A5021717946- Tuberculosis Research and Epidemiology
- Mycobacterium research and diagnosis
- Infectious Diseases and Tuberculosis
- Pneumocystis jirovecii pneumonia detection and treatment
- Infectious Diseases and Mycology
- Transplantation: Methods and Outcomes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Pneumonia and Respiratory Infections
- Diagnosis and treatment of tuberculosis
- Tracheal and airway disorders
- Quinazolinone synthesis and applications
- Polyomavirus and related diseases
- Cerebrovascular and Carotid Artery Diseases
- Renal Transplantation Outcomes and Treatments
- Respiratory Support and Mechanisms
- Intracranial Aneurysms: Treatment and Complications
- Antibiotic Resistance in Bacteria
- Organ Transplantation Techniques and Outcomes
- Cytomegalovirus and herpesvirus research
- Mechanical Circulatory Support Devices
- Moyamoya disease diagnosis and treatment
- Atrial Fibrillation Management and Outcomes
- Rheumatoid Arthritis Research and Therapies
- Cancer therapeutics and mechanisms
- Restless Legs Syndrome Research
Ulsan College
2015-2024
University of Ulsan
2015-2024
Asan Medical Center
2015-2024
Chung-Ang University Hospital
2022
Gangneung Asan Hospital
2005-2017
In-Q-Tel
2015
Research Institute of Radiology
2015
Creative Commons
2015
Christie's
2015
Fundación Juan March
2015
Little is known about the long-term natural history of Mycobacterium avium complex lung disease (MAC-LD) in untreated patients with stable course.The aim this study was to investigate course MAC-LD, a focus on factors associated clinical deterioration, spontaneous sputum conversion and prognosis.Of 488 diagnosed MAC-LD between 1998 2011, 305 (62.5%) showed progressive resulting treatment initiation within 3 years diagnosis 115 (23.6%) exhibited for at least median follow-up duration 5.6...
This study analyzed the recurrence rate and risk factors for of Mycobacterium avium complex (MAC) lung disease in patients successfully treated this disease. The medical records 158 MAC at a tertiary referral center South Korea between March 2000 December 2009 were retrospectively analyzed. Recurrence was recorded, associated with mean age 60.7 ± 11.1 years. etiologic agent 77 (48.7%) intracellulare 81 (51.3%). Radiographic features included nodular bronchiectatic 95 (60.1%), fibrocavitary...
<b><i>Background:</i></b> Few studies have investigated the impact of diabetes mellitus (DM), a globally increasing metabolic disease, on treatment outcomes and long-term survival in patients with multidrug-resistant forms tuberculosis (MDR-TB). <b><i>Objectives:</i></b> We analyzed large cohort to assess DM MDR-TB. <b><i>Methods:</i></b> MDR-TB newly diagnosed or retreated between 2000 2002 followed for 8-11 years were...
Nontuberculous mycobacterial (NTM) disease and tuberculosis (TB) develop during anti-tumour necrosis factor (TNF)-α therapy. We compared clinical characteristics outcomes between the two diseases. A total of 1165 patients were screened for TB treated with TNF-α antagonists from July 2004 to 2013 following conditions: inflammatory bowel (n = 422), rheumatoid arthritis 320), ankylosing spondylitis 389). NTM diagnosed at baseline screening in four three patients, respectively, developed...
We investigated the prevalence of latent tuberculosis infection (LTBI) among health care workers (HCWs) and analyzed its risk factors in South Korea.A standard questionnaire regarding baseline demographics for LTBI was given to each participant tuberculin skin test (TST), QuantiFERON-TB GOLD In-Tube (QFT-GIT) assay, chest radiography were performed.A total 493 participants, 152 (30.8%) doctors 341 (69.2%) nurses enrolled eight tertiary referral hospitals. The mean age subjects 30.6 years...
The present study investigated the risk of active tuberculosis in patients with inflammatory bowel disease (IBD) treated vedolizumab or ustekinumab, actual clinical settings a country an intermediate burden. medical records 238 IBD who received ustekinumab were retrospectively reviewed at tertiary referral center South Korea. All had ≥ 3 months follow-up duration and underwent latent infection screening test before initiation administration these drugs. Of enrolled, 181 Crohn's disease, 57...
Background/Aims Infections are major causes of both early and late death after lung transplantation (LT). The development prophylaxis strategies has altered the epidemiology post-LT infections; however, recent epidemiological data limited. We evaluated infections LT at our institution by time occurrence, site infections, microbiologic etiologies. Methods All consecutive patients undergoing or heart-lung between October 2008 August 2014 were enrolled. Cases initially identified from...
Abstract Background Improving health-related quality of life (HRQOL) has emerged as a priority in the management nontuberculous mycobacterial pulmonary disease (NTM-PD). We aimed to evaluate HRQOL and its changes after 6 months’ treatment patients with NTM-PD. Methods The NTM-KOREA is nationwide prospective cohort enrolling initiating for NTM-PD 8 institutions across South Korea. conducted Quality Life–Bronchiectasis (QOL-B) at 6-month intervals evaluated baseline scores (higher indicate...
The isolation of non-tuberculous mycobacteria (NTM) has been increasing in South Korea. To date, however, the cause this increase not determined, and it remains unclear whether use liquid media contributed to increase. aim study was evaluate factors associated with NTM impact on culture.Mycobacterial smear/culture results respiratory specimens (sputum bronchial aspirates), obtained during years 2002, 2005, 2010, were retrieved analyzed retrospectively.During 83,096 sputum collected from...
Reactivation of latent tuberculosis infection (LTBI) is an important complication in patients treated with tumor necrosis factor-alpha (TNF-α) blocking agents. However, the best method for LTBI detection before initiation anti-TNF therapy remains to be determined.From January 2010 August 2013, was initiated 426 immune-mediated inflammatory diseases (IMIDs). Tuberculin skin test (TST) and Quantiferon-TB Gold In Tube (QFT-GIT) assay were performed starting treatment. defined as a positive TST...
We investigated the effects of corticosteroids on 90-day mortality outcomes in patients with pulmonary tuberculosis who were admitted to intensive care unit (ICU) because acute respiratory failure (ARF). The medical records 124 had ARF and ICU at our tertiary referral center South Korea between March 1989 December 2014 retrospectively analyzed. rate this population was analyzed after adjustments inverse probability treatment weighted (IPTW) method. mean patient age 62 years, 49.2% (61/124)....
Objectives This article focuses on the differences between CT findings of HIV-negative patients who have cavities with nontuberculous mycobacteria (NTM) disease and those Mycobacterium tuberculosis infections (TB). Methods We retrospectively reviewed 128 NTM (79 males 49 females) in chest CT, matched for age gender TB same period. Sputum cultures all were positive pathogens. Two independent radiologists evaluated characteristics largest cavity related factors. Results Interobserver agreement...
Although it is known that the in vitro MICs of rifampin and ethambutol are poorly correlated with clinical response Mycobacterium avium complex (MAC) lung disease (MAC-LD), evidence for this limited. This study investigated association between treatment outcome patients MAC-LD.
Abnormal body composition is an important modifiable risk factor in lung transplantation. Therefore, precise quantification of different components, including muscle and fat, may play role optimizing outcomes transplant patients. The purpose the study was to investigate prognostic significance subcutaneous fat mass measured on chest CT with regard transplantation survival other post-transplant outcomes.The population included 45 consecutive adult recipients (mean age 47.9 ± 12.1 years; 31...
Right heart decompensation is a fatal complication in patients with respiratory failure, particularly those transitioned to lung transplantation using veno-venous extracorporeal membrane oxygenation (V-V ECMO). In these patients, veno-arterial (V-A ECMO) or veno-arterialvenous (V-AV used support both cardiac and function. However, processes may increase the risk of device-related complications such as bleeding, thromboembolism, limb ischemia. present case, 64-year-old male patient idiopathic...