- Electrospun Nanofibers in Biomedical Applications
- Bone Tissue Engineering Materials
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Periodontal Regeneration and Treatments
- Collagen: Extraction and Characterization
- Mesenchymal stem cell research
- Osteoarthritis Treatment and Mechanisms
- Cellular Mechanics and Interactions
- Blood properties and coagulation
- Pancreatic function and diabetes
- Biomedical and Engineering Education
- Tendon Structure and Treatment
- Silk-based biomaterials and applications
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Hydrogels: synthesis, properties, applications
- Heterotopic Ossification and Related Conditions
- Bone and Dental Protein Studies
- Ultrasound Imaging and Elastography
- Bone fractures and treatments
- Neuroscience and Neural Engineering
- Cardiac Fibrosis and Remodeling
- Angiogenesis and VEGF in Cancer
- Ultrasound and Hyperthermia Applications
- Hemostasis and retained surgical items
University of Michigan
2016-2025
University of Freiburg
2019-2020
University of Southern California
2020
Creative Commons
2017
Ann Arbor Center for Independent Living
2014-2015
Michigan United
2014
Rensselaer Polytechnic Institute
2004-2010
Georgia Institute of Technology
1998-2005
Harvard University
1997
Credo Reference (United States)
1997
Carbon nanotubes (CNT) are attractive for use in fiber-reinforced composite materials due to their very high aspect ratio, combined with outstanding mechanical and electrical properties. Composite comprising a collagen matrix embedded CNT were prepared by mixing solubilized Type I solutions of carboxylated single-walled carbon (SWNT) at concentrations 0, 0.2, 0.4, 0.8, 2.0 weight percent. Living smooth muscle cells incorporated the time gelation produce cell-seeded collagen-CNT matrices....
A main challenge in tissue engineering and regenerative medicine is achieving local efficient growth factor release to guide cell function. Gelatin a denatured form of collagen that cells can bind degrade through enzymatic action. In this study, gelatin microspheres were used bone morphogenetic protein 2 (BMP2). Spherical microparticles with diameters the range 2-6 µm created by an emulsification process stabilized crosslinking small molecule genipin. The degree was varied controlling...
Reliable control over the process of cell differentiation is a major challenge in moving stem cell-based therapies forward. The composition extracellular matrix (ECM) known to play an important role modulating differentiation. We have developed system encapsulate adult human mesenchymal cells (hMSC) within spherical three-dimensional (3D) microenvironments consisting defined mixture collagen Type I and agarose polymers. These protein-based beads were produced by emulsification liquid...
Microencapsulation and delivery of stem cells in biomaterials is a promising approach to repairing damaged tissue minimally invasive manner. An appropriate biomaterial niche can protect the embedded from challenging environment host tissue, while also directing cell differentiation toward desired lineage. In this study, adult human mesenchymal (MSC) were hydrogel microbeads consisting chitosan type I collagen using an emulsification process. Glyoxal β-glycerophosphate used as chemical...