- Heart Failure Treatment and Management
- Mechanical Circulatory Support Devices
- Cardiac Arrest and Resuscitation
- Cardiovascular Function and Risk Factors
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Cardiac pacing and defibrillation studies
- Dialysis and Renal Disease Management
- Acute Kidney Injury Research
- Hemodynamic Monitoring and Therapy
- Cardiac electrophysiology and arrhythmias
- Potassium and Related Disorders
- Sepsis Diagnosis and Treatment
- Cardiac Fibrosis and Remodeling
- Diabetes Treatment and Management
- Chronic Kidney Disease and Diabetes
- Electrolyte and hormonal disorders
- Blood Pressure and Hypertension Studies
- Ultrasound in Clinical Applications
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Cardiac Imaging and Diagnostics
- Renal function and acid-base balance
- Cardiac Ischemia and Reperfusion
- GDF15 and Related Biomarkers
- Cardiovascular Health and Disease Prevention
Helsinki University Hospital
2016-2025
University of Helsinki
2012-2025
Hôpital Louis Pradel
2019
Hospices Civils de Lyon
2019
Lung Institute
2017-2018
Turku University Hospital
2017
Satakunta Central Hospital
2017
Inserm
2012-2016
Universitat Autònoma de Barcelona
2016
Hospital de Sant Pau
2016
The objective of the EuroHeart Failure Survey II (EHFS II) was to assess patient characteristics, aetiology, treatment, and outcome acute heart failure (AHF) in Europe relation guidelines on diagnosis treatment AHF published by European Society Cardiology.Patients hospitalized for were recruited 133 centres 30 countries. Three thousand five hundred eighty patients entered into database end August 2005. Mean age 70 years, 61% male. New-onset (de novo AHF) diagnosed 37%, which 42% due coronary...
Poland), and Katja Zeppenfeld (
Whether acetazolamide, a carbonic anhydrase inhibitor that reduces proximal tubular sodium reabsorption, can improve the efficiency of loop diuretics, potentially leading to more and faster decongestion in patients with acute decompensated heart failure volume overload, is unclear.
Vasopressors and inotropes remain a cornerstone in stabilization of the severely impaired hemodynamics cardiac output cardiogenic shock (CS). The aim this study was to analyze current real-life use these medications, their impact on outcome changes renal biomarkers over time CS.The multinational CardShock prospectively enrolled 219 patients with CS. vasopressors analyzed relation primary outcome, i.e., 90-day mortality, propensity score methods 216 follow-up data available. Changes until 96...
Acute heart failure (AHF) is associated with poor prognosis and requires recurrent hospitalizations. However, studies on AHF characteristics, treatment, prognostic factors are few. Our aim was to investigate the 1-year of identify in different clinical groups.We conducted a prospective multicentre study 620 patients hospitalized due AHF; mean age 75.1 (10.4) years, 50% male. Half had new-onset failure. congestion (63.5%) pulmonary oedema (26.3%) were most common presentations. Left...
Cystatin C, a novel marker of renal function, has been implicated as prognostic in cardiovascular disease. We investigated the value cystatin C acute heart failure (AHF) comparison to other markers function and NT-proBNP. Patients with measurements (n = 480) from prospective multicentre study on AHF were included. All-cause mortality at 12 months was 25.4%. creatinine, age, gender, systolic blood pressure admission identified independent risk factors. above median (1.30 mg/L) associated...
Increases in plasma B-type natriuretic peptide (BNP) concentrations those with acutely decompensated heart failure (ADHF) has been mainly attributed to an increase NPPB gene transcription. Recently, proBNP glycosylation emerged as a potential regulatory mechanism the production of amino-terminal (NT)-proBNP and BNP. The aim present study was investigate glycosylation, corin furin activities ADHF patients.Plasma levels proBNP, NT-proBNP, BNP, well concentration activity were measured large...