Jan P. Stegemann

ORCID: 0000-0002-7989-7222
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About
Contact & Profiles
Research Areas
  • Electrospun Nanofibers in Biomedical Applications
  • Bone Tissue Engineering Materials
  • 3D Printing in Biomedical Research
  • Tissue Engineering and Regenerative Medicine
  • Periodontal Regeneration and Treatments
  • Collagen: Extraction and Characterization
  • Mesenchymal stem cell research
  • Osteoarthritis Treatment and Mechanisms
  • Cellular Mechanics and Interactions
  • Blood properties and coagulation
  • Pancreatic function and diabetes
  • Biomedical and Engineering Education
  • Tendon Structure and Treatment
  • Silk-based biomaterials and applications
  • Trauma, Hemostasis, Coagulopathy, Resuscitation
  • Hydrogels: synthesis, properties, applications
  • Heterotopic Ossification and Related Conditions
  • Bone and Dental Protein Studies
  • Ultrasound Imaging and Elastography
  • Bone fractures and treatments
  • Neuroscience and Neural Engineering
  • Cardiac Fibrosis and Remodeling
  • Angiogenesis and VEGF in Cancer
  • Ultrasound and Hyperthermia Applications
  • Hemostasis and retained surgical items

University of Michigan
2016-2025

University of Freiburg
2019-2020

University of Southern California
2020

Creative Commons
2017

Ann Arbor Center for Independent Living
2014-2015

Michigan United
2014

Rensselaer Polytechnic Institute
2004-2010

Georgia Institute of Technology
1998-2005

Harvard University
1997

Credo Reference (United States)
1997

Carbon nanotubes (CNT) are attractive for use in fiber-reinforced composite materials due to their very high aspect ratio, combined with outstanding mechanical and electrical properties. Composite comprising a collagen matrix embedded CNT were prepared by mixing solubilized Type I solutions of carboxylated single-walled carbon (SWNT) at concentrations 0, 0.2, 0.4, 0.8, 2.0 weight percent. Living smooth muscle cells incorporated the time gelation produce cell-seeded collagen-CNT matrices....

10.1002/jbm.a.30386 article EN Journal of Biomedical Materials Research Part A 2005-06-22

A main challenge in tissue engineering and regenerative medicine is achieving local efficient growth factor release to guide cell function. Gelatin a denatured form of collagen that cells can bind degrade through enzymatic action. In this study, gelatin microspheres were used bone morphogenetic protein 2 (BMP2). Spherical microparticles with diameters the range 2-6 µm created by an emulsification process stabilized crosslinking small molecule genipin. The degree was varied controlling...

10.1002/term.267 article EN Journal of Tissue Engineering and Regenerative Medicine 2010-05-21

Reliable control over the process of cell differentiation is a major challenge in moving stem cell-based therapies forward. The composition extracellular matrix (ECM) known to play an important role modulating differentiation. We have developed system encapsulate adult human mesenchymal cells (hMSC) within spherical three-dimensional (3D) microenvironments consisting defined mixture collagen Type I and agarose polymers. These protein-based beads were produced by emulsification liquid...

10.1002/bit.20614 article EN Biotechnology and Bioengineering 2005-01-01

Microencapsulation and delivery of stem cells in biomaterials is a promising approach to repairing damaged tissue minimally invasive manner. An appropriate biomaterial niche can protect the embedded from challenging environment host tissue, while also directing cell differentiation toward desired lineage. In this study, adult human mesenchymal (MSC) were hydrogel microbeads consisting chitosan type I collagen using an emulsification process. Glyoxal β-glycerophosphate used as chemical...

10.1159/000348359 article EN Cells Tissues Organs 2013-01-01
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