A5059810481- Coronary Interventions and Diagnostics
- Vascular Procedures and Complications
- Cardiac Imaging and Diagnostics
- Peripheral Artery Disease Management
- Central Venous Catheters and Hemodialysis
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Renal and Vascular Pathologies
- Cerebrovascular and Carotid Artery Diseases
- Aortic aneurysm repair treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Atrial Fibrillation Management and Outcomes
- Cardiovascular and Diving-Related Complications
- Cardiovascular Function and Risk Factors
- Congenital Heart Disease Studies
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- Coronary Artery Anomalies
- Retinal and Optic Conditions
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cardiac and Coronary Surgery Techniques
- Acute Kidney Injury Research
- Intracranial Aneurysms: Treatment and Complications
- Radiation Dose and Imaging
Azienda Ospedaliera Sant'Andrea
2021-2024
CTO Andrea Alesini
2021-2024
Sapienza University of Rome
2023
Università Cattolica del Sacro Cuore
2008-2014
Catholic University of America
2008-2013
University of the Sacred Heart
2013
Interventional cardiologists have recently become increasingly entrusted with the treatment of frail patients complex coronary anatomy. Additionally, calcified lesions (CLs) more common due to continued increase in older population worldwide, increasing need for simpler options such lesions. Hence, numerous debulking tools been developed overcome difficulties associated angioplasty CLs and optimize stent positioning delivery. In addition, bifurcation (BLs) always challenging than other...
Transradial access reduces the incidence of site complications percutaneous revascularization procedures. However, in patients with peripheral vascular disease, adoption transradial approach for superficial femoral artery (SFA) angioplasty is usually prevented by distance between and target lesions; thus, SFA commonly performed transfemoral approach. Recently, low-profile balloons extended shaft length became available, allowing to potentially address lesions As plain balloon represents a...
To assess the impact of an "operative" classification vascular anatomic variants on feasibility trans-radial approach.Vascular located from wrist to aorta may influence procedures. Recently, a new these was proposed.Consecutive diagnostic or interventional catheterizations were considered. Vascular classified according 10 categories and sub-grouped ABC (A: radial-brachial arterial axis; B: axillary-subclavian-anonymous C: aortic arch). Primary study end-point failure approach (necessity...
Trans-radial approach (TRA) reduces vascular access-site complications but has some technical limitations. Usually, TRA procedures are performed using 5 Fr or 6 sheaths, whereas complex interventions requiring larger sheaths approached by trans-femoral access.During 4 years, at two Institutions with high use, we have attempted to perform selected coronary peripheral than Fr. Clinical and procedural data were prospectively collected. Attempt place a 7 8 sheath (according the planned strategy...
Percutaneous revascularization of superficial femoral artery (SFA) is increasingly carried out to treat patients with peripheral vascular disease and either intermittent claudication or critical limb ischemia. Transradial access adopted for invasive procedures due reduced access-site complications improved patient's comfort, compared transfemoral. However, coronary interventions, the adoption transradial in limited. Concerning SFA usually prevented by distance between target lesion, which...
Background: in patients undergoing percutaneous coronary interventions (PCI), radial access should be favoured over femoral as it reduces the risk of vascular complications and bleeding. Furthermore, a preventive role occurrence acute kidney injury (AKI), mainly mediated by reduction bleeding cholesterol crystal embolization into renal circulation, has been investigated several studies, yielding conflicting results. Methods: we designed retrospective study to appraise effect use site on AKI...
Objective Transradial access for coronary angiography may offer some advantages in comparison with conventional transfemoral specific subgroups of patients. Therefore, the aim this study was to compare transradial and approaches patients previous artery bypass graft (CABG) surgery using left internal mammary (IMA). Methods The time IMA cannulation, needed evaluation, total procedure were compared 60 previously submitted CABG IMA. homolateral radial attempted 20 consecutive (TR group),...
To prospectively assess the impact of post-procedural side-branch (SB) stenosis on inducible myocardial ischemia in patients with bifurcated lesions undergoing percutaneous interventions.Provisional-stenting drug-eluting stents (DES) is recommended strategy to treat percutaneously but associated variable degrees residual SB stenosis. The role uncertain.Patients bifurcations treated by DES according provisional-stenting technique were enrolled study if they had no other untreated lesion....
The efficacy of trans-radial approach (TRA) in chronic total occlusions (CTO) percutaneous coronary interventions (PCI) is not well established. Thus, we sought to review the feasibility and long-term results TRA for CTO PCI performed by dedicated operatorsof our center.CTO radialists were considered. Primary end-points "PCI success" (stent implantation with residual stenosis < 20% TIMI 3) "patient (PCI success a first or second attempt). Vascular complications major adverse cardiac events...
Neointimal hyperplasia plays a pivotal role in the pathogenesis of in-stent restenosis patients undergoing percutaneous coronary interventions. Drug-eluting balloons are promising tool to prevent after angioplasty. Moreover, an increased knowledge pathophysiology my help improve therapeutic strategies. We present design open-label, randomized three-arm clinical trial aimed assess whether strategy bare-metal stent implantation with additional use drug-eluting balloons, either before...
Polymer-coating represents a key component of drug-eluting stent (DES) technology and its possible impact on vessel-wall healing is matter debate. The clinical different polymer-coating may be assessed by comparing the outcome patients treated DES having same platform drug, differing in polymer. Thus, we compared Endeavor Zotarolimus-eluting (E-ZES) Resolute (R-ZES) as they differ only.At our Institution, E-ZES was available during first period then it substituted R-ZES second period....
To investigate the role of renal stenting in selected patients with chronic ischemic heart disease and artery stenosis.Consecutive patients, severe hypertension and/or impaired function undergoing stenting, were prospectively enrolled. Mid-term (at least 2 years) follow-up was performed to assess both changes [serum creatinine estimated glomerular filtrate rate (eGFR)] blood pressure (BP) control (number required drugs) record incidence clinical major adverse events. Moreover, first...
Restenosis and bifurcated lesions represent technically challenging for percutaneous coronary interventions (PCI). Data regarding procedural clinical outcome of re-PCI restenosis stented are lacking. Our aims were to evaluate angiographic results one-year PCI lesions.Consecutive patients undergoing one lesion previously treated by stent implantation at our centre entered the study. The primary endpoint was success, defined as final residual stenosis ≤30% in main vessel with TIMI 3 flow both...