A5048450239- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Acute Myocardial Infarction Research
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Peripheral Artery Disease Management
- Cerebrovascular and Carotid Artery Diseases
- Lipoproteins and Cardiovascular Health
- Vascular Procedures and Complications
- Dielectric properties of ceramics
- Coronary Artery Anomalies
- Cardiac tumors and thrombi
- Atrial Fibrillation Management and Outcomes
- Cardiovascular Syncope and Autonomic Disorders
- Ferroelectric and Piezoelectric Materials
- Heart Rate Variability and Autonomic Control
- Aortic aneurysm repair treatments
- Venous Thromboembolism Diagnosis and Management
- Pharmaceutical Economics and Policy
- Cardiovascular Disease and Adiposity
- Hormonal Regulation and Hypertension
- Cardiac electrophysiology and arrhythmias
- Microwave Dielectric Ceramics Synthesis
- Vascular anomalies and interventions
Seoul Medical Center
2024-2025
Inje University Ilsan Paik Hospital
2015-2024
Seoul St. Mary's Hospital
2015-2024
Catholic University of Korea
2016-2024
Severance Hospital
2023
Yonsei University
2023
Lodestar Research Corporation (United States)
2023
SMART Reading
2022
Singapore-MIT Alliance for Research and Technology
2022
Kangwon National University Hospital
2022
Background: Owing to the differential propensity for bleeding and ischemic events with response antiplatelet therapy, safety effectiveness of potent P2Y12 inhibitor ticagrelor in East Asian populations remain uncertain. Methods: In this multicenter trial, 800 Korean patients hospitalized acute coronary syndromes or without ST elevation intended invasive management were randomly assigned receive, a 1:1 ratio, (180 mg loading dose, 90 twice daily thereafter) clopidogrel (600 75 thereafter)....
In patients with coronary artery disease, some guidelines recommend initial statin treatment high-intensity statins to achieve at least a 50% reduction in low-density lipoprotein cholesterol (LDL-C). An alternative approach is begin moderate-intensity and titrate specific LDL-C goal. These alternatives have not been compared head-to-head clinical trial involving known disease.To assess whether treat-to-target strategy noninferior of for long-term outcomes disease.A randomized, multicenter,...
We sought to investigate the influence of target vessel on prognostic relevance fractional flow reserve (FFR) after percutaneous coronary intervention (PCI).A total 835 patients with available FFR second-generation drug-eluting stent (DES) implantation were included in this study. The primary outcome was target-vessel failure (TVF), including cardiac death, vessel-related myocardial infarction, and clinically driven revascularisation. left anterior descending artery (LAD) 603 (72.2%) non-LAD...
The anatomical criteria for the diagnosis of ischaemia referenced by fractional flow reserve (FFR) from non-invasive coronary computed tomographic angiography (CCTA), invasive (ICA), and intravascular ultrasound (IVUS) have not been evaluated contemporarily in a large-scale study. aim this study was to assess diagnostic value CCTA compared with ICA IVUS patients intermediate stenosis. CCTA, ICA, IVUS, FFR were performed 181 lesions severity. Minimal lumen diameter (MLD) per cent stenosis...
Procedural and clinical outcomes still remain unfavorable for patients with long coronary lesions who undergo stent-based interventions. Therefore, we compared the relative efficacy safety of resolute zotarolimus-eluting stents (R-ZES) sirolimus-eluting (SES) de novo lesions.This randomized, multicenter, prospective trial, called Percutaneous Treatment LONG Native Coronary Lesions With Drug-Eluting Stent-IV (LONG-DES IV) R-ZES SES in 500 (≥25 mm) native lesions. The primary end point trial...
Background We investigated the sex‐specific variations in distal radial access (DRA)–associated outcomes, as well factors influencing these by utilizing a comprehensive real‐world registry. Methods In this post‐hoc analysis of KODRA (Korean Prospective Registry for Evaluating Safety and Efficacy Distal Radial Approach) trial, we selected 4608 patients who underwent successful coronary procedures, including percutaneous intervention or angiography, via DRA. Primary end points were overall DRA...
Background: Whether prolonged dual antiplatelet therapy (DAPT) improves clinical outcomes after percutaneous coronary intervention for bifurcation lesion is uncertain. Methods and Results: We evaluated 2082 patients who were treated with drug-eluting stent lesions event free (no death, myocardial infarction [MI], cerebrovascular accident, thrombosis, or any revascularization) at 12 months the index procedure. Patients divided into 2 groups: DAPT ≥12-month group (n=1776) <12-month (n=306)....
De-escalation of dual-antiplatelet therapy through dose reduction prasugrel improved net adverse clinical events after acute coronary syndrome (ACS), mainly the bleeding without an increase in ischemic outcomes. However, whether such benefits are similarly observed those receiving complex procedures is unknown.To investigate de-escalation maintained percutaneous intervention (PCI) subgroup.This was a post hoc analysis HOST-REDUCE-POLYTECH-ACS trial, randomized, open-label,...
Procedural and clinical outcomes still remain unfavorable for patients with long coronary lesions who undergo percutaneous intervention. The current study, therefore, evaluated 2 innovative drug-eluting stents the management of long-lesion artery disease.This randomized, multicenter, prospective trial, called Long Drug-Eluting Stent (LONG-DES) V compared biodegradable polymer-based biolimus A9-eluting stent (BES) durable platinum chromium everolimus-eluting (PtCr-EES) in 500 (≥ 25 mm)...
Background and Objectives:We assessed plaque erosion of culprit lesions in patients with acute coronary syndrome real world practice.Subjects Methods: Culprit lesion rupture or was diagnosed optical coherence tomography (OCT).Intravascular ultrasound (IVUS) used to determine arterial remodeling.Positive remodeling defined as a index (lesion/ reference EEM [external elastic membrane area) >1.05.Results: A total 90 who had showing fibrous-cap discontinuity ruptured cavity were enrolled.36...
Differences between the recently suggested outcome-driven diagnostic threshold of home blood pressure (HBP) measurements and currently recommended HBP may cause a disagreement 24-hour ambulatory (ABP) in diagnosis hypertension. We evaluated agreement various thresholds (135/85, 130/85, 130/80 mm Hg) to ABP measurements, as reference method.Patients who were confirmed have high BP (≥140/90 at outpatient clinic referred. measurement was performed for 7 days triplicates every morning evening....
Many prognostic models have been developed to help physicians make medical decisions on treating patients with pulmonary embolism. Among these models, the Pulmonary Embolism Severity Index (PESI) has shown be a successful risk stratification tool for acute The PESI, however, had not applied embolism in Korea.The included this study were diagnosed by computed tomography at Inje University's Ilsan Paik Hospital between December 1999 and March 2007. Risk was performed using PESI. mortality rate...
The subsolidus phase relationship in the CaO – CuO TiO 2 ternary system at 950°C air was investigated. Total 26 samples having various nominal compositions were prepared by solid‐state reaction air, and their equilibrium phases analyzed powder X‐ray diffraction (XRD). CaCu 3 Ti 4 O 12 exhibits variable stoichiometry forms as Ca 1− x Cu 3+ ‐type (−0.019 ≤ ≤0.048) solid solution air. On basis of our results previous reports on binary diagrams, diagram could be constructed