A5052088599- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Infectious Diseases and Mycology
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Diagnosis and treatment of tuberculosis
- Nutrition and Health in Aging
- Nutritional Studies and Diet
- Inflammatory Bowel Disease
- Pneumocystis jirovecii pneumonia detection and treatment
- Pancreatic and Hepatic Oncology Research
- Medical Research and Treatments
- Respiratory Support and Mechanisms
- Ginseng Biological Effects and Applications
- Photosynthetic Processes and Mechanisms
- Cardiac pacing and defibrillation studies
- Infectious Diseases and Tuberculosis
- Systemic Sclerosis and Related Diseases
- Transplantation: Methods and Outcomes
- Metabolomics and Mass Spectrometry Studies
- Neuroendocrine Tumor Research Advances
- Radiomics and Machine Learning in Medical Imaging
- Microscopic Colitis
- Gallbladder and Bile Duct Disorders
- Cancer, Hypoxia, and Metabolism
Severance Hospital
2015-2025
Yonsei University
2015-2025
Pusan National University Yangsan Hospital
2013-2025
Seoul National University of Education
2025
Pulmonary and Critical Care Associates
2024
Uijeongbu St. Mary's Hospital
2024
Kyungpook National University Hospital
2023
Gangnam Severance Hospital
2021-2022
Pusan National University Hospital
2020-2021
Center for Rheumatology
2018
Abstract Although tuberculosis (TB) is a severe health problem worldwide, the current diagnostic methods are far from optimal. Metabolomics increasingly being used in study of infectious diseases. We performed metabolome profiling to identify potential biomarkers patients with active TB. Serum samples 21 pulmonary TB, 20 subjects latent TB infection (LTBI), and 28 healthy controls were analyzed using liquid chromatography-tandem mass spectrometry (LC-MS/MS) followed by multivariate...
The longitudinal relationship between adiposity and lung function is controversial. We aimed to investigate the long-term association changes in a middle-aged general Asian population.In total, 5011 participants (average age, 54 years; 45% men) were enrolled from community-based prospective cohort. During follow-up period (median 8 years), both spirometry bio-electrical impedance analysis performed biannually. Individual slopes of fat mass index (FMI; divided by square height meters)...
Studies on the risk and protective factors for lung function decline mortality in rheumatoid arthritis-related interstitial disease (RA-ILD) are limited.We aimed to investigate clinical medication uses associated with RA-ILD.This retrospective cohort study examined medical records of patients RA-ILD who visited Severance Hospital between January 2006 December 2019. We selected 170 had undergone at least one spirometry test chest computed tomography scan. An absolute ⩾10% functional vital...
Systemic sclerosis (SSc) is a heterogeneous autoimmune disease characterized by dysregulation of fibroblast function, which often involves the lungs. Interstitial lung (ILD) associated with SSc (SSc-ILD) major cause death among patients SSc. Our study aimed to identify risk factors for mortality and compare clinical characteristics SSc-ILD.Patients were retrospectively enrolled between 2010 2018 in tertiary hospital Korea. Patients SSc-ILD classified depending on first pulmonary function...
Abstract Background Improving health-related quality of life (HRQOL) has emerged as a priority in the management nontuberculous mycobacterial pulmonary disease (NTM-PD). We aimed to evaluate HRQOL and its changes after 6 months’ treatment patients with NTM-PD. Methods The NTM-KOREA is nationwide prospective cohort enrolling initiating for NTM-PD 8 institutions across South Korea. conducted Quality Life–Bronchiectasis (QOL-B) at 6-month intervals evaluated baseline scores (higher indicate...
Coinfections with multiple nontuberculous mycobacterial (NTM) species have not been widely studied. We aimed to evaluate the clinical characteristics and treatment outcomes in patients NTM-pulmonary disease (PD) caused by coinfection NTM species.
Current research on nontuberculous mycobacteria (NTM) is multidisciplinary; thus, proper organization necessary to obtain comprehensive insights. Therefore, a bibliometric analysis was performed identify NTM characteristics in South Korea. The Web of Science searched for articles authored by Koreans at Korean institutions until March 2023. We collected data authors, publication year, article type, study design, area, citations, institutes, and funding sources analysis. Of the 28,092 NTM,...
Abstract Objectives Although it is recommended to close the zone of apposition (ZoA) as part repair atrioventricular septal defect (AVSD), had often been left untouched or significant mitral regurgitation (MR) ensued. Adult patients with previously incompletely closed open ZoA have more retracted and thickened edges due long standing MR. Combined annular dilatation, these factors aggravate MR consequently complicate surgical eventually leading valve replacement (MVR). In an effort overcome...
Abstract Background/Aims Evidence regarding the long-term association between hemoglobin (Hb) levels and lung function in individuals from general population is scarce. This study aimed to determine longitudinal Hb a community-based cohort South Korea. Methods We used linear mixed regression analysis evaluate associations parameters, including forced vital capacity (FVC), expiratory volume 1 s (FEV ), FEV /FVC. Additionally, we generalized estimating equation calculate odds ratio (OR) of...
Treatment with parenteral aminoglycosides is recommended for patients advanced Mycobacterium avium complex pulmonary disease (MAC-PD). However, the evidence supporting susceptibility-based treatment limited. We retrospectively reviewed MAC-PD treated at least eight weeks between October 2005 and December 2018 a tertiary referral center in South Korea. Patients without drug susceptibility test (DST) results were excluded. Among 951 diagnosed MAC-PD, 46 received six months of treatment,...
<title>Abstract</title> Background/Objectives: In the context of potential Korean unification, integrating South Korea’s robust but strained healthcare system with North resource-deficient framework presents significant challenges. This study explores public preferences for a unified system, focusing on generational and ideological factors. Methods A total 800 adults aged 19–59 were recruited using proportional quota sampling. Preferences perceptions unification necessity, expected personal...
The clinical staging of non-small cell lung cancer (NSCLC) is well known to be related their prognosis. However, there usually a discrepancy between and pathological staging. There are few analyses accuracy in patients with NSCLC. We compared the concordance rate NSCLC evaluated factors affecting real-world data.
Predicting outcomes in pulmonary tuberculosis is challenging despite effective treatments. This study aimed to identify factors influencing treatment success and culture conversion, focusing on artificial intelligence (AI)-based chest X-ray analysis Xpert MTB/RIF assay cycle threshold (Ct) values. In this retrospective across six South Korean referral centers (January 1 December 31, 2019), we included adults with rifampicin-susceptible confirmed by from sputum samples. We analyzed patient...
Lung function and depression are closely related to many chronic lung diseases. However, few studies have evaluated this association in the general population. In study, we relationship between population Korea.Data from Ansung-Ansan cohort, a community-based cohort Korea, were used analyze relationships parameters. A total of 3,321 men women aged 40-69 years enrolled. Spirometry data included forced expiratory volume 1 second (FEV1), vital capacity (FVC), FEV1/FVC ratio. Depression was...
Objectives Avascular necrosis (AVN) is one of the most common causes organ damage in patients with systemic lupus erythematosus (SLE) and often serious physical disability. The aims this study were to investigate clinical risk factors associated symptomatic AVN analyze their synergistic effects a large SLE cohort Korea. Methods Patients enrolled followed from 1998 2014 Hanyang BAE Lupus cohort, was measured annually according Systemic International Collaborating Clinics/American College...
Background/Aims The incidence rate of nontuberculous mycobacterial pulmonary disease (NTM-PD) is increasing worldwide. However, data regarding the age- and sex-specific epidemiology NTM-PD are limited. This study aimed to investigate long-term epidemiologic trends within recent 11-year period in a tertiary referral hospital Korea. Methods We retrospectively reviewed medical records patients diagnosed with between January 2006 December 2016 at Severance Hospital, South Results There were...
Sarcopenia is a well-established risk factor for atherosclerotic cardiovascular disease (ASCVD), but its relationship with chronic obstructive pulmonary (COPD) has not been fully determined. This study aimed to investigate the association between sarcopenia and ASCVD in patients COPD, independent of central obesity fat mass.Data regarding 704 men COPD (mean age: 63.4 years) were extracted from 2008 2011 Korean National Health Nutrition Examination Surveys. index mass assessed using...
Digital health technologies are widely used for disease management, with their computing platforms, software, and sensors being care. These developed to manage chronic diseases infectious bacterial diseases, including tuberculosis (TB).
The global prevalence and incidence of nontuberculous mycobacteria (NTM) infection are increasing. However, the NTM infection-associated comorbidities remains understudied. Thus, we investigated associated with using National Health Insurance Service-National Sample Cohort (NHIS-NSC) 2.0 database Service (NHIS).In this case-control study, patients controls aged 20-89 years age were matched 1:4 by sex, age, region, income. A total 26 selected based on previous reports claims data analysis....