A5107025578- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Lipoproteins and Cardiovascular Health
- Cardiovascular Function and Risk Factors
- Cerebrovascular and Carotid Artery Diseases
- Cardiac Valve Diseases and Treatments
- Heart Failure Treatment and Management
- Cardiac Health and Mental Health
- Peripheral Artery Disease Management
- Atrial Fibrillation Management and Outcomes
- Venous Thromboembolism Diagnosis and Management
- Cardiac Arrhythmias and Treatments
- Cardiac Structural Anomalies and Repair
- Coronary Artery Anomalies
- Cardiovascular Disease and Adiposity
- Aortic aneurysm repair treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrest and Resuscitation
- Cardiac, Anesthesia and Surgical Outcomes
- Heart Rate Variability and Autonomic Control
- Kawasaki Disease and Coronary Complications
- Cardiovascular Health and Disease Prevention
- Health Systems, Economic Evaluations, Quality of Life
Chonnam National University Hospital
2016-2025
Chonnam National University
2012-2024
Ministry of Health and Welfare
2014-2024
Chonnam National University Hwasun Hospital
2021-2024
Asan Medical Center
2023
Genomics (United Kingdom)
2023
Jangsung (South Korea)
2016-2023
Weatherford College
2021-2022
Illinois College
2022
Thrombolysis in Myocardial Infarction Study Group
2021
Endothelial progenitor cells (EPCs) are a promising cell source for the treatment of several ischemic diseases their potentials in neovascularization. However, application EPCs cell‐based therapy has shown low therapeutic efficacy due to hostile tissue conditions after ischemia. In this study, bio‐blood‐vessel (BBV) is developed, which produced using novel hybrid bioink (a mixture vascular‐tissue‐derived decellularized extracellular matrix (VdECM) and alginate) versatile 3D coaxial printing...
<h3>Importance</h3> Depression has been associated with poorer medical outcomes in acute coronary syndrome (ACS), but there are few data on the effects of antidepressant treatment long-term prognosis. <h3>Objective</h3> To investigate effect major adverse cardiac events (MACE) escitalopram depression patients recent ACS. <h3>Design, Setting, and Participants</h3> Randomized, double-blind, placebo-controlled trial conducted among 300 ACS enrolled from May 2007 to March 2013, follow-up...
Abstract Aims In patients with acute myocardial infarction (MI) and multivessel coronary artery disease, percutaneous intervention (PCI) of non-infarct-related reduces death or MI. However, whether selective PCI guided by fractional flow reserve (FFR) is superior to routine angiography alone unclear. The current trial sought compare FFR-guided angiography-guided for lesions among MI disease. Methods results Patients disease who had undergone successful the infarct-related were randomly...
Intravascular imaging-guided percutaneous coronary intervention (PCI) with intravascular ultrasound (IVUS) or optical coherence tomography (OCT) showed superior clinical outcomes compared angiography-guided PCI. However, the comparative effectiveness of OCT-guided and IVUS-guided PCI regarding is unknown.In this prospective, multicenter, open-label, pragmatic trial, we randomly assigned 2008 patients significant artery lesions undergoing in a 1:1 ratio to undergo either an The primary end...
Although venoarterial extracorporeal membrane oxygenation (VA-ECMO) is beneficial for the treatment of profound cardiogenic shock, peripheral VA-ECMO cannulation can increase left ventricular afterload, thus compromising myocardial recovery. We investigated whether early routine unloading reduce 30-day mortality compared with conventional approach in patients shock undergoing VA-ECMO.
Background The role of intravascular ultrasound (IVUS)-guided percutaneous coronary intervention (PCI) is still unclear in patients with acute myocardial infarction infarction. This study aimed to evaluate the long-term impact IVUS-guided PCI Methods and Results Among a total 13 104 infarction, enrolled Korea Acute Myocardial Infarction Registry-National Institutes Health, we selected who underwent second-generation drug-eluting stent implantation. primary outcome was risk target lesion...
There are limited randomized studies on patients undergoing multi-vessel percutaneous coronary intervention (PCI) comparing the outcomes between stent thickness and polymer types. To compare clinical of thick biodegradable polymer-based biolimus A9-eluting stents (BESs) thin durable zotarolimus-eluting (ZESs) in PCI. A total 936 who underwent artery stenting were randomly assigned to BES (n=472) or ZES (n=464) groups. The primary endpoint was 2-year major adverse cardiac events (MACEs), a...
Curcumin, a yellow pigment of turmeric in curry, is reported to interfere with nuclear factor (NF)-κB. This study was designed investigate the underlying pathway antiinflammation curcumin on endothelial cells. Human umbilical vein cells (HUVECs) were stimulated 10 ng/mL tumor necrosis (TNF)-α. Curcumin blocked activation NF-κB by TNF-α. also reduced intracellular reactive oxygen species (ROS), monocyte adhesion, phosphorylation c-Jun N-terminal kinase (JNK), p38, and signal transducer...
AimsWe used virtual histology-intravascular ultrasound (VH-IVUS) to evaluate the relation between coronary plaque characteristics and no-reflow in acute syndrome (ACS) patients.
Biodegradable polymers have been extensively used in biomedical applications, ranging from regenerative medicine to medical devices. However, the acidic byproducts resulting degradation can generate vigorous inflammatory reactions, often leading clinical failure. We present an approach prevent acid-induced responses associated with biodegradable polymers, here poly(lactide-co-glycolide), by using oligo(lactide)-grafted magnesium hydroxide (Mg(OH)2) nanoparticles, which neutralize...
Feasibility of coronary angiography (CAG) and percutaneous intervention (PCI) via left snuffbox approach is still concerned. We aimed to investigate efficacy safety the for CAG PCI.Left was tried in 150 patients who planned perform or PCI suspected myocardial ischemia between 1 November 2017 31 March 2018.Success rate radial artery (RA) cannulation 88.0% (n=132). Among 132 individuals, 58 (43.9%) acute syndrome (ACS) were included. The diameter RA significantly smaller than conventional...
Article Abstract Objective: Depression is common after acute coronary syndrome (ACS) and has adverse effects on prognosis. There are few evidence-based interventions for treating depression in ACS. This study investigated the efficacy safety of escitalopram depressive disorders identified 2-14 weeks a confirmed ACS episode. Method: A total 217 patients with DSM-IV (121 major 96 minor) were randomly assigned to receive flexible doses 5-20 mg/d (n = 108) or placebo 109) 24 weeks. The was...