A5026724471- Gut microbiota and health
- Cancer Immunotherapy and Biomarkers
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Lung Cancer Treatments and Mutations
- Sarcoidosis and Beryllium Toxicity Research
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Rheumatoid Arthritis Research and Therapies
- Urticaria and Related Conditions
- Brain Metastases and Treatment
- Lung Cancer Research Studies
- Drug-Induced Adverse Reactions
- Myasthenia Gravis and Thymoma
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Transplantation: Methods and Outcomes
- Mechanical Circulatory Support Devices
- Cancer Research and Treatments
- Genetic and Kidney Cyst Diseases
- Parkinson's Disease and Spinal Disorders
- Renal cell carcinoma treatment
- Helicobacter pylori-related gastroenterology studies
- Tuberous Sclerosis Complex Research
- Cardiac Structural Anomalies and Repair
- Lung Cancer Diagnosis and Treatment
Yonsei University
2021-2023
Severance Hospital
2021-2023
Chung-Ang University
2023
Seoul National University Bundang Hospital
2021
Abstract Background Lung cancer is the primary cause of cancer-related deaths worldwide. The human lung serves as a niche to unique and dynamic bacterial community that related development multiple diseases. Here, we investigated differences in microbiomes patients with cancer. Methods 16S rRNA sequencing was performed evaluate respiratory tract microbiome present bronchoalveolar lavage fluid. Patients were stratified based on programmed death-ligand 1 (PD-L1) expression levels immunotherapy...
Studies on the risk and protective factors for lung function decline mortality in rheumatoid arthritis-related interstitial disease (RA-ILD) are limited.We aimed to investigate clinical medication uses associated with RA-ILD.This retrospective cohort study examined medical records of patients RA-ILD who visited Severance Hospital between January 2006 December 2019. We selected 170 had undergone at least one spirometry test chest computed tomography scan. An absolute ⩾10% functional vital...
Incidence of complications related extracorporeal membrane oxygenation (ECMO) support as a bridge to lung transplantation (BTT) and its association with the patient outcome in (LT) has not been well documented previous studies.We evaluated incidence use ECMO BTT, between occurrence outcomes LTs.This retrospective cohort study investigated 100 consecutive patients who started BTT April 2013 March 2020. Data for analyses were retrieved from electronic medical records.Fifty-six percent...
Regarding whether brain magnetic resonance imaging (MRI) should be routine in patients with suspected early-stage lung cancer, guideline recommendations are inconsistent. Therefore, we performed this study to evaluate the incidence of and risk factors for metastasis (BM) non-small-cell cancer (NSCLC).A review medical charts consecutive NSCLC diagnosed between January 2006 May 2020 was performed. We identified 1,382 clinical staging T1/2aN0M0 (excluding BM), investigated incidence,...
Birt–Hogg–Dube (BHD) is a rare genetic disorder characterized by multiple lung cysts, typical skin manifestations, and renal tumors. We prospectively enrolled thirty-one subjects from four South Korean institutions with next-generation sequencing was conducted. cysts. Next-generation performed to investigate mutations in the following genes: FLCN, TSC1, TSC2, CFTR, EFEMP2, ELN, FBLN5, LTBP4, SERPINA1. BHD diagnosed 11 of 31 (35.5%; FLCN mutations). Notably, we identified three novel...
There is no validated clinical biomarker for disease severity or treatment response nontuberculous mycobacterial pulmonary (NTM-PD). We investigated the correlation between elevated serum carbohydrate antigen (CA) 19-9 levels and NTM-PD activity, defined using an imaging score based on chest computed tomography (CT). retrospectively examined 79 patients with who underwent CA19-9 level assessments CT less than 1 month apart. was rated a CT-based scoring system. The evaluated. Chest revealed...
Abstract Background: Lung cancer is the primary cause of cancer-related deaths worldwide. The human lung serves as a niche to unique and dynamic bacterial community that related development multiple diseases. Here, we investigated differences in microbiomes patients with cancer. Methods: 16S rRNA sequencing was performed evaluate respiratory tract microbiome present bronchoalveolar lavage fluid. Patients were stratified based on programmed death-ligand 1 (PD-L1) expression levels...
Myasthenic crisis, which can be life-threatening due to severe respiratory failure, occurs in 15-20% of patients with myasthenia gravis. However, the crisis often develops within 1-2 years after diagnosis and is very rare as a first symptom gravis; isolated sudden-onset hypercapnic failure without other symptoms gravis even rarer. A 63-year-old woman presented emergency department fever dizziness. Chest computed tomography showed multifocal peribronchial ground-glass opacities, pneumonia was...