A5000044735- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- COVID-19 diagnosis using AI
- Atrial Fibrillation Management and Outcomes
- COVID-19 Clinical Research Studies
- Peripheral Artery Disease Management
- Cardiovascular Health and Disease Prevention
- Sepsis Diagnosis and Treatment
- Artificial Intelligence in Healthcare and Education
- Traumatic Brain Injury and Neurovascular Disturbances
- Healthcare Systems and Practices
- Telemedicine and Telehealth Implementation
- Intracranial Aneurysms: Treatment and Complications
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Imaging and Diagnostics
- Medical and Biological Sciences
- Aortic Thrombus and Embolism
- Mobile Health and mHealth Applications
- Advanced X-ray and CT Imaging
- Radiomics and Machine Learning in Medical Imaging
- Machine Learning in Healthcare
- Blood Pressure and Hypertension Studies
- Digital Mental Health Interventions
Yonsei University
2016-2025
Gangnam Severance Hospital
2016-2024
Severance Hospital
2022-2024
Hallym University
2024
Sungkyunkwan University
2024
Wonju Severance Christian Hospital
2024
Keimyung University
2024
Armed Forces Capital Hospital
2020-2022
Ministry of National Defense
2021
Armed Forces Medical College
2020
Background and Purpose- The prediction of long-term outcomes in ischemic stroke patients may be useful treatment decisions. Machine learning techniques are being increasingly adapted for use the medical field because their high accuracy. This study investigated applicability machine to predict patients. Methods- was a retrospective using prospective cohort that enrolled with acute stroke. Favorable outcome defined as modified Rankin Scale score 0, 1, or 2 at 3 months. We developed models...
Importance Optimal blood pressure (BP) control after successful reperfusion with endovascular thrombectomy (EVT) for patients acute ischemic stroke is unclear. Objective To determine whether intensive BP management during the first 24 hours leads to better clinical outcomes than conventional in who underwent EVT. Design, Setting, and Participants Multicenter, randomized, open-label trial a blinded end-point evaluation, conducted across 19 centers South Korea from June 2020 November 2022...
Background Prioritizing patients in need of intensive care is necessary to reduce the mortality rate during COVID-19 pandemic. Although several scoring methods have been introduced, many require laboratory or radiographic findings that are not always easily available. Objective The purpose this study was develop a machine learning model predicts for with using obtainable characteristics—baseline demographics, comorbidities, and symptoms. Methods A retrospective performed nationwide cohort...
Sarcopenia, a age-related disease characterized by loss of muscle mass accompanied function, is associated with nutrition imbalance, physical inactivity, insulin resistance, inflammation, metabolic syndrome, and atherosclerosis which are risk factors for cardiovascular disease. However, its association outcomes after ischemic stroke has not been well-established. This study investigated whether functional patients acute sarcopenia.Data were collected from 568 consecutive National Institute...
This study aimed to investigate whether there was a difference in one-year outcome after stroke between patients treated with antiplatelet and anticoagulation (OAC + antiplatelet) those only (OAC), when comorbid atherosclerotic disease present non-valvular atrial fibrillation (NVAF). retrospective using prospective cohort of consecutive ischemic stroke. Patients NVAF were assigned the OAC or group based on discharge medication. All-cause mortality, recurrent stroke, hemorrhagic myocardial...
Abstract Background Unavailability or saturation of the intensive care unit may be associated with fatality COVID-19. Prioritizing patients for hospitalization and critical reducing This study aimed to develop validate a new integer-based scoring system predicting COVID-19 requiring care, using only predictors available upon triage. Methods is retrospective cohort data from Korean Centers Disease Control Prevention that included all admitted between January 19 June 3, 2020, in South Korea....
Background The purpose of the RAFAS (Risk and Benefits Urgent Rhythm Control Atrial Fibrillation in Patients With Acute Stroke) trial was to explore risks benefits early rhythm control patients with newly documented atrial fibrillation (AF) during an acute ischemic stroke (IS). Method Results An open‐label, randomized, multicenter design used. If AF diagnosed, group started within 2 months after occurrence IS, unlikely usual care. primary end points were recurrent IS 3 12 months. secondary a...
The effects of blood pressure (BP) lowering in patients treated with intravenous tissue plasminogen activator (IV tPA) before endovascular thrombectomy (EVT) are unclear. This study aims to investigate whether intensive and conventional BP management affect outcomes differently, depending on IV tPA administration EVT. In this subgroup analysis the Outcome Patients Treated Intra-Arterial Thrombectomy-Optimal Blood Pressure Control (OPTIMAL-BP; ClinicalTrials.gov Identifier: NCT04205305)...
Introduction: The link between arterial stiffness, measured by estimated pulse wave velocity (ePWV), and outcomes following endovascular treatment (EVT) is unclear. Hypothesis: This study aimed to determine whether ePWV predicts post-EVT outcome in patients with acute ischemic stroke. Methods: was a secondary analysis of the OPTIMAL-BP trial, which enrolled 302 EVT from 19 stroke centers Korea June 18, 2020 November 28, 2022. calculated using regression equation based on age mean blood...
This report provides an overview of hypertension prevalence, management, and trends in South Korea. The analysis is based on data from Korean adults aged 20 older, using the 1998-2022 Korea National Health Nutrition Examination Survey (KNHANES) 2002-2022 Insurance (NHI) Big Data. An estimated 30% (13 million) have hypertension, including 7.2 million men, 5.8 women, 65 or older. Overall awareness, treatment, control rates were 77%, 74%, 59%, respectively, showing a tendency to increase with...
BACKGROUND The link between arterial stiffness, measured by estimated pulse wave velocity (ePWV), and outcomes following endovascular thrombectomy (EVT) has not been tested. This study aimed to determine whether ePWV predicts post‐EVT outcome in patients with acute ischemic stroke. METHODS was a secondary analysis of the OPTIMAL‐BP (Outcome Patients Treated With Intraarterial Thrombectomy–Optimal Blood Pressure Control) trial, which enrolled 302 EVT from 19 stroke centers South Korea June...
Patients with acute stroke are often accompanied by comorbidities, such as active cancer. However, adequate treatment guidelines not available for these patients. The purpose of this study was to evaluate the association between cancer and outcomes reperfusion therapy in patients stroke.We compared who underwent therapy, using a nationwide registry. We divided into 3 groups according activity: cancer, nonactive without history investigated processes, 24-hour neurological improvement, adverse...
Importance The associations between blood pressure (BP) decreases induced by medication and functional outcomes in patients with successful endovascular thrombectomy remain uncertain. Objective To evaluate whether BP reductions intravenous medications are associated poor at 3 months. Design, Setting, Participants This cohort study was a post hoc analysis of the Outcome Patients Treated With Intra-Arterial Thrombectomy–Optimal Blood Pressure Control trial, comparison intensive conventional...
The benefits of thrombolytic treatment are time-dependent. We developed a smartphone application that aids stroke patient self-screening and hospital selection, may also decrease arrival time.The was for iPhone Android smartphones. Map data the were adopted from open map. For registration, web page (http://stroke119.org) using PHP MySQL.The Stroke 119 includes screening tool real-time information on nearby hospitals provide treatment. It provides symptoms, treatment, prescribed actions when...
A machine learning technique for identifying hidden coronary artery disease (CAD) might be useful. We developed and validated models to predict patients with CAD assess long-term outcomes in acute ischemic stroke.Multidetector CT was performed without a known history of CAD. Primary were defined as having any degree obstructive (≥50% stenosis). Demographic variables, risk factors, laboratory results, Trial ORG 10172 Acute Stroke Treatment classification, NIH Scale score, blood pressure,...
Understanding the factors related to early neurologic deterioration (END) is crucial in management of patients with lacunar infarction. Blood viscosity a significant factor for microvascular perfusion. We investigated association between blood and occurrence END infarction.We included consecutive admitted infarction within 72 h from symptoms onset. was defined as an increase National Institute Health Stroke Scale (NIHSS) score ≥2 24 admission. Viscosity measured hospitalization scanning...
We aimed to develop and validate machine learning models diagnose patients with ischemic stroke cancer through the analysis of histopathologic images thrombi obtained during endovascular thrombectomy.This was a retrospective study using prospective multicenter registry which enrolled consecutive acute from South Korea who underwent thrombectomy. This included admitted between July 1, 2017 December 31, 2021 6 academic university hospitals. Whole-slide scanning performed for...
Abstract The prognosis of patients with embolic stroke undetermined source (ESUS) may vary according to the underlying cause. Therefore, we aimed divide ESUS into subtypes and assess long-term outcomes. Consecutive acute ischemic who underwent a comprehensive workup, including transesophageal echocardiography prolonged electrocardiography monitoring, were enrolled. We classified minor cardioembolic (CE) ESUS, arteriogenic two or more causes no cause ESUS. Arteriogenic was sub-classified...
Background COVID-19 has officially been declared as a pandemic, and the spread of virus is placing sustained demands on public health systems. There are speculations that mortality differences between regions due to disparities in availability medical resources. Therefore, selection patients for diagnosis treatment essential this situation. Military personnel especially at risk infectious diseases; thus, patient with an evidence-based prognostic model critical them. Objective This study aims...
Background and Purpose We aimed to develop a model predicting early recanalization after intravenous tissue plasminogen activator (t-PA) treatment in large-vessel occlusion.Methods Using data from two different multicenter prospective cohorts, we determined the factors associated with immediately t-PA stroke patients occlusion, developed validated prediction for recanalization. Clot volume was semiautomatically measured on thin-section computed tomography using software, degree of...