A5079881065- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Valve Diseases and Treatments
- Vascular Procedures and Complications
- Cerebrovascular and Carotid Artery Diseases
- Antiplatelet Therapy and Cardiovascular Diseases
- Infective Endocarditis Diagnosis and Management
- Venous Thromboembolism Diagnosis and Management
- Peripheral Artery Disease Management
- Aortic aneurysm repair treatments
- Atrial Fibrillation Management and Outcomes
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Structural Anomalies and Repair
- Cardiovascular Function and Risk Factors
- Aortic Disease and Treatment Approaches
- Cardiac Health and Mental Health
- Cardiac Arrhythmias and Treatments
- Central Venous Catheters and Hemodialysis
- Coronary Artery Anomalies
- Acute Kidney Injury Research
- Cardiac Arrest and Resuscitation
- Optical Coherence Tomography Applications
- Blood Pressure and Hypertension Studies
- Mechanical Circulatory Support Devices
Agostino Gemelli University Polyclinic
2012-2025
Istituti di Ricovero e Cura a Carattere Scientifico
2016-2025
Università Cattolica del Sacro Cuore
2010-2025
Ca' Foncello Hospital
2024
Azienda Ospedaliera San Giovanni Addolorata
2015-2023
Ospedale Santa Maria Goretti
2023
Azienda Ospedaliero-Universitaria Policlinico - Vittorio Emanuele
2023
Azienda Ospedaliera G. Brotzu
2016-2023
Centro Cardiologico Monzino
2016-2023
University of Rome Tor Vergata
2012-2022
Abstract Aims The CLIMA study, on the relationship between coronary plaque morphology of left anterior descending artery and twelve months clinical outcome, was designed to explore predictive value multiple high-risk features in same lesion [minimum lumen area (MLA), fibrous cap thickness (FCT), lipid arc circumferential extension, presence optical coherence tomography (OCT)-defined macrophages] as detected by OCT. Composite cardiac death target segment myocardial infarction primary...
Journal Article Functional coronary assessment in angina with intermediate stenosis: the #FullPhysiology approach Get access Antonio Maria Leone, Leone Center of Excellence Cardiovascular Sciences, Ospedale Isola Tiberina—Gemelli Isola, Via di Ponte Quattro Capi 39, 00186 Rome, ItalyUniversità Cattolica del Sacro Cuore, Largo Agostino Gemelli 1, 00168 Italy Corresponding author. Email: [email protected], protected] https://orcid.org/0000-0002-1276-9883 Search for other works by this author...
Background Myocardial bridging (MB) may represent a cause of myocardial ischemia in patients with non-obstructive coronary artery disease (NOCAD). Herein, we assessed the interplay between MB and vasomotor disorders, also evaluating their prognostic relevance infarction arteries (MINOCA) or stable NOCAD. Methods Results We prospectively enrolled NOCAD undergoing intracoronary acetylcholine provocative test. The incidence major adverse cardiac events, defined as composite death, non-fatal...
Intracoronary provocation testing with acetylcholine (ACh) is crucial for the diagnosis of functional coronary alterations in patients suspected myocardial ischaemia and non-obstructive arteries.Our intention was to assess safety predictive value major adverse cardiovascular cerebrovascular events (MACCE) presenting arteries (INOCA) or infarction (MINOCA).We prospectively enrolled consecutive INOCA MINOCA undergoing intracoronary ACh testing.A total 317 were enrolled: 174 (54.9%) 143 (45.1%)...
Current evidence on the long-term outcome and its determinants in patients with unprotected left main trifurcation (LMT) treated percutaneous coronary intervention (PCI) is based small-sized studies. We aimed to assess clinical, anatomical procedural factors impacting clinical outcomes of LMT by PCI. conducted a multicenter retrospective study consecutive stable or acute settings who underwent PCI drug-eluting-stent implantation. Primary endpoint was major adverse cardiovascular events...
To date, no common risk stratification system is available to predict the of surgical or percutaneous myocardial revascularisation in patients with coronary artery disease (CAD). Thus, we sought assess European System for Cardiac Operative Risk Evaluation (EuroSCORE) validity in-hospital mortality after intervention (PCI).EuroSCORE was prospectively and systematically assessed 1173 consecutive undergoing PCI a high-volume single centre between April 2005 October 2006.The receiver-operating...
Abstract Objectives: To describe a novel modification of the T‐stenting technique and to report bench test as well first clinical results obtained. Background: The best treat bifurcated coronary lesions has not been defined. Methods: This is based, after stenting main vessel (MV) kissing balloon, on intentional minimal protrusion side‐branch (SB) stent within MV. Final balloon performed using kept uninflated into MV before SB stenting. was tested in vitro applied two independent series...
Vulnerable plaques are characterized by a high macrophage content. We investigated the optical coherence tomography (OCT) capability of identifying coronary plaque presence using tissue property indexes.Fifteen epicardial arteries were imaged OCT and subsequently analysed histology. Correlating OCT-histological sections identified regions interest (ROIs) selected on both atherosclerotic normal appearing vessel tracts. OCT-derived indexes named normalized standard deviation (NSD), signal...
Background— Clinical consequences of optical coherence tomographic (OCT) high-definition visualization plaque/stent structures in acute patients remain undefined. In this retrospective substudy, we assessed the prognostic impact postprocedural culprit lesion OCT findings with coronary syndrome undergoing percutaneous intervention. Methods and Results— CLI-OPCI (Centro per la Lotta Contro L’Infarto-Optimization Percutaneous Coronary Intervention) database collecting cases from 5 independent...