A5024278402- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Aortic aneurysm repair treatments
- Cardiovascular Disease and Adiposity
- Lipoproteins and Cardiovascular Health
- Pulmonary Hypertension Research and Treatments
- Optical Coherence Tomography Applications
- Aortic Thrombus and Embolism
- Atherosclerosis and Cardiovascular Diseases
- Vascular Procedures and Complications
- Cardiac Arrhythmias and Treatments
- Congenital Heart Disease Studies
- Advanced X-ray and CT Imaging
- Adipokines, Inflammation, and Metabolic Diseases
- Venous Thromboembolism Diagnosis and Management
- Protease and Inhibitor Mechanisms
- Cardiovascular and Diving-Related Complications
- Cardiovascular Issues in Pregnancy
- Aortic Disease and Treatment Approaches
Kobe University
2016-2025
Aichi Medical University
2023
Onze Lieve Vrouwziekenhuis Hospital
2023
Emory University
2022
Southeast Georgia Health System
2022
Seoul National University Hospital
2021
Ministry of Health Labour and Welfare
2020
Clinical Research Management
2014-2019
Society of Interventional Radiology
2014-2019
Kobe University Hospital
2016
The purpose of this document is to make the output International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and Validation available medical scientific communities, through a peer-reviewed publication, in interest improving diagnosis treatment patients with atherosclerosis, including coronary artery disease. optical coherence tomography (IVOCT) catheter-based modality that acquires images at resolution ∼10 μm, enabling visualization blood vessel...
Since the intravascular ultrasound (IVUS) cannot detect neointimal layers in majority of sirolimus-eluting stents (SES) at chronic phase, it is still controversial to what extent SES remain uncovered. However, optical coherence tomography (OCT) with excellent resolution may be able thinner neointima.A total 34 patients (57 SES) underwent OCT and IVUS evaluations 6-month follow-up. The thickness neointima on each strut cross-section apposition vessel wall was evaluated. By evaluation, median...
Optical frequency domain imaging (OFDI) is a recently developed, light-based, high-resolution intravascular technique. Intravascular ultrasound (IVUS) widely used, conventional technique for guiding percutaneous coronary intervention (PCI). We aimed to demonstrate the non-inferiority of OFDI-guided PCI compared with IVUS-guided in terms clinical outcomes. did prospective, multicentre, randomized (ratio 1:1), active-controlled, study compare head-to-head OFDI vs. IVUS patients undergoing...
To evaluate the feasibility of combined use virtual histology (VH)-intravascular ultrasound (IVUS) and optical coherence tomography (OCT) for detecting in vivo thin-cap fibroatheroma (TCFA). In 56 patients with angina, 126 plaques identified by IVUS findings were analysed using both VH-IVUS OCT. IVUS-derived TCFA was defined as an abundant necrotic core (>10% cross-sectional area) contact lumen (NCCL) %plaque-volume >40%. OCT-derived a fibrous cap thickness <65 µm overlying low-intensity...
We performed this study to clarify natural consequences of abnormal structures (stent malapposition, thrombus, tissue prolapse, and stent edge dissection) after percutaneous coronary intervention (PCI). Thirty-five patients treated with 40 drug-eluting stents underwent serial optical coherence tomography (OCT) imaging immediately PCI at the 8-month follow-up. Among a total 73 929 struts in every frame, 431 (26 stents) showed malapposition PCI. these, 49 remained malapposed follow-up...
Adverse plaque characteristics (APCs) by coronary computed tomography (CT) angiography (CTA) are associated with myocardial ischaemia and future acute syndromes. The overall objective was to determine whether APCs on non-invasive CTA vulnerable features invasive optical coherence (OCT). Sixty-eight plaques in 45 patients were evaluated OCT. were: positive remodelling (PR), index ≥1.10; low attenuation (LAP), any intraplaque voxel <30 Hounsfield units; spotty calcification (SC), ≤3 mm;...
To assess the distribution of pressure and shear-related forces acting on atherosclerotic plaques their association with lesion characteristics using coronary CT angiography (cCTA)-based computational fluid dynamics (CFD) model epicardial arteries.Patient-specific models arteries were reconstructed from cCTA in 80 patients (12 women, 63.8±9.0 years). The wall shear stress (WSS) left anterior descending assessed CFD. High-risk defined as presence at least one following adverse plaque...
Low fractional flow reserve (FFR) values after percutaneous coronary intervention (PCI) carry a worse prognosis than high post-PCI FFR values. Therefore, the ability to predict might play an important role in procedural planning. Post-PCI can now be computed from pre-PCI tomography angiography (CTA) using derived revascularization planner (FFRCT Planner). The aim of this study was validate accuracy FFRCT Planner. In multicenter, investigator-initiated, prospective study, patients with...
The interplay between coronary hemodynamics and plaque characteristics remains poorly understood.The aim of this study was to compare atherosclerotic phenotypes focal diffuse artery disease (CAD) defined by hemodynamics.This multicenter, prospective, single-arm conducted in 5 countries. Patients with functionally significant lesions based on an invasive fractional flow reserve ≤0.80 were included. Plaque analysis performed using computed tomography angiography optical coherence tomography....
PurposeTo determine whether the inverted internal limiting membrane (ILM) flap technique contributes to high reattachment and closure rates in patients with macular hole-associated retinal detachment (MHRD).Patients methodsIn all, 15 eyes of MHRD undergoing 25-gauge pars plana vitrectomy ILM or peeling. The were divided into group (6 eyes) peeling (9 eyes). logarithm minimal angle resolution best-corrected visual acuity (BCVA) attachment hole compared between two groups before after...
The authors sought to clarify how intravascular ultrasound (IVUS) and optical coherence tomography affect percutaneous coronary intervention (PCI) with current-generation drug-eluting stents in a pre-specified substudy of the OPINION (OPtical frequency domain imaging versus INtravascular interventiON) trial, multicenter, prospective, randomized, noninferiority trial comparing (OFDI)-guided PCI IVUS-guided PCI.The impact these 2 modalities guiding remains unknown.Of 829 patients enrolled 106...
Background:In patients with acute coronary syndrome (ACS), alirocumab reduced the risk of recurring ischemic events. ODYSSEY J-IVUS assessed effect on atheroma volume in Japanese recently hospitalized ACS and hypercholesterolemia, using intravascular ultrasound imaging analysis.
Intravascular ultrasound (IVUS) was only rarely used in landmark trials comparing percutaneous coronary intervention (PCI) with artery bypass grafting (CABG) patients multivessel disease.The authors aimed to evaluate clinical outcomes after optimal IVUS-guided PCI undergoing PCI.The OPTIVUS (OPTimal IntraVascular UltraSound)-Complex study cohort a prospective multicenter single-arm enrolling 1,021 PCI, including left anterior descending using IVUS, aiming meet the prespecified criteria...