- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Acute Myocardial Infarction Research
- Optical Coherence Tomography Applications
- Aortic aneurysm repair treatments
- Photoacoustic and Ultrasonic Imaging
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiovascular Disease and Adiposity
- Atherosclerosis and Cardiovascular Diseases
- Cardiac and Coronary Surgery Techniques
- Vascular Procedures and Complications
- Cardiovascular Health and Disease Prevention
- Cardiac tumors and thrombi
- Venous Thromboembolism Diagnosis and Management
- Coronary Artery Anomalies
- Cardiac Arrhythmias and Treatments
- Advanced MRI Techniques and Applications
- Ultrasound and Hyperthermia Applications
- Integrated Circuits and Semiconductor Failure Analysis
- Renal and Vascular Pathologies
- Aortic Thrombus and Embolism
- Cardiac Structural Anomalies and Repair
Ludwig-Maximilians-Universität München
1997-2023
University Hospital of Zurich
2017-2023
LMU Klinikum
2021
Erasmus MC
2011-2020
Erasmus University Rotterdam
2011-2020
Massachusetts General Hospital
2010-2020
University of Zurich
2018
University Medical Center
2017
Institut Cardiovasculaire Paris Sud
2002-2017
Générale de Santé
2017
The purpose of this document is to make the output International Working Group for Intravascular Optical Coherence Tomography (IWG-IVOCT) Standardization and Validation available medical scientific communities, through a peer-reviewed publication, in interest improving diagnosis treatment patients with atherosclerosis, including coronary artery disease. optical coherence tomography (IVOCT) catheter-based modality that acquires images at resolution ∼10 μm, enabling visualization blood vessel...
This Consensus Document is the first of two reports summarizing views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI) on clinical use intracoronary imaging including intravascular ultrasound (IVUS) and optical coherence tomography (OCT). The document appraises role to guide percutaneous coronary interventions (PCIs) in practice. Current evidence regarding impact guidance cardiovascular outcomes summarized, patients or lesions most likely...
This consensus document, a summary of the views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI), appraises importance ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% patients undergoing invasive angiography do not have obstructive artery disease, more common in women than men, and large proportion INOCA as cause their symptoms. present wide spectrum...
Background— The impact of drug-eluting stent (DES) implantation on the incidence major adverse cardiovascular events in patients undergoing percutaneous intervention for left main (LM) coronary disease is largely unknown. Methods and Results— From April 2001 to December 2003, 181 underwent LM stenosis at our institution. first cohort consisted 86 (19 protected LM) treated with bare metal stents (pre-DES group); second comprised 95 (15 exclusively DES. 2 cohorts were well balanced all...
Acute coronary syndromes (ACS) are mostly caused by plaque rupture. This study aims to investigate the prognostic value of in vivo detection high-risk plaques intravascular ultrasound (IVUS) patients undergoing angiography. Between November 2008 and January 2011, IVUS a non-culprit artery was performed 581 who underwent angiography for ACS (n = 318) or stable angina 263). Primary endpoint major adverse cardiac events (MACEs) defined as mortality, ACS, unplanned revascularization. Culprit...
Background— With the use of optical coherence tomography (OCT), alterations reflectance characteristics everolimus-eluting bioresorbable vascular scaffold (BVS) struts have been reported in humans. In absence histology, interpretation appearances by OCT remains speculative. We therefore report findings with corresponding histology porcine coronary artery model immediately after and at 28 days 2, 3, 4 years BVS implantation. Methods Results— Thirty-five polymeric (3.0×12.0 mm) were singly...
Background— The first generation of the bioresorbable everolimus drug-eluting vascular scaffold showed signs shrinkage at 6 months, which largely contributed to late luminal loss. Nevertheless, loss was less than that observed with bare metal stents. To maintain mechanical integrity device up design and manufacturing process its polymer were modified. Methods Results— Quantitative coronary angiography, intravascular ultrasound analysis radiofrequency backscattering, as an optional...
This consensus document is the second of two reports summarizing views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI) on clinical use intracoronary imaging including intravascular ultrasound (IVUS), optical coherence tomography (OCT), and near infrared spectroscopy (NIRS)-IVUS. Beyond guidance stent selection optimization deployment, invasive facilitates angiographic interpretation may guide treatment in acute coronary syndrome....
This consensus document, a summary of the views an expert panel organized by European Association Percutaneous Cardiovascular Interventions (EAPCI), appraises importance ischaemia with non-obstructive coronary arteries (INOCA). Angina pectoris affects approximately 112 million people globally. Up to 70% patients undergoing invasive angiography do not have obstructive artery disease, more common in women than men, and large proportion INOCA as cause their symptoms. present wide spectrum...
The first clinical study of paclitaxel-eluting stent for de novo lesions showed promising results. We performed the TAXUS III trial to evaluate feasibility and safety treatment in-stent restenosis (ISR).The was a single-arm, 2-center that enrolled 28 patients with ISR meeting criteria lesion length < or =30 mm, 50% 99% diameter stenosis, vessel 3.0 3.5 mm. They were treated one more NIRx stents. Twenty-five completed angiographic follow-up at 6 months, 17 these underwent intravascular...
Optical coherence tomography (OCT) is rapidly becoming the method of choice for assessing arterial wall pathology in vivo. Atherosclerotic plaques can be diagnosed with high accuracy, including measurement thickness fibrous caps, enabling an assessment risk rupture. While OCT image presents morphological information highly resolved detail, it relies on interpretation images by trained readers identification vessel components and tissue type. We present a framework to enable systematic...
Restenosis remains the major limitation of coronary catheter-based intervention. In small vessels, amount neointimal tissue is disproportionately greater than vessel caliber, resulting in higher restenosis rates. Randomized Study With Sirolimus-Eluting Bx Velocity Balloon-Expandable Stent (RAVEL) trial, approximately 40% vessels were (<2.5 mm). The present study evaluates relationship between angiographic outcome and diameter for sirolimus-eluting stents.Patients randomized to receive either...
Background — Observational studies in selected patients have shown remarkably low restenosis rates after ultrasound-guided stent implantation. However, it is unknown whether this implantation strategy improves long-term angiographic and clinical outcome routine practice. Methods Results A total of 550 with a symptomatic coronary lesion or silent ischemia were randomly assigned to either angiography-guided ≤2 tubular stents. The primary end points dichotomous rate, minimal lumen diameter,...