazzareno Galiè Martine Gilard Christian W. Hamm Borja Ibáñez Bernard Iung Stefan James Juhani Knuuti Ulf Landmesser Christophe Leclercq Maddalena Lettino Gregory Y.H. Lip Massimo Piepoli Luc Piérard Markus Schwerzmann Udo Sechtem Iain A. Simpson Miguel Sousa‐Uva Eugenio Stabile Robert F. Storey Michał Tendera Frans Van de Werf Freek W.A. Verheugt Victor Aboyans Stephan Windecker Victor Aboyans Stefan Agewall Emanuele Barbato Héctor Bueno António Coca Jean‐Philippe Collet Ioan Mircea Coman Verónica Dean Victoria Delgado Donna Fitzsimons Oliver Gaemperli Gerhard Hindricks Bernard Iung Peter Jüni Hugo A. Katus Juhani Knuuti Patrizio Lancellotti Christophe Leclercq Theresa A. McDonagh Massimo Piepoli Piotr Ponikowski Dimitrios Richter Marco Roffi Е. V. Shlyakhto Iain A. Simpson José Luis Zamorano Stephan Windecker Victor Aboyans Stefan Agewall Emanuele Barbato Héctor Bueno António Coca Jean‐Philippe Collet Ioan Mircea Coman Verónica Dean Victoria Delgado Donna Fitzsimons Oliver Gaemperli Gerhard Hindricks Bernard Iung Peter Jüni Hugo A. Katus Juhani Knuuti Patrizio Lancellotti

The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge evidence available at time their publication.The is not responsible in event any contradiction, discrepancy and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...

10.1093/eurheartj/ehx419 article EN European Heart Journal 2017-08-26
Robert A. Byrne Xavier Rosselló J J Coughlan Emanuele Barbato Colin Berry and 95 more Alaide Chieffo Marc J. Claeys Gheorghe‐Andrei Dan Marc R. Dweck Mary Galbraith Martine Gilard Lynne Hinterbuchner Ewa A. Jankowska Peter Jüni Takeshi Kimura Vijay Kunadian Margrét Leósdóttir Roberto Lorusso Roberto F.E. Pedretti Angelos G. Rigopoulos María Rubini Giménez Hölger Thiele Pascal Vranckx Sven Waßmann Nanette K. Wenger Borja Ibáñez Sigrun Halvorsen Stefan James Magdy Abdelhamid Victor Aboyans Nina Ajmone Marsan Sotiris Antoniou Riccardo Asteggiano Maria Bäck Davide Capodanno Rubén Casado-Arroyo Salvatore Cassese Jelena Čelutkienė Maja Čikeš Jean‐Philippe Collet Grégory Ducrocq Volkmar Falk Laurent Fauchier Tobias Geisler Diana A. Gorog Lene Holmvang Tiny Jaarsma Hywel Wynne Jones Lars Køber Konstantinos C. Koskinas Dipak Kotecha Konstantin A. Krychtiuk Ulf Landmesser George Lazaros Basil S. Lewis Bertil Lindahl Aleš Linhart Maja‐Lisa Løchen Mamas A. Mamas John W. McEvoy Borislava Mihaylova Richard Mindham Christian Mueller Lis Neubeck Josef Niebauer Jens Cosedis Nielsen Alexander Niessner Valeria Paradies Agnès Pasquet Steffen E. Petersen Eva Prescott Amina Rakisheva Bianca Rocca Giuseppe Rosano Leyla Elif Sade François Schiele Jolanta M. Siller‐Matula Christian Sticherling Robert F. Storey Matthias Thielmann Christiaan Vrints Stephan Windecker Rune Wiseth Adam Witkowski Mohammed El Amine Bouzid Hamlet Hayrapetyan Bernhard Metzler Patrizio Lancellotti Mugdim Bajrić Kiril Karamfiloff Andreas Mitsis Petr Ošťádal Rikke Sørensen Tamer Elwasify Toomas Marandi Essi Ryödi Jean‐Philippe Collet Archil Chukhrukidze Julinda Mehilli Periklis Davlouros

10.1093/eurheartj/ehad191 article EN European Heart Journal 2023-08-25
Theresa A. McDonagh Marco Metra Marianna Adamo Roy S. Gardner Andreas Baumbach and 95 more Michael Böhm Haran Burri Javed Butler Jelena Čelutkienė Ovidiu Chioncel John G.F. Cleland María G. Crespo‐Leiro Dimitrios Farmakis Martine Gilard Stéphane Heymans Arno W. Hoes Tiny Jaarsma Ewa A. Jankowska Mitja Lainščak Carolyn S.P. Lam Alexander R. Lyon John J.V. McMurray Alexandre Mebazaa Richard Mindham Claudio Muneretto Massimo Piepoli Susanna Price Giuseppe Rosano Frank Ruschitzka Anne Kathrine Skibelund Rudolf A. de Boer P. Christian Schulze Elena Arbelo Jozef Bartúnek Johann Bauersachs Michael A. Borger Sergio Buccheri Elisabetta Cerbai Erwan Donal Frank Edelmann Gloria Färber Bettina Heidecker Borja Ibáñez Stefan James Lars Køber Konstantinos C. Koskinas Josep Masip John W. McEvoy Robert J. Mentz Borislava Mihaylova Jacob Eifer Møller Wilfried Müllens Lis Neubeck Jens Cosedis Nielsen Agnès Pasquet Piotr Ponikowski Eva Prescott Amina Rakisheva Bianca Rocca Xavier Rosselló Leyla Elif Sade Hannah Schaubroeck Elena Tessitore Mariya Tokmakova Peter van der Meer Isabelle C. Van Gelder Mattias Van Heetvelde Christiaan Vrints Matthias Wilhelm Adam Witkowski Katja Zeppenfeld Naltin Shuka Mohammed Chettibi Hamlet Hayrapetyan Noémi Pávó Aysel İslamlı Anne‐Catherine Pouleur Zumreta Kušljugić Mariya Tokmakova Davor Miličić Theodoros Christodoulides Filip Málek Lars Køber M. Koriem Pentti Põder Johan Lassus François Roubille Vaja Agladze Stefan Frantz Alexia Stavrati Annamária Kosztin Inga Jóna Ingimarsdóttir Patricia Campbell Tal Hasin Fabrizio Oliva Nazipa Aidargaliyeva Gani Bajraktari Erkin М Мirrakhimov Ginta Kamzola Ali M El Neihoum

Poland), and Katja Zeppenfeld (

10.1093/eurheartj/ehad195 article EN European Heart Journal 2023-08-25
Victoria Delgado Nina Ajmone Marsan Suzanne de Waha Nikolaos Bonaros Margarita Brida and 95 more Haran Burri Stefano Caselli Torsten Doenst Stéphane Éderhy Paola Anna Erba Dan Foldager Emil Loldrup Fosbøl Jan Kovac Carlos A. Mestres Owen Miller José M. Miró Michal Pazderník M.N. Pizzi Eduard Quintana Trine Bernholdt Rasmussen Arsen Ristić Josep Rodés‐Cabau Alessandro Sionís Liesl Zühlke Michael A. Borger Bernard Iung Bernard Prendergast Magdy Abdelhamid Marianna Adamo Riccardo Asteggiano Larry M. Baddour Jelena Čelutkienė John B. Chambers Jean‐Claude Deharo Wolfram Doehner Laura Dos Xavier Duval Volkmar Falk Laurent Fauchier Núria Fernández-Hidalgo Christian G. Giske Anežka Gombošová Gilbert Habib Borja Ibáñez Tiny Jaarsma Lars Køber Konstantinos C. Koskinas Dipak Kotecha Ulf Landmesser Sandra Lauck Basil S. Lewis Maja‐Lisa Løchen John W. McEvoy Borislava Mihaylova Richard Mindham Lis Neubeck Jens Cosedis Nielsen Jean‐François Obadia Agnès Pasquet Steffen E. Petersen Eva Prescott Susanna Price Amina Rakisheva Archana Rao François Rouzet Jonathan Sandoe Renate B. Schnabel Christine Selton‐Suty Lars Søndergaard Martin H. Thornhill Konstantinos Toutouzas Nico Van de Veire Isidre Vilacosta Christiaan Vrints Olaf Wendler Yasmina Benchabi A. L. Chilingaryan Sebastian J. Reinstadler Fuad Samadov Bernard P. Paelinck Zumreta Kušljugić Elena Kinova Maja Čikeš I. Michaloliakos Martin Mates Jonas Agerlund Povlsen Mohammad Abdelghani Liisi Küünal-Arge Helena Rajala Christine Selton‐Suty Zurab Pagava Marcus Franz Alexandros Patrianakos Judit Barta Þórdís Jóna Hrafnkelsdóttir David Moore Katia Orvin Fabrizio Oliva Gyulnar Zhussupova Gani Bajraktari

10.1093/eurheartj/ehad193 article EN European Heart Journal 2023-08-25
Nikolaus Marx Massimo Federici Katharina Schütt Dirk Müller‐Wieland Ramzi Ajjan and 95 more Manuel J. Antunes Ruxandra Christodorescu Carolyn Crawford Emanuele Di Angelantonio Björn Eliasson Christine Espinola‐Klein Laurent Fauchier Martin Halle William G. Herrington Alexandra Kautzky‐Willer Ekaterini Lambrinou Maciej Lesiak Maddalena Lettino Darren K. McGuire Wilfried Müllens Bianca Rocca Naveed Sattar Eva Prescott Francesco Cosentino Magdy Abdelhamid Victor Aboyans Sotiris Antoniou Riccardo Asteggiano Iris Baumgärtner Sergio Buccheri Héctor Bueno Jelena Čelutkienė Alaide Chieffo Christina Christersson Andrew J.S. Coats Bernard Cosyns Martin Czerny Christi Deaton Volkmar Falk Brian A. Ference Gerasimos Filippatos Miles Fisher Heikki Huikuri Borja Ibáñez Tiny Jaarsma Stefan James Kamlesh Khunti Lars Køber Konstantinos C. Koskinas Basil S. Lewis Maja‐Lisa Løchen John W. McEvoy Borislava Mihaylova Richard Mindham Lis Neubeck Jens Cosedis Nielsen Gianfranco Parati Agnès Pasquet Carlo Patrono Steffen E. Petersen Massimo Piepoli Amina Rakisheva Xavier Rosselló Peter Rossing Lars Rydén Eberhard Standl Lâle Tokgözoğlu Rhian M. Touyz Frank L.J. Visseren Massimo Volpe Christiaan Vrints Adam Witkowski Lusine Hazarapetyan Andreas Zirlik Yasmin Rustamova Philippe van de Borne Dragan Lović Nina Gotcheva Davor Miličić Petros Agathangelou Michal Vrablı́k Morten Schou Hosam Hasan‐Ali Margus Viigimaa Riikka Lautamäki Victor Aboyans Zurab Klimiashvili Malte Kelm Gerasimos Siasos Róbert Gábor Kiss Berglind Libungan Maeve Durkan Barak Zafrir Furio Colivicchi Meiramgul Tundybayeva Ibadete Bytyçi Erkin М Мirrakhimov Kārlis Trušinskis Georges Saadé Jolita Badarienė

The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge evidence available at time their publication.The is not responsible in event any contradiction, discrepancy, and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...

10.1093/eurheartj/ehad192 article EN cc-by-nc-nd European Heart Journal 2023-08-25
Sigrun Halvorsen Julinda Mehilli Salvatore Cassese Trygve S. Hall Magdy Abdelhamid and 95 more Emanuele Barbato Stefan De Hert Ingrid de Laval Tobias Geisler Lynne Hinterbuchner Borja Ibáñez Radosław Lenarczyk Ulrich Mansmann Paul McGreavy Christian Mueller Claudio Muneretto Alexander Niessner Tatjana Potpara Arsen Ristić Leyla Elif Sade Henrik Schirmer Stefanie Schüpke Henrik Sillesen Helge Skulstad Lucia Torracca Oktay Tutarel Peter van der Meer Wojciech Wojakowski Kai Zacharowski Juhani Knuuti Steen Dalby Kristensen Victor Aboyans Ingo Ahrens Sotiris Antoniou Riccardo Asteggiano Dan Atar Andreas Baumbach Helmut Baumgartner Michael Böhm Michael A. Borger Héctor Bueno Jelena Čelutkienė Alaide Chieffo Maya Cikes Harald Darius Victoria Delgado P.J. Devereaux David Duncker Volkmar Falk Laurent Fauchier Gilbert Habib David Hasdai Kurt Huber Bernard Iung Tiny Jaarsma А. О. Конради Konstantinos C. Koskinas Dipak Kotecha Ulf Landmesser Basil S. Lewis Aleš Linhart Maja Lisa Løchen Michael Mæng Stéphane Manzo‐Silberman Richard Mindham Lis Neubeck Jens Cosedis Nielsen Steffen E. Petersen Eva Prescott Amina Rakisheva Antti Saraste Dirk Sibbing Jolanta M. Siller‐Matula Marta Sitges Ivan Stanković Robert F. Storey Jurriën M. ten Berg Matthias Thielmann Rhian M. Touyz Mohammed Amine Bouzid Hamayak Sisakian Bernhard Metzler Vadim Shumavets Agnès Pasquet Elnur Smajić Maria Milanova Boško Škorić Maria Karakyriou Hana Skalická Michael Mæng Bassem Abd Elhamid Arno Ruusalepp Kati Valtola Ariel Cohen Archil Chukhrukidze Ilka Ott Nikos Kafkas Zoltán Járai Þórdís Jóna Hrafnkelsdóttir Patricia Campbell

All experts involved in

10.1093/eurheartj/ehac270 article EN European Heart Journal 2022-08-26

Mitochondrial morphology is shaped by fusion and division of their membranes. Here, we found that adult myocardial function depends on balanced mitochondrial fission, maintained processing the dynamin-like guanosine triphosphatase OPA1 peptidases YME1L OMA1. Cardiac-specific ablation Yme1l in mice activated OMA1 accelerated proteolysis, which triggered fragmentation altered cardiac metabolism. This caused dilated cardiomyopathy heart failure. Cardiac were rescued Oma1 deletion, prevented...

10.1126/science.aad0116 article EN Science 2015-12-03

Background— Data are limited on the presence, distribution, and extent of subclinical atherosclerosis in middle-aged populations. Methods Results— The PESA (Progression Early Subclinical Atherosclerosis) study prospectively enrolled 4184 asymptomatic participants 40 to 54 years age (mean age, 45.8 years; 63% male) evaluate systemic carotid, abdominal aortic, iliofemoral territories by 2-/3-dimensional ultrasound coronary artery calcification computed tomography. atherosclerosis, defined as...

10.1161/circulationaha.114.014310 article EN Circulation 2015-04-17

The effect of immunometabolism on age-associated diseases remains uncertain. In this work, we show that T cells with dysfunctional mitochondria owing to mitochondrial transcription factor A (TFAM) deficiency act as accelerators senescence. mice, these instigate multiple aging-related features, including metabolic, cognitive, physical, and cardiovascular alterations, which together result in premature death. cell metabolic failure induces the accumulation circulating cytokines, resembles...

10.1126/science.aax0860 article EN Science 2020-05-21

The ESC Guidelines represent the views of and were produced after careful consideration scientific medical knowledge evidence available at time their publication.The is not responsible in event any contradiction, discrepancy and/or ambiguity between other official recommendations or guidelines issued by relevant public health authorities, particular relation to good use healthcare therapeutic strategies.Health professionals are encouraged take fully into account when exercising clinical...

10.1093/ejcts/ezx334 article EN European Journal of Cardio-Thoracic Surgery 2017-08-26
Christiaan Vrints Felicita Andreotti Konstantinos C. Koskinas Xavier Rosselló Marianna Adamo and 95 more James Ainslie Adrian Banning Andrzej Budaj Ronny R. Buechel Giovanni Alfonso Chiariello Alaide Chieffo Ruxandra Christodorescu Christi Deaton Torsten Doenst Hywel Wynne Jones Vijay Kunadian Julinda Mehilli Milan Milojevic Jan J. Piek Francesca Pugliese Andrea Rubboli Anne Grete Semb Roxy Senior Jurriën M. ten Berg Éric Van Belle Emeline M. Van Craenenbroeck Rafael Vidal-Pérez Simon Winther Michael A. Borger Ingibjörg Guđmundsdóttir Juhani Knuuti Ingo Ahrens Michael Böhm Sergio Buccheri Davide Capodanno Evald Høj Christiansen Jean‐Philippe Collet Kenneth Dickstein Christian Eek Volkmar Falk Peter Henriksen Borja Ibáñez Stefan James Saško Kedev Lars Køber Martha Kyriakou Emma Magavern Angela McInerney John W. McEvoy Caius Ovidiu Mersha Borislava Mihaylova Richard Mindham Lis Neubeck Franz–Josef Neumann Jens Cosedis Nielsen Pasquale Paolisso Valeria Paradies Agnès Pasquet Massimo Piepoli Eva Prescott Amina Rakisheva Bianca Rocca Marc Ruel Sigrid Sandner Antti Saraste Karolina Szummer Ilonca Vaartjes William Wijns Stephan Windecker Adam Witkowsky Marija Zdrakovic Katja Zeppenfeld Naltin Shuka Mohamed Abed Bouraghda Hamlet Hayrapetyan Sebastian J. Reinstadler Ogtay Musayev Michel De Pauw Zumreta Kušljugić Валери Гелев Boško Škorić Maria Karakyriou Tomáš Kovárník L H Nielsen Inas Mohamed Abdelaziz Tiia Ainla Pekka Porela Hakim Benamer Kakha Nadaraia Gert Richardt Michail I. Papafaklis Dávid Becker Ingibjörg Guđmundsdóttir Arik Wolak Carmine Riccio Bekbolat Zholdin Shpend Elezi S. Abilova Iveta Mintale Bachir Allam

10.1093/eurheartj/ehae177 article EN other-oa European Heart Journal 2024-08-30

The effect of β-blockers on infarct size when used in conjunction with primary percutaneous coronary intervention is unknown. We hypothesize that metoprolol reduces administered early (intravenously before reperfusion).Patients Killip class II or less anterior ST-segment-elevation myocardial infarction (STEMI) undergoing within 6 hours symptoms onset were randomized to receive intravenous (n=131) not (control, n=139) reperfusion. All patients without contraindications received oral 24 hours....

10.1161/circulationaha.113.003653 article EN Circulation 2013-09-04
Isabelle C. Van Gelder Michiel Rienstra Karina V Bunting Rubén Casado-Arroyo Valeria Caso and 95 more Harry J.G.M. Crijns Tom De Potter Jeremy Dwight Luigina Guasti Thorsten Hanke Tiny Jaarsma Maddalena Lettino Maja‐Lisa Løchen R. Thomas Lumbers Bart Maesen Inge Mølgaard Giuseppe Rosano Prashanthan Sanders Renate B. Schnabel Piotr Suwalski Emma Svennberg Juan Tamargo Otilia Țica Vassil Traykov Stylianos Tzeis Dipak Kotecha Nikolaos Dagres Bianca Rocca Syed Ahsan Pietro Ameri Elena Arbelo Axel Bauer Michael A. Borger Sergio Buccheri Barbara Casadei Ovidiu Chioncel Dobromir Dobrev Laurent Fauchier Bruna Gigante Michael Glikson Ziad Hijazi Gerhard Hindricks Daniela Husser Borja Ibáñez Stefan James Stefan Kääb Paulus Kirchhof Lars Køber Konstantinos C. Koskinas Thomas Kümler Gregory Y H Lip John Mandrola Nikolaus Marx John William Mcevoy Borislava Mihaylova Richard Mindham Denisa Muraru Lis Neubeck Jens Cosedis Nielsen Jonas Oldgren Maurizio Paciaroni Agnès Pasquet Eva Prescott Filip Rega Francisco Javier Rossello Marcin Ruciński Sacha P. Salzberg Sam Schulman Philipp Sommer Jesper Hastrup Svendsen Jurriën M. ten Berg Hugo Ten Cate Ilonca Vaartjes Christiaan Vrints Adam Witkowski Katja Zeppenfeld Leonard Simoni B. Kichou Hamayak Sisakian Douglas S. Scherr Frank Cools Elnur Smajić Tchavdar Shalganov Šime Manola Panayiotis Avraamides Miloš Táborský Axel Brandes Ahmed M El-Damaty Priit Kampus Pekka Raatikainen Rodrigue Garcia Kakhaber Etsadashvili Lars Eckardt Eleftherios M. Kallergis László Gellér Kristján Guðmundsson Jonathan Lyne Ibrahim Marai Furio Colivicchi Ayan Abdrakhmanov

ESC.

10.1093/eurheartj/ehae176 article EN other-oa European Heart Journal 2024-08-30
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