- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Valve Diseases and Treatments
- Hemodynamic Monitoring and Therapy
- Acute Kidney Injury Research
- Anesthesia and Sedative Agents
- Cardiovascular Function and Risk Factors
- Cardiac and Coronary Surgery Techniques
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Transplantation: Methods and Outcomes
- Cardiac Imaging and Diagnostics
- Cardiac Arrest and Resuscitation
- Anesthesia and Pain Management
- Respiratory Support and Mechanisms
- Thermal Regulation in Medicine
- Hip and Femur Fractures
- Blood transfusion and management
- Esophageal Cancer Research and Treatment
- Anesthesia and Neurotoxicity Research
- Aortic Disease and Treatment Approaches
- Nausea and vomiting management
- Intensive Care Unit Cognitive Disorders
- Mechanical Circulatory Support Devices
- Cardiac Structural Anomalies and Repair
- Nutrition and Health in Aging
- Frailty in Older Adults
Asan Medical Center
2016-2025
Ulsan College
2016-2025
University of Ulsan
2016-2025
Genetic Analysis (Norway)
2016
Korea University
2005
University of Pennsylvania
2000
Seoul National University
2000
Hypoalbuminemia may increase the risk of acute kidney injury (AKI). The authors investigated whether immediate preoperative administration 20% albumin solution affects incidence AKI after off-pump coronary artery bypass surgery.In this prospective, single-center, randomized, parallel-arm double-blind trial, 220 patients with serum levels less than 4.0 g/dl were administered 100, 200, or 300 ml human according to level (3.5 3.9, 3.0 3.4, g/dl, respectively) an equal volume saline before...
Abstract Given that surgical stress response and excision may increase the likelihood of post-surgery cancer dissemination metastasis, appropriate choice anesthetics be important for oncologic outcomes. We evaluated association used general anesthesia with overall survival recurrence-free in patients who underwent esophageal surgery. Adult (922) elective surgery were included. The divided into two groups according to administered during surgery: volatile (VA) or intravenous propofol (TIVA)....
The aim of this study was to evaluate whether remote ischaemic preconditioning (RIPC) combined with postconditioning (RIPostC) improves the clinical outcomes patients undergoing cardiac surgery. From June 2009 November 2010, 1280 who underwent elective surgery were randomized into RIPC RIPostC group or control in morning In group, four cycles 5-min ischaemia and reperfusion administered twice upper limb—before cardiopulmonary bypass (CPB) coronary anastomoses for after CPB RIPostC. primary...
Airway driving pressure, easily measured as plateau pressure minus PEEP, is a surrogate for alveolar stress and strain. However, the effect of its targeted reduction remains unclear.In this multicentre trial, patients undergoing lung resection surgery were randomised to either group (n=650) receiving an recruitment/individualised PEEP deliver lowest or conventional protective ventilation with fixed 5 cm H2O. The primary outcome was composite pulmonary complications within 7 days...
Transit-time flow measurement (TTFM) is frequently used to evaluate intraoperative quality control during coronary artery bypass grafting (CABG) and has the ability assess graft failure intraoperatively. However, perioperative factors affecting TTFM CABG remain poorly understood. Patients who underwent at a single institution between July 2016 May 2018 were prospectively evaluated. blood viscosity measured haemodynamically, while mean (mL/min), pulsatility index, diastolic filling recorded....
Background: Minimalist transcatheter aortic valve replacement (TAVR) under monitored anesthesia care (MAC) emphasizes early recovery. Remimazolam is a novel benzodiazepine with short recovery time. This study hypothesized that remimazolam non-inferior to dexmedetomidine in terms of after TAVR.Methods: In this retrospective observational study, was compared patients who underwent TAVR MAC at tertiary academic hospital between July 2020 and 2022. The primary outcome timely TAVR, defined as...
Current guidelines recommend the perioperative continuation of aspirin in patients with coronary drug-eluting stents (DES) undergoing noncardiac surgery. However, supporting evidence is limited.
Background: To compare tracheal temperature (TET) with nasopharyngeal (TNP) in patients undergoing cardiac surgery using cardiopulmonary bypass (CPB). Methods: TET was measured a thermistor the cuff of an endotracheal tube and TNP monitored esophageal stethoscope. Depending on management CPB strategy, operation divided into four periods (pre-CPB, cooling, rewarming, post-CPB). A Bland–Altman analysis carried out to each period. The concordance correlation coefficient for repeated measures...
Background Newly developed atrial fibrillation (AF) in patients who have undergone an esophagectomy increases the incidence of postoperative complications. However, clinical implications AF not been fully elucidated these patients. This retrospective observational study investigated predictors for and effect on mortality esophageal cancer undergoing esophagectomy. Methods evaluated 583 esophagectomy, from January 2005 to April 2012. was defined as newly requiring treatment. The risk factors...
BACKGROUND: Remimazolam is a recently marketed ultrashort-acting benzodiazepine. This drug considered safe and effective during general anesthesia; however, limited information available about its effects on patients undergoing cardiac surgery. Therefore, the present study was conducted to evaluate efficacy hemodynamic stability of bolus administration remimazolam anesthesia induction in METHODS: Patients elective surgery were randomly assigned any 1 following 3 groups: with continuous...
Abstract Background Cardiopulmonary resuscitation (CPR) is the cornerstone intervention for cardiac arrest, with extracorporeal CPR (ECPR) demonstrating enhanced survival and neurologic outcomes in in‐hospital arrest. This study explores time interval between initiation onset of membrane oxygenation (ECMO) ECPR recipients, investigating its impact on outcomes. Methods retrospective analysis included 1950 adults who received at a single medical center March 2019 April 2023. Data from 198...
Abstract Introduction Saline-based and hydroxyethyl starch solutions are associated with increased risk of renal dysfunction. In the present study, we tested hypothesis that balanced a limited volume solution (renal protective fluid management [RPF] strategy) would decrease incidence postoperative acute kidney injury (AKI) improve clinical outcomes in patients undergoing off-pump coronary artery bypass graft surgery (OPCAB). Methods We investigated 783 who underwent elective OPCAB. All OPCAB...
The aim of this study was to evaluate the efficacy ondansetron and ramosetron in reduction post-operative nausea vomiting (PONV) associated with patient-controlled analgesia (PCA) after cardiac surgery.A total 320 patients scheduled for elective surgery were enrolled. Patients randomly assigned one four treatment regimens (n=80 each group): no prophylactic antiemetics (group P); intravenous (i.v.) 4 mg at end 12 added PCA O); i.v. 0.3 R1); 0.6 R2).The incidence PONV during 48-h period lower...
The ratio of early transmitral flow velocity to diastolic the mitral annulus (E/e') correlates with left ventricular (LV) filling pressure. In particular, an E/e' more than 15 is excellent predictor increased LV authors evaluated prognostic implications preoperative estimated pressure, assessed by ratio, in patients undergoing off-pump coronary artery bypass graft surgery.This observational study investigated 1,048 consecutive adults elective surgery. primary outcome was occurrence major...
Background/Aims Infections are major causes of both early and late death after lung transplantation (LT). The development prophylaxis strategies has altered the epidemiology post-LT infections; however, recent epidemiological data limited. We evaluated infections LT at our institution by time occurrence, site infections, microbiologic etiologies. Methods All consecutive patients undergoing or heart-lung between October 2008 August 2014 were enrolled. Cases initially identified from...
In Brief Background Lung transplantation (LTPL) is considered as a salvage therapeutic option in patients with end-stage lung disease. However, there lack of sufficient data on the use LTPL acute respiratory distress syndrome (ARDS). Although are few case reports transplant for ARDS, no series exists up to date. The aim this study was evaluate clinical outcomes ARDS accordance status. Methods Patients who had severe (PaO2/FiO2 ratio ≤ 100 mm Hg positive end-expiratory pressure ≥ 5 cm H2O)...
Objective The efficacy and side-effects of nefopam were prospectively compared with those fentanyl for patient-controlled analgesia (PCA) following cardiac surgery. Methods Patients scheduled to undergo surgery randomly assigned between three PCA groups (nefopam, or + fentanyl). Pain was assessed at rest during movement 12, 24, 36, 48 72 h after using a visual analogue scale (VAS). Total infused volume, number rescue drug injections, duration intubation length stay in the intensive care unit...
This study aimed to compare the controlling nutritional status (CONUT) score, prognostic index (PNI), and geriatric risk (GNRI) for predicting postoperative outcomes in patients with esophageal squamous cell carcinoma undergoing esophagectomy. We retrospectively reviewed data of 1265 consecutive who underwent elective surgery. The were classified into no risk, low-risk, moderate-risk, high-risk groups based on scores. moderate-risk (hazard ratio [HR]: 1.55, 95% confidence interval [CI]:...
Several studies have shown in animal models that remote ischemic preconditioning (rIPC) has a neuroprotective effect. However, randomized controlled trial human subjects to investigate the effect of rIPC after cardiac surgery not yet been reported. Therefore, we performed this pilot study determine whether reduced occurrence postoperative cognitive dysfunction patients who underwent off-pump coronary artery bypass graft (OPCAB) surgery.Seventy OPCAB were assigned either control or group...