- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Arrhythmias and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Rate Variability and Autonomic Control
- Acute Myocardial Infarction Research
- Atrial Fibrillation Management and Outcomes
- Cerebrovascular and Carotid Artery Diseases
- Lipoproteins and Cardiovascular Health
- Cardiac Valve Diseases and Treatments
- Cardiac electrophysiology and arrhythmias
- Peripheral Artery Disease Management
- Cardiovascular Health and Disease Prevention
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
- Cardiovascular Disease and Adiposity
- Pharmaceutical Economics and Policy
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Vascular Procedures and Complications
- Optical Coherence Tomography Applications
- Cardiovascular and exercise physiology
- Venous Thromboembolism Diagnosis and Management
- Non-Invasive Vital Sign Monitoring
- Hormonal Regulation and Hypertension
Kosin University Gospel Hospital
2015-2025
Kosin University
2013-2023
Novartis (United States)
2020
Ajou University
2017
Florida Atlantic University
2017
Busan Medical Center
2016
Yonsei University
2015
Erasmus University Rotterdam
2011-2014
Erasmus MC
2011-2014
Korea University
2014
Acute coronary syndromes (ACS) are mostly caused by plaque rupture. This study aims to investigate the prognostic value of in vivo detection high-risk plaques intravascular ultrasound (IVUS) patients undergoing angiography. Between November 2008 and January 2011, IVUS a non-culprit artery was performed 581 who underwent angiography for ACS (n = 318) or stable angina 263). Primary endpoint major adverse cardiac events (MACEs) defined as mortality, ACS, unplanned revascularization. Culprit...
To analyse the vasoreactivity of a coronary segment, previously scaffolded by ABSORB bioresorbable vascular scaffold (BVS) device, in relationship to its intravascular ultrasound-virtual histology (IVUS-VH) composition and reduction greyscale echogenicity struts. Coronary segments, transiently polymeric may long-term recover normal vasomotor tone. Recovery endothelial-dependent vasomotion be enabled bioresorption, underlying tissue, or combination both mechanisms.All patients from Cohort A B...
Importance Discontinuation of oral anticoagulant treatment is common in clinical practice due to concerns about bleeding, even for procedures with minimal low bleeding risk. Objective To explore whether perioperative discontinuation factor Xa inhibitors associated major and thromboembolic events patients atrial fibrillation (AF) undergoing Design, Setting, Participants This prospective, multicenter, single-arm cohort study conducted Korea included AF who planned undergo a procedure risk...
There are limited randomized studies on patients undergoing multi-vessel percutaneous coronary intervention (PCI) comparing the outcomes between stent thickness and polymer types. To compare clinical of thick biodegradable polymer-based biolimus A9-eluting stents (BESs) thin durable zotarolimus-eluting (ZESs) in PCI. A total 936 who underwent artery stenting were randomly assigned to BES (n=472) or ZES (n=464) groups. The primary endpoint was 2-year major adverse cardiac events (MACEs), a...
Find out more about this article on The CABG SYNTAX Score - an angiographic tool to grade the complexity of coronary disease following artery bypass graft surgery: from Left Main Angiographic (SYNTAX-LE MANS) substudy
Angiographic evidence of edge dissections has been associated with a risk early stent thrombosis. Optical coherence tomography (OCT) is high-resolution technology detecting greater number dissections--particularly non-flow-limiting--compared to angiography. Their natural history and clinical implications remain unclear. The objectives the present study were assess morphology, healing response, outcomes OCT-detected using serial OCT imaging at baseline one year following drug-eluting (DES)...
<h3>Background</h3> The long-term results after second generation everolimus eluting bioresorbable vascular scaffold (Absorb BVS) placement in small vessels are unknown. Therefore, we investigated the impact of vessel size on outcomes, Absorb BVS implantation. <h3>Methods</h3> In ABSORB Cohort B Trial, out total study population (101 patients), 45 patients were assigned to undergo 6-month and 2-year angiographic follow-up (Cohort B1) 56 have at 1-year B2). pre-reference diameter (RVD) was...
ObjectivesThe purpose of this study was to assess the occurrence, predictors, and mechanisms optical coherence tomography (OCT)-detected coronary evaginations following drug-eluting stent (DES) implantation.
Background: Implantation of a metallic prosthesis creates local stiffness with subsequent mismatch in the compliance vessel wall, disturbances flow and heterogeneous distribution wall shear stress. Polymeric bioresorbable ABSORB scaffolds have less than platform stents. We sought to analyze vascular after implantation its long-term resolution bioresorption. Methods Results: A total 83 patients from trials underwent palpography investigations (30 53 Cohorts B, respectively) measure scaffolded...
Although 1-stent with provisional approach is the preferred strategy for treatment of bifurcation lesions, optimal according to lesion location still debatable. This study aimed identify whether clinical outcomes differed between left main (LM) and non-LM lesions in second-generation drug-eluting stent era. The Coronary Bifurcation Stenting registry III a retrospective multicenter 2648 patients who underwent percutaneous coronary intervention stent. Among population, 935 (35.3%) had an LM...
Two-dimensional (2D) frequency domain optical coherence tomography (FD-OCT) has enhanced our understanding of coronary atherosclerotic disease and is increasingly being used in conventional percutaneous intervention (PCI) to elucidate mechanisms improve complex anatomy. Since the first report three-dimensional (3D) OCT applied human vessels,1 technology rapidly progressed.2–10 Currently, main limitation this need for off-line creation 3D reconstructions—prototypes current generation ‘real...
High-intensity statin is strongly recommended in patients at very high risk (VHR) of atherosclerotic cardiovascular disease (ASCVD). However, concerns about statin-associated adverse effects result underuse this strategy practice.
This study, using a prospective cohort, evaluated the effectiveness and safety of off-label reduced-dose apixaban versus on-label dose in atrial fibrillation (AF) patients meeting single reduction criterion. The efficAcy Safety aPixaban In Real-world practice Korean frail with AF (ASPIRE) study is multicenter, observational cohort involving who met criterion apixaban. Patients were divided into two groups: standard (5 mg twice daily) reduced (2.5 daily). primary outcome was stroke/systemic...