Background Prioritizing patients in need of intensive care is necessary to reduce the mortality rate during COVID-19 pandemic. Although several scoring methods have been introduced, many require laboratory or radiographic findings that are not always easily available. Objective The purpose this study was develop a machine learning model predicts for with using obtainable characteristics—baseline demographics, comorbidities, and symptoms. Methods A retrospective performed nationwide cohort...

Abstract Background Unavailability or saturation of the intensive care unit may be associated with fatality COVID-19. Prioritizing patients for hospitalization and critical reducing This study aimed to develop validate a new integer-based scoring system predicting COVID-19 requiring care, using only predictors available upon triage. Methods is retrospective cohort data from Korean Centers Disease Control Prevention that included all admitted between January 19 June 3, 2020, in South Korea....

Abstract: Many patients suffering from asthma or COPD have overlapping features of both diseases. However, a phenotypical approach for evaluating asthma–COPD overlap syndrome (ACOS) has not been established. In this report, we examined the phenotypes in with ACOS. Patients diagnosed ACOS between 2011 and 2015 were identified ­classified into four phenotype groups. Group A was composed who smoked <10 pack years had blood eosinophil counts ≥300. B <300. C ≥10 D Clinical characteristics...

Background COVID-19 has officially been declared as a pandemic, and the spread of virus is placing sustained demands on public health systems. There are speculations that mortality differences between regions due to disparities in availability medical resources. Therefore, selection patients for diagnosis treatment essential this situation. Military personnel especially at risk infectious diseases; thus, patient with an evidence-based prognostic model critical them. Objective This study aims...

Little clinical information on high grade tuberculosis destroyed lung (TDL) is available. The aim of this study was to investigate the characteristics and healthcare utilization TDL patients, compared differences between acute exacerbation burden according inhaler compliance.This an observational retrospective cohort using Korean Health Insurance Review Assessment (HIRA) service database (2011-2015). Patients diagnosed with in 2011 were enrolled reviewed for 5 years. patients further divided...

Background Roflumilast is the only approved oral phosphodiesterase-4 inhibitor for treatment of severe chronic obstructive pulmonary disease (COPD) in patients with bronchitis and a history frequent exacerbations. The purpose this study was to examine incidence adverse effects associated roflumilast real-world setting. Further, we compared discontinuation rate among receiving different doses. Methods We identified all outpatients diagnosed COPD at Seoul St. Mary's Hospital between May 2011...

Background Clear guidelines for a patient with suspected COVID-19 infection are unavailable. Many countries rely on assessments through national hotline or telecommunications, but this only adds to the burden of an already overwhelmed health care system. In study, we developed algorithm and web application help patients get screened. Objective This study aims aid general public by developing web-based that helps decide when seek medical during novel disease outbreak. Methods The was via...

Brain parenchymal metastasis from a solid tumor is serious clinical condition associated with poor outcome because systemic chemotherapy usually ineffective for treating brain metastases (BM) due to the blood-brain barrier. Therefore, radiotherapy such as whole (WBRT) and stereotactic radiosurgery have taken on central role in management of BM. However, WBRT can delay subsequent treatment or cause neurologic complications decline cognitive function. suspending worth considering if there an...

We previously developed learning models for predicting the need intensive care and oxygen among patients with coronavirus disease (COVID-19). Here, we aimed to prospectively validate accuracy of these models.Probabilities [intensive unit (ICU) score] (oxygen score) were calculated from information provided by hospitalized COVID-19 (n=44) via a web-based application. The performance baseline scores predict 30-day outcomes was assessed.Among 44 patients, 5 15 needed oxygen, respectively. area...

The computer-aided diagnosis (CAD) for chest X-rays was developed more than 50 years ago. However, there are still unmet needs its versatile use in our medical fields. We planned this study to develop a multipotent CAD model suitable general including primary care areas. solve the problem by using computed tomography (CT) scan with one-to-one matched X-ray dataset. data extracted and preprocessed pulmonology experts bounding boxes locate lesions of interest. For detecting multiple lesions,...

Pulmonary capillary hemangiomatosis (PCH) is a progressive and refractory vascular disease in the lung. hypertension frequently combined with PCH when proliferation invades to nearby pulmonary systems. It difficult differentiate from other diseases such as venoocclusive arterial that cause they overlap. A 29-year-old female who had worked at bathtub factory presented exertional dyspnea for past 2 years. Computed tomography revealed centrilobular, diffusely spreading ground-glass opacities...

Abstract Background Unavailability or saturation of the intensive care unit may be associated with fatality COVID-19. Prioritizing patients for hospitalization and critical reducing This study aimed to develop validate a new integer-based scoring system predicting COVID-19 requiring care, using only predictors available upon triage. Methods is retrospective cohort data from Korean Centers Disease Control Prevention that included all admitted between January 19 June 3, 2020, in South Korea....

Primary intracranial germ cell tumor (GCT) is a rare that generally occurs due to developmental anomaly. Although GCT sensitive treatment, high recurrence rate, treatment-related long-term complications and the heterogeneity of this group make treatment complicated. Moreover, because its location, hydrocephalus visual field defect, functional disturbance pituitary gland can occur require attention. Treatment primarily relies on chemotherapy radiation therapy but management remains unsettled,...

Progress in the development of DNA vaccines and their delivery strategies has been made since initial concept as a next generation vaccine. Since vaccine includes non-infectious parts pathogens, it can't cause disease yet closely mimic natural process infection immune responses. Despite early promising results controlling infectious diseases cancer small animal models, failed to display level immunogenicity required for combating these humans, possibly due lower protein expression levels....

Portal vein thrombosis is an uncommon but important cause of portal hypertension. The most common etiological factors are liver cirrhosis and malignancy. Albeit rare, can also occur in the presence local infection inflammation such as pancreatitis or cholecystitis. A 52-year-old male was admitted because general weakness poor oral intake. He had operation for colon cancer 18 months ago. However, colonic stent to be inserted afterwards stricture developed at anastomosis site. Computed...

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Acute eosinophilic pneumonia (AEP) is common among military smokers; however, bronchoscopy required for the diagnosis. We aimed to derive and validate a scoring system diagnose AEP without bronchoscopy.We conducted retrospective study including patients diagnosed with or any other smokers hospitalized in Armed Forces Capital Hospital from 15 November 2016 through 25 December 2019. The were divided into derivation validation groups according their admission day. Patient symptoms, laboratory...

Background/Aims: The natural history of severe erosive reflux disease in Korea remains uncertain.We aimed to evaluate endoscopic follow-up results subjects with esophagitis under routine clinical care.Materials and Methods: A total 61,891 underwent an upper examination the health check-up program from January 2007 December 2013.We reviewed medical charts patients who had been diagnosed esophagitis.The severity was determined by Los Angeles (LA) classification system.Patients at least one...

EunJin Kang, Su-Jin Moon, Kyung ho Deok-jae Han, Jain Lee, Sang Mi Ro, Jang-Won Son, Sung-Rae Kim, Jun-Ki Min, and Soon Jib Yoo. Korean J Obes 2016;25:150-3. https://doi.org/10.7570/kjo.2016.25.3.150