Kyusup Lee

ORCID: 0000-0003-0149-5503
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About
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Research Areas
  • Coronary Interventions and Diagnostics
  • Cardiac Imaging and Diagnostics
  • Cardiac Valve Diseases and Treatments
  • Acute Myocardial Infarction Research
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Peripheral Artery Disease Management
  • Cardiovascular Function and Risk Factors
  • Cardiac, Anesthesia and Surgical Outcomes
  • Lipoproteins and Cardiovascular Health
  • Cardiovascular Disease and Adiposity
  • Atrial Fibrillation Management and Outcomes
  • Endometriosis Research and Treatment
  • Health Systems, Economic Evaluations, Quality of Life
  • Heart Failure Treatment and Management
  • Cerebrovascular and Carotid Artery Diseases
  • Uterine Myomas and Treatments
  • Aortic Disease and Treatment Approaches
  • Venous Thromboembolism Diagnosis and Management
  • Systemic Sclerosis and Related Diseases
  • Endometrial and Cervical Cancer Treatments
  • Pharmaceutical Economics and Policy
  • Reproductive System and Pregnancy
  • Infective Endocarditis Diagnosis and Management
  • Nutrition, Health and Food Behavior
  • Heart Rate Variability and Autonomic Control

Catholic University of Korea
2019-2025

Daejeon St. Mary's Hospital
2019-2025

Seoul St. Mary's Hospital
2020-2023

Asan Medical Center
2017-2020

Ulsan College
2017-2020

University of Ulsan
2017-2020

Pusan National University Hospital
2012-2019

Pusan National University
2005-2013

Percutaneous coronary intervention (PCI) for bifurcation lesions presents several difficulties and often results in suboptimal procedural, postprocedural clinical outcomes. While the provisional 1-stent strategy is generally favored its simplicity favorable outcomes, a few studies suggest no significant difference between 2-stent techniques true lesions. Drug-eluting balloons (DEBs) have demonstrated potential small vessel disease, including side branches. However, compared with plus DEB...

10.1016/j.amjcard.2025.01.025 article EN cc-by-nc-nd The American Journal of Cardiology 2025-01-29

Background: The increasing prevalence of severe calcified coronary artery disease has expanded the role rotational atherectomy (RA) in percutaneous intervention (PCI). In drug-eluting stent (DES) era, RA remains a key tool for complex lesion modification. This review focuses on its clinical outcomes and evolving indications. Methods: was conducted as narrative review, focusing most relevant studies regarding DES era. Articles were identified through systematic PubMed search. Results:...

10.3390/jcm14072199 article EN Journal of Clinical Medicine 2025-03-24

An increase in the level of vascular endothelial growth factor (VEGF) production has been reported peritoneal fluid (PF) endometriosis patients. This suggests that changes permeability and angiogenesis play an important role pathophysiology this disease. study examined effects PF obtained from patients on release VEGF by neutrophils monocytes.Neutrophils monocytes were young healthy volunteers cultured with either (EPF) (n=18) or a control group (CPF) (n=4). A human monocyte/macrophage cell...

10.1093/humrep/del077 article EN Human Reproduction 2006-03-20

Background Data are still limited regarding whether there differential long-term outcomes after percutaneous coronary intervention versus artery bypass grafting (CABG) for left main disease with or without diabetes mellitus (DM). Methods and Results Using the 10-year data from MAIN-COMPARE (Revascularization Unprotected Left Main Coronary Artery Stenosis: Comparison of Percutaneous Angioplasty Versus Surgical Revascularization) registry, we sought to examine effect DM on comparative CABG in...

10.1161/jaha.119.015372 article EN cc-by-nc-nd Journal of the American Heart Association 2020-04-20

Background The secondary prevention with pharmacologic therapy is essential for preventing recurrent cardiovascular events in patients experiencing acute myocardial infarction. Guideline-based optimal medical (OMT) infarction consists of antiplatelet therapy, angiotensin-converting enzyme inhibitors/angiotensin II receptor blockers, β-blockers, and statins. We aimed to determine the prescription rate OMT use at discharge evaluate impact on long-term clinical outcomes who underwent...

10.1161/jaha.121.024370 article EN cc-by-nc-nd Journal of the American Heart Association 2023-05-09

Endometriosis is a gynecological disease defined as the presence of endometrial tissue outside uterine cavity, which caused by various factors. Proteomic analysis two sets eutopic cells collected from menstrual blood females with (n=6; n=3) or without endometriosis was performed to identify novel potential biomarkers for endometriosis. The data revealed that samples patients had stem cell characteristics, they higher mRNA expression levels octamer-binding transcription factor 4 (Oct-4),...

10.3892/mmr.2013.1469 article EN Molecular Medicine Reports 2013-05-10

Background and Objectives: Data is still limited regarding clinical outcomes of rotational atherectomy (RA) after percutaneous coronary intervention. We sought to evaluate RA. Materials Methods: This multi-center registry enrolled patients who underwent RA during PCI from nine tertiary centers in Korea between January 2010 October 2019. The primary endpoint was target-vessel failure (TVF; the composite outcome cardiac death, spontaneous myocardial infarction, or revascularization). Results:...

10.3390/medicina57070694 article EN cc-by Medicina 2021-07-07

Abstract Body mass index (BMI), as an important risk factor related to metabolic disease. However, in some studies higher BMI was emphasized a beneficial the clinical course of patients after acute myocardial infarction (AMI) concept known “BMI paradox.” The purpose this study investigate how outcomes treated for AMI differed according levels. A total 10,566 Korea Acute Myocardial Infarction Registry-National Institutes Health (KAMIR-NIH) from May 2010 June 2015 were divided into three...

10.1038/s41598-023-43493-0 article EN cc-by Scientific Reports 2024-03-01

Objectives: The purpose of this study was to identify clinical risk factors for the recurrence ovarian endometrioma after cystectomy in Korean women with long-term postoperative medical therapy. Material and Methods: A total 134 patients who were surgically treated endometriotic cysts at Pusan National University Hospital included retrospective study. All received treatment least 12 months first-line conservative surgery. Several epidemiologic variables analyzed as possible recurrence....

10.5603/gp.a2018.0105 article EN cc-by-nc-nd Ginekologia Polska 2018-11-30

Abstract Statin therapy is essential for secondary prevention in patients with atherosclerotic cardiovascular disease (ASCVD). However, the effects of statin receiving chronic dialysis remain uncertain. We aimed to evaluate effect on long-term mortality after a first-time ASCVD. Patients maintenance aged ≥ 18 years ASCVD event between 2013 and 2018 were included Korean National Health Insurance Service database. Associations use examined using Cox proportional hazards regression models...

10.1038/s41598-023-37819-1 article EN cc-by Scientific Reports 2023-07-06

Background and Purpose In young patients (aged 18–60 years) with patent foramen ovale (PFO)-associated stroke, percutaneous closure has been found to be useful for preventing recurrent ischemic stroke or transient attack (TIA). However, it remains unknown whether PFO is also beneficial in older patients.Methods Patients aged ≥60 years who had a cryptogenic from ten hospitals South Korea were included. The effect of plus medical therapy over alone was assessed by propensity-score matching...

10.5853/jos.2023.03265 article EN cc-by-nc Journal of Stroke 2024-05-31

There are numerous but conflicting data regarding gender differences in outcomes following percutaneous coronary intervention (PCI). Furthermore, clinical with acute myocardial infarction (AMI) PCI Asian population remain uncertain because of the under-representation previous trials.

10.11909/j.issn.1671-5411.2020.11.006 article EN PubMed 2020-11-28

Abstract Background Little is known about how the relative treatment effect of percutaneous coronary intervention (PCI) and coronary‐artery bypass grafting (CABG) on clinical outcomes in ostial or shaft left main artery (LMCA) disease has evolved over time. Methods This study included 2,112 patients with LMCA from IRIS‐MAIN registry who underwent PCI ( n = 1,329) CABG 783). Patients were stratified by time period based stent type availability: wave 1 (1995–2002, bare‐metal [BMS] era); 2...

10.1002/ccd.28119 article EN Catheterization and Cardiovascular Interventions 2019-02-05

Purpose The three‐dimensional (3D) principal strain represents the major direction and magnitude of deformation by its definition can be measured using 3D echocardiography. We aimed to validate echocardiographic left ventricular ( LV ) global strains as an assessment contractility comparison with gold standard invasive measurements. Methods In 14 beagles, pressure–volume loop was recorded invasively measure end‐systolic relationship ESPVR dP /dt reference indicators representing...

10.1002/mp.13509 article EN Medical Physics 2019-03-26
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