Antonio Zingarelli
A5008911822- Vascular Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Acute Myocardial Infarction Research
- Cardiovascular Issues in Pregnancy
- Central Venous Catheters and Hemodialysis
- Coronary Interventions and Diagnostics
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Cardiac Health and Mental Health
- Ultrasound in Clinical Applications
- Coronary Artery Anomalies
- Takotsubo Cardiomyopathy and Associated Phenomena
- Acute Kidney Injury Research
- Peptidase Inhibition and Analysis
- Peripheral Artery Disease Management
- Cardiac Imaging and Diagnostics
- Neurosurgical Procedures and Complications
- Kawasaki Disease and Coronary Complications
- Radiation Dose and Imaging
- Electroconvulsive Therapy Studies
- Cardiac tumors and thrombi
- Vascular anomalies and interventions
Ospedale Policlinico San Martino
2011-2024
University of Genoa
2014-2017
Azienda Ospedaliera Universitaria Policlinico "G. Martino"
2015
Conflicting evidence exists on the efficacy and safety of bivalirudin administered as part percutaneous coronary intervention (PCI) in patients with an acute syndrome.We randomly assigned 7213 syndrome for whom PCI was anticipated to receive either or unfractionated heparin. Patients group were subsequently not a post-PCI infusion. Primary outcomes comparison between heparin occurrence major adverse cardiovascular events (a composite death, myocardial infarction, stroke) net clinical...
To test the optimal antithrombotic regimen in patients with acute coronary syndrome. Randomised controlled trial. Patients syndrome and without ST segment elevation 78 centres Italy, Netherlands, Spain, Sweden. 7213 planned percutaneous intervention: 4010 3203 elevation. The primary study results overall population have been reported previously. were randomly assigned, an open label fashion, to one of two regimens: bivalirudin glycoprotein IIb/IIIa inhibitors restricted procedural...
Background: The optimal management of patients with spontaneous coronary artery dissection remains debated. Methods: Patients enrolled in the DISCO (Dissezioni Spontanee Coronariche) Registry up to December 2020 were included. primary end point was major adverse cardiovascular events, a composite all-cause death, nonfatal myocardial infarction, and repeat percutaneous intervention (PCI). Independent predictors PCI medical investigated. Results: Among 369 patients, 129 (35%) underwent PCI,...
Objectives To assess the late outcome of Tako-Tsubo like syndrome in a community hospital northern Italy. Methods and results We reviewed 2233 patients who were admitted from 2001 to 2006 with diagnosis acute coronary syndrome. Twenty-two (1%) presenting clinical instrumental characteristics included study prospectively underwent echocardiographic follow-up. All women; aged 76 ± 7 years; 82% experienced stress before episode; 50% reported chest pain dyspnoea also days before. Mean troponin...
Abstract Aims The role of coronary calcification on clinical outcomes among different revascularization strategies in patients presenting with acute syndromes (ACSs) has been rarely investigated. aim this investigation is to evaluate the calcification, detected by angiography, whole spectrum ACS. Methods and results present study was a post hoc analysis MATRIX programme. primary endpoint major adverse cardiovascular events (MACE), defined as composite all-cause mortality, myocardial...
Spontaneous coronary artery dissection (SCAD) is a relevant non-atherosclerotic cause of acute syndrome with complex genetic architecture. Recent discoveries have highlighted the potential role miRNAs and protein-coding genes involved in processing small RNAs pathogenesis SCAD. Furthermore, there may be connection between SCAD increased cardiovascular risk observed fragile X premutation carriers as well correlation pathogenetic variants encoding for collagen extracellular matrix, which are...
The recent widespread adoption of radial access in performing percutaneous coronary interventions has determined a greater reduction vascular complications and related bleedings than traditional femoral access, even leading to favourable impact on clinical outcome through significant combined efficacy safety end-point large randomised trial (1). Besides, the progressive diffusion slender approach with dedicated sheaths small diameter catheters have almost always allowed accomplish procedures...
Background. Anatomical abnormalities (caliber and course) of radial artery are a potential limiting factor for diagnostic interventional coronary procedures performed through the transradial approach. In these circumstances, prompt careful angiographic assessment anatomy is crucial after sheath insertion in order to minimize risk vascular complications or access failure. Two case reports high origin (from axillary artery) described. After brief review anatomical classification this...
Abstract Aims Whether patients with spontaneous coronary artery dissection (SCAD) should undergo an initial conservative management or immediate revascularization through percutaneous intervention (PCI) remains debated. To investigate the frequency and predictors of choosing a strategy PCI for SCAD, to compare clinical outcomes those undergoing medical management. Methods results 369 enrolled in multicentre international DIssezioni Spontanee COronariche (DISCO) registry between January 2009...