A5071287538- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Atherosclerosis and Cardiovascular Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic aneurysm repair treatments
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Lipoproteins and Cardiovascular Health
- Cardiovascular Effects of Exercise
- Angiogenesis and VEGF in Cancer
- Cardiovascular Disease and Adiposity
- Cardiovascular Health and Disease Prevention
- Acute Ischemic Stroke Management
- Cardiac tumors and thrombi
- Cell Adhesion Molecules Research
- Vascular Procedures and Complications
- Cardiac Arrhythmias and Treatments
- Atrial Fibrillation Management and Outcomes
- Aortic Thrombus and Embolism
- Protease and Inhibitor Mechanisms
- Venous Thromboembolism Diagnosis and Management
CVPath Institute
2016-2025
Johns Hopkins University
1989-2024
University of Maryland, Baltimore
2002-2024
Icahn School of Medicine at Mount Sinai
2011-2023
University of British Columbia
2004-2022
Houston Methodist
2017-2022
Yale University
2022
Abbott Vascular (United States)
2009-2021
Terumo (Germany)
2009-2021
OrbusNeich (China)
2010-2021
Kristian Thygesen∗ (Denmark) Joseph S. Alpert∗ (USA) Allan Jaffe (USA) Bernard R. Chaitman (USA) Jeroen J. Bax (The Netherlands) David A. Morrow (USA) Harvey D. White∗ (New Zealand) Hans Mickley (Denmark) Filippo Crea (Italy) Frans Van de Werf (Belgium) Chiara Bucciarelli-Ducci (
The purpose of this document is to make the output International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and Validation available medical scientific communities, through a peer-reviewed publication, in interest improving diagnosis treatment patients with atherosclerosis, including coronary artery disease. optical coherence tomography (IVOCT) catheter-based modality that acquires images at resolution ∼10 μm, enabling visualization blood vessel...
Background— The US Food and Drug Administration recently issued a warning of subacute thrombosis hypersensitivity reactions to sirolimus-eluting stents (Cypher). cause incidence these events have not been determined. Methods Results— We present findings 58-year-old man who died late stent 18 months after receiving 2 Cypher for unstable angina. Although angiographic intravascular ultrasound results at 8 demonstrated the absence neointimal formation, vessel enlargement was present. An autopsy...
Heart failure can result from a variety of causes, including ischemic, hypertensive, toxic, and inflammatory heart disease. However, the cellular mechanisms responsible for progressive deterioration myocardial function observed in remain unclear may apoptosis (programmed cell death).We examined seven explanted hearts obtained during cardiac transplantation evidence apoptosis. All patients had severe chronic failure: four idiopathic dilated cardiomyopathy, three ischemic cardiomyopathy. DNA...
Intraplaque hemorrhage is common in advanced coronary atherosclerotic lesions. The relation between and the vulnerability of plaque to disruption may involve accumulation free cholesterol from erythrocyte membranes.
Background— Late stent thrombosis (LST) after Cypher and Taxus drug-eluting placement has emerged as a major concern. Although the clinical predictors of LST have been reported, specific morphological histological correlates remain unknown. Methods Results— From registry totaling 81 human autopsies stents, 46 (62 lesions) had implanted >30 days. We identified 28 lesions with thrombus compared those 34 similar duration without using computer-guided morphometric analyses. was defined an...
Background —Subclinical episodes of plaque disruption followed by healing are considered a mechanism increased burden. Detailed pathological studies healed ruptures, however, lacking. Methods and Results —We identified acute ruptures from 142 men who died sudden coronary death performed morphometric measurements burden, luminal stenosis, smooth muscle cell phenotype. Healed were found in 61% hearts associated with myocardial infarction, heart weight, dyslipidemia, diabetes. Multiple rupture...