Eloisa Arbustini
A5001978486- Cardiomyopathy and Myosin Studies
- Viral Infections and Immunology Research
- Cardiovascular Effects of Exercise
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Transplantation: Methods and Outcomes
- Cardiovascular Function and Risk Factors
- Connective tissue disorders research
- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Nuclear Structure and Function
- RNA Research and Splicing
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiac electrophysiology and arrhythmias
- Acute Myocardial Infarction Research
- Cerebrovascular and Carotid Artery Diseases
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Mitochondrial Function and Pathology
- Aortic aneurysm repair treatments
- Renal Transplantation Outcomes and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Organ Transplantation Techniques and Outcomes
- COVID-19 Clinical Research Studies
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Baylor University Medical Center
2015-2024
Policlinico San Matteo Fondazione
2015-2024
University of Pavia
2012-2023
Azienda Ospedaliera San Giovanni Addolorata
2014-2023
Ospedale Santa Maria Goretti
2023
Agostino Gemelli University Polyclinic
2023
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2023
Azienda Ospedaliera G. Brotzu
2023
Centro Cardiologico Monzino
2023
In this position statement of the ESC Working Group on Myocardial and Pericardial Diseases an expert consensus group reviews current knowledge clinical presentation, diagnosis treatment myocarditis, proposes new diagnostic criteria for clinically suspected myocarditis its distinct biopsy-proven pathogenetic forms.The aims are to bridge gap between tissue-based diagnosis, improve management provide a common reference point future registries multicentre randomised controlled trials...
In biology, classification systems are used to promote understanding and systematic discussion through the use of logical groups hierarchies. clinical medicine, similar principles standardise nomenclature disease. For more than three decades, heart muscle diseases have been classified into primary or idiopathic myocardial (cardiomyopathies) secondary disorders that morphological appearances, but which caused by an identifiable pathology such as coronary artery disease infiltration (specific...
Apoptosis has been shown to contribute loss of cardiomyocytes in cardiomyopathy, progressive decline left ventricular function, and congestive heart failure. Because the molecular mechanisms involved apoptosis cardiocytes are not completely understood, we studied biochemical ultrastructural characteristics upstream regulators hearts explanted from patients undergoing transplantation. Sixteen transplantation were by electron microscopy or immunoblotting detect release mitochondrial cytochrome...
Numerous genes are known to cause dilated cardiomyopathy (DCM). However, until now technological limitations have hindered elucidation of the contribution all clinically relevant disease DCM phenotypes in larger cohorts. We utilized next-generation sequencing overcome these and screened a large cohort. In this multi-centre, multi-national study, we enrolled 639 patients with sporadic or familial DCM. To samples, applied standardized protocol for ultra-high coverage 84 genes, leading 99.1%...
Advances in molecular genetics present new opportunities and challenges for cardiologists who manage patients families with cardiomyopathies. The aims of this position statement the European Society Cardiology Working Group on Myocardial Pericardial Diseases are to review general issues related genetic counselling, family screening testing a cardiomyopathy, provide key messages suggestions clinicians involved their management.
<h3>OBJECTIVE</h3> To evaluate the prevalence of plaque erosion as a substrate for coronary thrombosis. <h3>DESIGN</h3> Pathological study in patients with acute myocardial infarction not treated thrombolysis or interventional procedures. <h3>PATIENTS</h3> 298 consecutive (189 men, mean (SD) age 66 (11) years; 109 women, 74 (8) years) dying hospital between 1984 and 1996 from infarction, diagnosed by ECG changes rise cardiac enzymes. <h3>MAIN OUTCOME MEASURES</h3> Histopathological...
In 2008, The ESC Working Group on Myocardial and Pericardial Diseases proposed an updated classification of cardiomyopathies based morphological functional phenotypes subcategories familial/genetic non-familial/non-genetic disease. this position statement, we propose a framework for the clinical approach to diagnosis in recognition diagnostic 'red flags' that can be used guide rational selection specialized tests including genetic analysis. basic premise is adoption cardiomyopathy-specific...
This document is complementary to an Expert Review Document on Optical Coherence Tomography (OCT) for the study of coronary arteries and atherosclerosis.1 The goal this companion manuscript provide a practical guide framework appropriate use reporting novel frequency domain (FD) OCT imaging interventional procedures, with particular interest comparison intravascular ultrasound (IVUS).1–4 In Atherosclerosis, comprehensive description physical principles time (TD) catheters (St Jude Medical,...
Dilated cardiomyopathy (DCM) is a major cause of heart failure with high familial recurrence risk. So far, the genetics DCM remains largely unresolved. We conducted first genome-wide association study (GWAS) to identify loci contributing sporadic DCM. One thousand one hundred and seventy-nine patients 1108 controls contributed discovery phase. Pools DNA stratified on disease status, population, age, gender were constituted used for testing 517 382 single nucleotide polymorphisms (SNPs)....
Abstract Aims The CLIMA study, on the relationship between coronary plaque morphology of left anterior descending artery and twelve months clinical outcome, was designed to explore predictive value multiple high-risk features in same lesion [minimum lumen area (MLA), fibrous cap thickness (FCT), lipid arc circumferential extension, presence optical coherence tomography (OCT)-defined macrophages] as detected by OCT. Composite cardiac death target segment myocardial infarction primary...