A5006779335- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Cardiac Valve Diseases and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Optical Coherence Tomography Applications
- Aortic aneurysm repair treatments
- Lipoproteins and Cardiovascular Health
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Atherosclerosis and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Cardiac Arrhythmias and Treatments
- Cardiac and Coronary Surgery Techniques
- Cardiac Structural Anomalies and Repair
- Venous Thromboembolism Diagnosis and Management
- Cardiovascular Health and Disease Prevention
- Coronary Artery Anomalies
- Cancer Treatment and Pharmacology
- Blood Pressure and Hypertension Studies
- Vascular Procedures and Complications
- Integrated Circuits and Semiconductor Failure Analysis
- Infective Endocarditis Diagnosis and Management
Saint Camillus International University of Health and Medical Sciences
2020-2024
Azienda Ospedaliera San Giovanni Addolorata
2015-2024
International Flame Research Foundation
2024
Agostino Gemelli University Polyclinic
2022-2023
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2023
Università Campus Bio-Medico
2023
Ospedale Santa Maria Goretti
2021-2023
Centro Cardiologico Monzino
2016-2023
Azienda Ospedaliera G. Brotzu
2016-2023
Institute for Scientific Interchange
2010-2023
The purpose of this document is to make the output International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and Validation available medical scientific communities, through a peer-reviewed publication, in interest improving diagnosis treatment patients with atherosclerosis, including coronary artery disease. optical coherence tomography (IVOCT) catheter-based modality that acquires images at resolution ∼10 μm, enabling visualization blood vessel...
This Consensus Document is the first of two reports summarizing views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI) on clinical use intracoronary imaging including intravascular ultrasound (IVUS) and optical coherence tomography (OCT). The document appraises role to guide percutaneous coronary interventions (PCIs) in practice. Current evidence regarding impact guidance cardiovascular outcomes summarized, patients or lesions most likely...
This document is complementary to an Expert Review Document on Optical Coherence Tomography (OCT) for the study of coronary arteries and atherosclerosis.1 The goal this companion manuscript provide a practical guide framework appropriate use reporting novel frequency domain (FD) OCT imaging interventional procedures, with particular interest comparison intravascular ultrasound (IVUS).1–4 In Atherosclerosis, comprehensive description physical principles time (TD) catheters (St Jude Medical,...
Angiographic guidance for percutaneous coronary intervention (PCI) has substantial limitations. The superior spatial resolution of optical coherence tomography (OCT) could translate into meaningful clinical benefits. We aimed to compare angiographic alone versus plus OCT PCI.Patients undergoing PCI with (OCT group) were compared matched patients only (Angio within 30 days. primary endpoint was the one-year rate cardiac death or myocardial infarction (MI). A total 670 included, 335 in group...
Abstract Aims The CLIMA study, on the relationship between coronary plaque morphology of left anterior descending artery and twelve months clinical outcome, was designed to explore predictive value multiple high-risk features in same lesion [minimum lumen area (MLA), fibrous cap thickness (FCT), lipid arc circumferential extension, presence optical coherence tomography (OCT)-defined macrophages] as detected by OCT. Composite cardiac death target segment myocardial infarction primary...
Patients presenting with acute coronary syndrome (ACS) may have different plaque morphologies at the culprit lesion. In particular, rupture (PR) has been shown as more frequent morphology in ACS. However, its prognostic value is still unknown. this study, we evaluated of PR, compared intact fibrous cap (IFC), patients We enrolled consecutive admitted to our Coronary Care Unit for ACS and undergoing angiography followed by interpretable optical coherence tomography (OCT) imaging. Culprit...
This consensus document is the second of two reports summarizing views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI) on clinical use intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance stent selection optimization deployment, invasive facilitates angiographic interpretation may guide treatment in acute coronary syndrome....
Background Little clinical research on new-generation heat-not-burn cigarettes ( HNBC ) in comparison with electronic vaping EVC and traditional tobacco combustion TC has been reported. We aimed to appraise the acute effects of single use , EVC, healthy smokers. Methods Results This was an independent, cross-over, randomized trial 20 smokers, allocation different cycles . All participants used all types products, intercycle washout 1 week. End points were oxidative stress, antioxidant...
No information is available on the long-term results of radial artery (RA) grafts used as coronary bypass conduits.In this report, we describe (105+/-9 months) angiographic a series 90 consecutive patients in whom RA was conduit directly anastomosed to ascending aorta. The patency and perfect rates were 91.6% 88%, respectively, versus 97.5% 96.3% for internal thoracic grafts. severity stenosis target vessel clearly influenced patency, whereas location use calcium channel blockers did not...
Background— Systemic levels of myeloperoxidase predict prognosis in patients with acute coronary syndromes and are considered a marker plaque vulnerability. It is not known whether associated different morphologies (ie, rupture or erosion the culprit lesion) syndrome. Methods Results— Twenty-five consecutive (aged 67±11 years; 15 men [60%]; 13 [52%] non–ST-segment elevation syndrome 12 [48%] ST-segment myocardial infarction) were enrolled. Optical coherence tomography classified lesion as...
Myocardial necrosis can occur during percutaneous coronary intervention (PCI) despite optimal adjunctive pharmacology and careful technique. We investigated the mechanisms of procedural infarction using angiographic analysis, intravascular ultrasound, delayed-enhancement magnetic resonance imaging.Fifty-two patients (64 vessels) who underwent complex PCI were studied. All preloaded with clopidogrel received glycoprotein IIb/IIIa inhibitors. "Adjacent" myonecrosis was defined as presence an...
This Consensus Document is the first of two reports summarizing views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI) on clinical use intracoronary imaging including intravascular ultrasound (IVUS) and optical coherence tomography (OCT). The document appraises role to guide percutaneous coronary interventions (PCIs) in practice. Current evidence regarding impact guidance cardiovascular outcomes summarized, patients or lesions most likely...
Optical coherence tomography (OCT) is a light-based intracoronary imaging modality that provides high-resolution cross-sectional images of the luminal and plaque morphology. Currently, segmentation OCT identification composition are mainly performed manually by expert observers. However, this process laborious time consuming its accuracy relies on expertise observer. To address these limitations, we present methodology able to data in fully automated fashion. The proposed detect lumen...
At one end of the coronary artery disease (CAD) spectrum, there are patients with multiple recurrent acute syndromes (rACS), and at other those long-standing clinical stability. Predicting natural history these is challenging because unstable plaques often heal without resulting in ACS.To assess vivo atherosclerotic phenotype as well prevalence characteristics healed by optical coherence tomography (OCT) imaging extremes CAD spectrum.This an observational, single-center cohort study...
Aims: Randomised trials have demonstrated improvement in clinical outcomes with intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) compared angiography-guided PCI. The ILUMIEN III trial non-inferiority of an optical coherence tomography (OCT)- versus IVUS-guided PCI strategy achieving similar post-PCI lumen dimensions. IV is a large-scale, multicentre, randomised designed to demonstrate the superiority OCT- stent implantation patients high-risk characteristics...
Background: Technological advances in arterial wall imaging permit the opportunity to visualize coronary atherosclerotic plaque with sufficient resolution characterize both its burden and compositional phenotype.These modalities have been used extensively clinical trials evaluate impact of lipid lowering therapies on serial changes disease burden.While findings unequivocally established that these interventions capacity either slow progression or promote regression, depending degree...
Background —The aim of this study was to evaluate the relationship between residual plaque burden after coronary stent implantation and development late in-stent neointimal proliferation. Methods Results —Between January 1996 May 1997, 50 patients underwent intravascular ultrasound (IVUS) interrogation at 6±1.2 months in native arteries. IVUS images were acquired with a motorized pullback, cross-sectional measurements performed within stents 1-mm intervals. The following obtained: (1) lumen...