- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Function and Risk Factors
- Machine Learning in Healthcare
- Aortic aneurysm repair treatments
- Advanced MRI Techniques and Applications
- Lipoproteins and Cardiovascular Health
- Atrial Fibrillation Management and Outcomes
- Advanced X-ray and CT Imaging
- Cardiovascular Disease and Adiposity
- Cardiac and Coronary Surgery Techniques
- Vascular Procedures and Complications
- Venous Thromboembolism Diagnosis and Management
- Topic Modeling
- Infective Endocarditis Diagnosis and Management
- Aortic Thrombus and Embolism
- Health Systems, Economic Evaluations, Quality of Life
- Artificial Intelligence in Healthcare
- Blood Pressure and Hypertension Studies
Ulsan College
2016-2025
University of Ulsan
2016-2025
Asan Medical Center
2016-2025
Onze Lieve Vrouwziekenhuis Hospital
2018
Sungkyunkwan University
2018
Kangbuk Samsung Hospital
2018
Erasmus MC
2018
Institute of Cardiology
2018
Copenhagen University Hospital
2018
Rigshospitalet
2018
Percutaneous coronary intervention (PCI) is increasingly used to treat unprotected left main artery stenosis, although coronary-artery bypass grafting (CABG) has been considered be the treatment of choice.We randomly assigned patients with stenosis undergo CABG (300 patients) or PCI sirolimus-eluting stents patients). Using a wide margin for noninferiority, we compared groups respect primary composite end point major adverse cardiac cerebrovascular events (death from any cause, myocardial...
Although intravascular ultrasound (IVUS) guidance has been useful in stenting for unprotected left main coronary artery stenosis, its impact on long-term mortality is still unclear.In the MAIN-COMPARE registry, patients with stenosis a hemodynamically stable condition underwent elective under of IVUS (756 patients) or conventional angiography (219 patients). Patients acute myocardial infarction were excluded. The 3-year outcomes between 2 groups primarily compared using propensity-score...
Several studies have compared the treatment effects of coronary stenting and coronary-artery bypass grafting (CABG). However, there are limited data regarding long-term outcomes these two interventions for patients with unprotected left main artery disease.We evaluated 1102 disease who underwent stent implantation 1138 CABG in Korea between January 2000 June 2006. We adverse (death; a composite outcome death, Q-wave myocardial infarction, or stroke; target-vessel revascularization) use...
Most trials comparing percutaneous coronary intervention (PCI) with coronary-artery bypass grafting (CABG) have not made use of second-generation drug-eluting stents.We conducted a randomized noninferiority trial at 27 centers in East Asia. We planned to randomly assign 1776 patients multivessel artery disease PCI everolimus-eluting stents or CABG. The primary end point was composite death, myocardial infarction, target-vessel revascularization 2 years after randomization. Event rates during...
Background: Coronary computed tomographic angiography (CTA) is a reliable modality to detect coronary artery disease. However, CTA generally overestimates stenosis severity compared with invasive angiography, and angiographic does not necessarily imply hemodynamic relevance when fractional flow reserve (FFR) used as reference. CTA-based FFR (CT-FFR), using computational fluid dynamics (CFD), improves the correlation results but computationally demanding. More recently, new machine-learning...
We report findings from optical coherence tomography (OCT) of in-stent neoatherosclerosis as a cause drug-eluting stent (DES) failure.Optical and grayscale virtual histology intravascular ultrasound were performed in 50 patients (30 stable, 20 unstable angina) with DES restenosis lesions intimal hyperplasia >50% area. Median follow-up time was 32.2 months. Overall, 26 (52%) had at least 1 OCT-defined thin-cap fibroatheroma (TCFA)-containing neointima 29 (58%) neointimal rupture. Patients...
Late stent malapposition (LSM) after drug-eluting (DES) implantation has not been evaluated sufficiently in real-world practice.We the incidence, mechanisms, predictors, and long-term prognosis of LSM DES 557 patients (705 native lesions; sirolimus-eluting 538 lesions paclitaxel-eluting 167 lesions) whom intravascular ultrasound was performed at index 6-month follow-up. occurred 82 with 85 (12.1% overall, 95% CI 9.7% to 14.5%, 71 (13.2%) stents 14 [8.4%] stents, P=0.12]; incidence 25.0%...
Background: Procedural results for percutaneous coronary intervention (PCI) in vessels with chronic total occlusion (CTO) have improved recent years, and PCI strategies moved toward more complete revascularization liberal use of CTO-PCI. However, evidence evaluating CTO-PCI is limited to observational studies small clinical trials. Methods: In this open-label, multicenter, randomized, noninferiority trial, PCI-eligible patients were assigned receive either 1 2 strategies: or no the...
The risks and benefits of long-term dual antiplatelet therapy remain unclear.This prospective, multicenter, open-label, randomized comparison trial was conducted in 24 clinical centers Korea. In total, 5045 patients who received drug-eluting stents were free major adverse cardiovascular events bleeding for at least 12 months after stent placement enrolled between July 2007 2011. Patients to receive aspirin alone (n=2514) or clopidogrel plus (n=2531). primary end point a composite death...
Background— We assessed the optimal intravascular ultrasound (IVUS) stent area to predict angiographic in-stent restenosis (ISR) after sirolimus-eluting implantation for unprotected left main coronary artery (LM) disease. Methods and Results— A total of 403 patients treated with single- or 2-stent strategies (crushing T-stent) had immediate poststenting IVUS 9-month follow-up angiography. Poststenting minimal (MSA) was measured in each 4 segments: ostial anterior descending (LAD), circumflex...
In this paper, we propose an effective electrocardiogram (ECG) arrhythmia classification method using a deep two-dimensional convolutional neural network (CNN) which recently shows outstanding performance in the field of pattern recognition. Every ECG beat was transformed into grayscale image as input data for CNN classifier. Optimization proposed classifier includes various learning techniques such batch normalization, augmentation, Xavier initialization, and dropout. addition, compared our...
Long-term comparative outcomes after percutaneous coronary intervention (PCI) with drug-eluting stents and coronary-artery bypass grafting (CABG) for left main artery disease are highly debated.In the PRECOMBAT trial (Premier of Randomized Comparison Bypass Surgery versus Angioplasty Using Sirolimus-Eluting Stent in Patients Left Main Coronary Artery Disease), patients unprotected were randomly assigned to undergo PCI sirolimus-eluting (n=300) or CABG 13 hospitals Korea from April 2004...
Recently a number of studies demonstrated impressive performance on diverse vision-language multi-modal tasks such as image captioning and visual question answering by extending the BERT architecture with pre-training objectives. In this work we explore broad set representation learning in medical domain, specifically using radiology images unstructured report. We propose Medical Vision Language Learner (MedViLL), which adopts BERT-based combined novel attention masking scheme to maximize...
We evaluated the incidence and predictors of single multiple plaque ruptures in acute myocardial infarction (AMI) stable angina pectoris (SAP).We performed 3-vessel intravascular ultrasound (IVUS) examination 235 patients: 122 had AMI, 113 SAP. Plaque rupture infarct-related or target lesions occurred 80 AMI patients (66%) 31 SAP (27%) (P<0.001). Non-infarct-related non-target artery 21 (17%) 6 (5%) (P=0.008). Multiple were observed 24 (20%) 7 (6%) (P=0.004). Therefore, at least 1 any...