A5100388390- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
- Lung Cancer Diagnosis and Treatment
- COVID-19 Clinical Research Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Tracheal and airway disorders
- Pneumonia and Respiratory Infections
- COVID-19 diagnosis using AI
- Sepsis Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Respiratory Support and Mechanisms
- Infectious Diseases and Mycology
- Digital Marketing and Social Media
- Consumer Behavior in Brand Consumption and Identification
- Long-Term Effects of COVID-19
- Emergency and Acute Care Studies
- Inhalation and Respiratory Drug Delivery
- Asthma and respiratory diseases
- Cystic Fibrosis Research Advances
- Consumer Perception and Purchasing Behavior
- Lung Cancer Treatments and Mutations
- Medical Imaging and Pathology Studies
- Antibiotic Resistance in Bacteria
- Cardiac Arrest and Resuscitation
- Neonatal Respiratory Health Research
Seoul National University Bundang Hospital
2016-2025
Korea Advanced Institute of Science and Technology
2025
Seoul National University
2016-2024
Samsung Medical Center
2024
Sungkyunkwan University
2024
Korea Disease Control and Prevention Agency
2023
Seoul National University Hospital
2015-2023
Ewha Womans University
2021-2023
Armed Forces Capital Hospital
2019-2022
Yonsei University
2022
In the development of autonomous vehicles, main focus sensor research has been in relation to environmental perception, and only minimal work focused on human-vehicle interaction perspective. However, human factors need be considered ensure safe operation partially vehicles. This study briefly introduces a design methodology for takeover request (TOR) time National Highway Traffic Safety Administration Level 3 vehicles compares four different TORs simulated environment based...
Rationale: Because the prognosis of nontuberculous mycobacterial pulmonary disease varies, a scoring system predicting mortality is needed.Objectives: We aimed to develop novel predict among patients with disease.Methods: included age ≥20 years newly diagnosed disease, Mycobacterium avium, M. intracellulare, abscessus subsp. abscessus, or massiliense. Cox proportional hazards models were used identify predictors in derivation cohort, and was developed. It validated an independent prospective...
Background Prioritizing patients in need of intensive care is necessary to reduce the mortality rate during COVID-19 pandemic. Although several scoring methods have been introduced, many require laboratory or radiographic findings that are not always easily available. Objective The purpose this study was develop a machine learning model predicts for with using obtainable characteristics—baseline demographics, comorbidities, and symptoms. Methods A retrospective performed nationwide cohort...
Radotinib (IY5511HCL), a novel and selective BCR-ABL1 tyrosine kinase inhibitor, has shown pre-clinical phase I activity safety in chronic myeloid leukemia. This II study investigated the efficacy of radotinib Philadelphia chromosome-positive phase-chronic leukemia patients with resistance and/or intolerance to inhibitors. Patients received 400 mg twice daily for 12 cycles based on results from trial. The primary end point was rate major cytogenetic response by months. A total 77 were...
A three-drug regimen (macrolide, ethambutol, and rifampicin) is recommended for the treatment of Mycobacterium avium complex pulmonary disease (MAC-PD). Although macrolide has proven efficacy, role ethambutol rifampicin in patients without acquired immune deficiency syndrome not with clinical studies. We aimed to clarify roles MAC-PD.Patients treated MAC-PD between March 1st, 2009 October 31st, 2018 were reviewed retrospectively. Rates culture conversion, microbiological cure, failure,...
Lung cancers presenting as subsolid nodule commonly have peripheral location, making the cancer-pleura relationship noteworthy. We aimed to evaluate effect of pleural attachment and/or indentation on visceral invasion (VPI) and recurrence-free survival.Patients who underwent curative resection lung cancer nodules from April 2007 January 2016 were retrospectively evaluated. They divided into four groups according their with pleura. Clinical, radiographical, pathological findings...
Abstract Background Unavailability or saturation of the intensive care unit may be associated with fatality COVID-19. Prioritizing patients for hospitalization and critical reducing This study aimed to develop validate a new integer-based scoring system predicting COVID-19 requiring care, using only predictors available upon triage. Methods is retrospective cohort data from Korean Centers Disease Control Prevention that included all admitted between January 19 June 3, 2020, in South Korea....
This study leverages the Global/Regional Integrated Model system (GRIMs) version 4.0 climate model to examine mechanisms behind recent intensification of winter stationary waves over western North America. Prescribed sea surface temperature warming forces a strengthening westerly winds, amplifying ridge that characterizes in The streamfunction budget analysis reveals relative vorticity advection is mainly associated with this process. We further show ocean primary driver changes winds and...
This paper critically explores the life and influence of Pastor Kyu-Oh Chung, a seminal figure in Korean Presbyterianism, who embodied Reformed theology through his ministry, leadership, academic contributions, socio-political engagement, with particular focus on advocacy for justice within broader context Korea. Chung’s 92-year journey (1914– 2006) is assessed across five dimensions i.e., as lay leader, pastor, influential religious figure, administrator, family head. His went far beyond...
A uniform prognostic marker is needed for nontuberculous mycobacterial pulmonary disease (NTM-PD) due to the diverse clinical course. We aimed seek utility of BACES score, originally derived predict all-cause mortality, various outcomes. To calculate one point was given each following factors: body mass index < 18.5 kg/m2, age ≥ 65 years, presence cavities, elevated erythrocyte sedimentation rate, or male sex. The study included 681 patients, whom 97 (14.2%), 189 (27.7%), 192 (28.2%), 143...
Oxidative stresses from irritants such as hydrogen peroxide and ozone (O3) can cause dysfunction of the pulmonary surfactant (PS) layer in human lung, resulting chronic diseases respiratory tract. For identification structural changes protein B (SP-B) due to heterogeneous reaction with O3, field-induced droplet ionization (FIDI) mass spectrometry has been utilized. FIDI is a soft method which ions are extracted surface microliter-volume droplets. We report structurally specific oxidative...
The impact on patient mortality of combined pulmonary fibrosis and emphysema (CPFE) compared with alone has never been investigated.To elucidate whether CPFE an overall over that alone.We screened patients who underwent chest computed tomography (CT) scans during the period from 1 January 2001 to 31 December 2005 in a tertiary referral hospital. Patients had both fibrosis, thus meeting inclusion criteria, were defined as CPFE. Controls matched for age, sex date CT scan randomly selected. Cox...
Abstract Background Bacterial colonization is an essential aspect of bronchiectasis. Although Haemophilus influenzae a frequent colonizer in some regions, its clinical impacts are poorly understood. This study aimed to elucidate the impact H. patients with Methods retrospective screened adult diagnosed bronchiectasis at tertiary referral center between April 1, 2003, and May 16, 2021, South Korea. Propensity score matching was used match without colonization. We assessed severity as per...
Abstract Background Improving health-related quality of life (HRQOL) has emerged as a priority in the management nontuberculous mycobacterial pulmonary disease (NTM-PD). We aimed to evaluate HRQOL and its changes after 6 months’ treatment patients with NTM-PD. Methods The NTM-KOREA is nationwide prospective cohort enrolling initiating for NTM-PD 8 institutions across South Korea. conducted Quality Life–Bronchiectasis (QOL-B) at 6-month intervals evaluated baseline scores (higher indicate...
Abstract Background The close association between bronchiectasis and nontuberculous mycobacterial pulmonary disease (NTM-PD) is well-known. However, the clinical impact of subsequent new-onset NTM-PD in patients has not been elucidated. aim this study to investigate courses radiographic changes with whom subsequently developed. Methods A total 221 who had participated a non-NTM cohort July 1st 2011 August 31st 2019 at Seoul National University Hospital were included study. data developed...
Abstract Infection is associated with occurrence and worsening of heart failure (HF). However, studies on the association susceptibility severe complications coronavirus disease 2019 (COVID‐19) HF history are limited. From Korean nationwide COVID‐19 data set, 212,678 participants at least one acute respiratory syndrome 2 real‐time reverse transcription polymerase chain reaction (RT‐PCR) test were included between January 1 June 4, 2020. To investigate COVID‐19, 1:4 ratio propensity score...
Administration of adequate antibiotics is crucial for better outcomes in sepsis. Because no uniform tool can accurately assess the risk multidrug-resistant (MDR) pathogens, a local antibiogram necessary. We aimed to describe MDR bacteria based on locations sepsis onset South Korea.We performed prospective observational study adult patients diagnosed with according Sepsis-3 from 19 institutions (13 tertiary referral and 6 university-affiliated general hospitals) Korea. Patients were divided...
Chronic obstructive pulmonary disease (COPD) is associated with increased postoperative complications. Recently, the Global Initiative for Obstructive Lung Disease (GOLD) classified COPD patients into four groups based on spirometry results and severity of symptoms. The objective this study was to evaluate impact GOLD complications.We reviewed medical records who underwent preoperative between April August 2013 at a tertiary hospital in Korea. We divided according self-administered...
Predicting outcomes in pulmonary tuberculosis is challenging despite effective treatments. This study aimed to identify factors influencing treatment success and culture conversion, focusing on artificial intelligence (AI)-based chest X-ray analysis Xpert MTB/RIF assay cycle threshold (Ct) values. In this retrospective across six South Korean referral centers (January 1 December 31, 2019), we included adults with rifampicin-susceptible confirmed by from sputum samples. We analyzed patient...