- Cardiac Valve Diseases and Treatments
- Aortic Disease and Treatment Approaches
- Infective Endocarditis Diagnosis and Management
- Cardiac Structural Anomalies and Repair
- Atrial Fibrillation Management and Outcomes
- Aortic aneurysm repair treatments
- Cardiac Imaging and Diagnostics
- Cardiac and Coronary Surgery Techniques
- Mechanical Circulatory Support Devices
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiovascular Function and Risk Factors
- Coronary Interventions and Diagnostics
- Cardiac pacing and defibrillation studies
- Congenital Heart Disease Studies
- Transplantation: Methods and Outcomes
- Cardiac Arrest and Resuscitation
- Infectious Aortic and Vascular Conditions
- Cardiac tumors and thrombi
- Pericarditis and Cardiac Tamponade
- Antiplatelet Therapy and Cardiovascular Diseases
- Heart Failure Treatment and Management
- Renal Transplantation Outcomes and Treatments
- Trauma Management and Diagnosis
- Reconstructive Surgery and Microvascular Techniques
Seoul National University
2025
Asan Medical Center
2015-2024
Ulsan College
2015-2024
University of Ulsan
2015-2024
Eulji University
2018
Second Military Medical University
2017
Changhai Hospital
2017
Thoracic Surgery Foundation
2016
Landscape Research Group
2016
National Heart Institute
2015
The timing and indications for surgical intervention to prevent systemic embolism in infective endocarditis remain controversial. We conducted a trial compare clinical outcomes of early surgery conventional treatment patients with endocarditis.
Most trials comparing percutaneous coronary intervention (PCI) with coronary-artery bypass grafting (CABG) have not made use of second-generation drug-eluting stents.We conducted a randomized noninferiority trial at 27 centers in East Asia. We planned to randomly assign 1776 patients multivessel artery disease PCI everolimus-eluting stents or CABG. The primary end point was composite death, myocardial infarction, target-vessel revascularization 2 years after randomization. Event rates during...
The optimal timing of surgical intervention remains controversial in asymptomatic patients with very severe aortic stenosis. We therefore compared the long-term results early surgery and a conventional treatment strategy.From 1996 to 2006, we prospectively included total 197 consecutive (99 men; age, 63+/-12 years) Patients were excluded if they had angina, syncope, exertional dyspnea, ejection fraction <0.50, significant mitral valve disease, or age >85 years. Very stenosis was defined as...
The proper treatment option for patients with type A intramural hematoma (IMH), a variant form of classic aortic dissection (AD), remains controversial. We assessed the outcome our institutional policy urgent surgery unstable and initial medical stable in cases complications.Among 357 consecutive acute syndrome, 101 (28.3%) had IMH 256 AD. Urgent operations were performed 224 AD (87.5%) 16 (15.8%; P<0.001). remaining 85 received treatment, adverse clinical events developed 31 (36.5%) within...
Objective: In acute DeBakey type I aortic dissection, it is still controversial whether to perform extended replacement improve long-term outcome or use a conservative strategy with ascending and hemiarch palliate life-threatening condition. Methods: Between 1999 2009, 188 consecutive patients (93 women; mean age, 57.4 ± 11.7 years) dissection underwent (Hemiarch group; n = 144) total arch (Total 44) in conjunction aorta replacement. Clinical outcomes were compared after adjustment for...
<h3>Background:</h3> Persistent significant tricuspid regurgitation (TR) after successful left-sided valve surgery is frequently reported. <h3>Objectives:</h3> To evaluate the incidence, risk factors and clinical impact of development late TR surgery. <h3>Methods results:</h3> 638 patients (356 men, mean age 52 (SD 14) years) who had mild (⩽grade 2/4) underwent without any procedure for were analysed. Development was defined as a increase by more than one grade final ⩾3/4 at follow-up...
Background— Although previous studies have compared the treatment effects of percutaneous coronary intervention and artery bypass grafting (CABG), long-term outcomes beyond 1 year among patients with multivessel disease who underwent drug-eluting stents (DES) or CABG not been evaluated. Methods Results— Between January 2003 December 2005, 3042 implantation DES (n=1547) (n=1495). The primary end point was all-cause mortality. In a crude analysis, rate mortality significantly higher in than...
The decision to repair mild-to-moderate functional tricuspid regurgitation (TR) during left-side heart surgery remains controversial. Objectives To avoid heterogeneity in patient population, patients with TR undergoing isolated mechanical mitral valve (MV) replacement for rheumatic diseases were evaluated.Between 1997 and 2009, 236 underwent first-time MV (n=123; group) or without (n=113; non-repair (TV) repair. Survival, valve-related complications, TV function these two groups compared...
We aimed to compare imaging findings of infective endocarditis between computed tomography (CT) and transoesophageal echocardiography (TEE) using surgical inspection as a reference standard. Forty-nine patients (aged 54 ± 17 years, 69% men) who underwent pre-operative CT TEE for were included. Twelve these had prosthetic valve endocarditis. Imaging classified vegetation, leaflet perforation, abscess/pseudoaneurysm, paravalvular leakage. Diagnostic performances evaluated Interobserver...
Although mitral valve (MV) repair is known to be superior replacement in overall clinical outcomes, the appropriateness of for rheumatic MV disease remains controversial because risks recurrent dysfunction and need re-operation.From 1997 2007, 540 patients underwent either isolated (n=122) or with a mechanical prosthesis (n=418) treatment disease. Survival morbidity were evaluated using Kaplan-Meier analysis Cox regression, including propensity score analysis.Follow-up was complete 96.1%...
Intra-aortic balloon counterpulsation (IABP) during extracorporeal life support (ECLS) for cardiogenic shock may improve pulsatility and coronary perfusion, thereby promoting recovery of cardiac function. However, the risks benefits IABP ECLS in real clinical settings have not been evaluated. This study aims to evaluate effect on early outcome shock.We evaluated 253 adult patients (aged 58.8 ± 15.3 [mean standard deviation] years, 154 males) undergoing from January 2005 August 2012. Of them,...
Objective Unlike degenerative mitral valve (MV) disease, the advantages of repair procedure over replacement have been debated in rheumatic MV disease. This study aims to evaluate impact procedural types on long-term outcomes through analyses a large data set from an endemic area Methods We evaluated 1731 consecutive patients (52.3±12.5 years; 1190 women) undergoing surgery for disease between 1997 and 2015. Long-term survival valve-related were compared procedures. To adjust selection bias,...
Background— The long-term benefits of the maze procedure in patients with chronic atrial fibrillation undergoing mechanical valve replacement who already require lifelong anticoagulation remain unclear. Methods and Results— We evaluated adverse outcomes (death; thromboembolic events; composite death, heart failure, or valve-related complications) 569 fibrillation–associated valvular disease underwent (n=317) without (n=252) a concomitant between 1999 2010. After adjustment for differences...
<h3>Background</h3> Although recent studies contributed to an improved understanding of the prognosis patients undergoing tricuspid valve (TV) surgery, data are limited certain causes regurgitation (TR) or types surgery. <h3>Objective</h3> This study aimed identify predictors clinical outcomes TV surgery for severe TR various aetiologies. <h3>Design</h3> A retrospective cohort study. <h3>Setting</h3> single tertiary referral centre. <h3>Patients</h3> 449 consecutive (152 men, aged 56.2±12. 3...
Optimal management strategy of acute aortic dissection (AD) with retrograde extension from entry tear in the descending aorta into ascending remains undetermined.Of 538 patients who were diagnosed as having AD 1999 through 2011, 49 (37 men; 52.5±13.1 years) identified aorta. Sixteen clinically stable thrombosed false lumen treated medically (MED group), whereas 33 underwent replacement (SURG group) on an intention-to-treat basis. In MED group, 1 patient was converted to urgent surgery and 2...