A5069410715- Ocular Surface and Contact Lens
- Marine and fisheries research
- Retinal Imaging and Analysis
- Corneal surgery and disorders
- Glaucoma and retinal disorders
- Global trade and economics
- Marine Bivalve and Aquaculture Studies
- Cervical Cancer and HPV Research
- Statistical Distribution Estimation and Applications
- Economic Growth and Productivity
- Corneal Surgery and Treatments
- Global Health and Surgery
- Ophthalmology and Visual Impairment Studies
- Intraocular Surgery and Lenses
- Global Health Workforce Issues
- Fish Ecology and Management Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Drug-Induced Adverse Reactions
- Economic Growth and Development
- Mobile Health and mHealth Applications
- Influenza Virus Research Studies
- Evaluation and Performance Assessment
- ICT Impact and Policies
- Retinal Diseases and Treatments
- International Business and FDI
Yonsei University
2016-2025
Re-shaping Development Institute
2024
Cal Humanities
2021-2024
Yonsei University Health System
2021-2024
Harvard University
2021-2023
University of Warmia and Mazury in Olsztyn
2022
Charité - Universitätsmedizin Berlin
2022
Instituto Politécnico de Lisboa
2022
Universidade Nova de Lisboa
2022
Hospital Posadas
2022
Abstract Visually impaired and blind people due to diabetic retinopathy were 2.6 million in 2015 estimated be 3.2 2020 globally. Though the incidence of is expected decrease for high-income countries, detection treatment it early stages are crucial low-income middle-income countries. Due recent advancement deep learning technologies, researchers showed that automated screening grading efficient saving time workforce. However, most automatic systems utilize conventional fundus photography,...
Moyamoya disease (MMD) is a rare and complex pathological condition characterized by an abnormal collateral circulation network in the basal brain. The diagnosis of MMD its progression unpredictable influenced many factors. can affect blood vessels supplying eyes, resulting range ocular symptoms. In this study, we developed deep learning model using real-world data to assist determine stage retinal photographs.
Stevens-Johnson syndrome (SJS) and its severe variant, toxic epidermal necrolysis (TEN), are acute inflammatory vesiculobullous reactions of the skin mucous membranes. Cold medicines including non-steroidal anti-inflammatory drugs multi-ingredient cold medications reported to be important inciting drugs. Recently, we that medicine related SJS/TEN (CM-SJS/TEN) with mucosal involvement ocular surface complications (SOC) is associated HLA-A*02:06 HLA-B*44:03 in Japanese. In this study,...
Abstract Realistic image synthesis based on deep learning is an invaluable technique for developing high-performance computer aided diagnosis systems while protecting patient privacy. However, training a generative adversarial network (GAN) remains challenging because of the large amounts data required various kinds features. This study aims to synthesize retinal images indistinguishable from real and evaluate efficacy synthesized having specific disease augmenting class imbalanced datasets....
Importance Screening for autism spectrum disorder (ASD) is constrained by limited resources, particularly trained professionals to conduct evaluations. Individuals with ASD have structural retinal changes that potentially reflect brain alterations, including visual pathway abnormalities through embryonic and anatomic connections. Whether deep learning algorithms can aid in objective screening symptom severity using photographs unknown. Objective To develop ensemble models differentiate...
Attention-deficit/hyperactivity disorder (ADHD), characterized by diagnostic complexity and symptom heterogeneity, is a prevalent neurodevelopmental disorder. Here, we explored the machine learning (ML) analysis of retinal fundus photographs as noninvasive biomarker for ADHD screening stratification executive function (EF) deficits. From April to October 2022, 323 children adolescents with were recruited from two tertiary South Korean hospitals, age- sex-matched individuals typical...
Abstract High-mobility group box 1 (HMGB1) functions as a transcription-enhancing nuclear protein well crucial cytokine that regulates inflammation. This study demonstrated secretion of HMGB1 due to ultraviolet (UV) radiation inducing ocular surface inflammation-mediated reactive oxygen species (ROS) production. After treating conjunctival epithelial cells with UV radiation, was translocated from the nucleus cytoplasm and then eventually extracellular space. played role in UV-induced...
The eye route has been evaluated as an efficient vaccine delivery routes. However, in order to induce sufficient antibody production with inactivated vaccine, testing of the safety and efficacy use antigen plus adjuvant is needed. Here, we assessed various types adjuvants eyedrop anti-influenza serum mucosal Ab production-enhancer BALB/c mice. Among adjuvants, poly (I:C) showed much enhancement antigen-specific IgG IgA cholera toxin (CT) after vaccinations trivalent hemagglutinin-subunits or...
We investigated whether eyedrop vaccination using modified outer membrane vesicles (mOMVs) is effective for protecting against hemolytic uremic syndrome (HUS) caused by enterohemorrhagic E. coli (EHEC) O157:H7 infection. Modified OMVs and waaJ-mOMVs were prepared from cultures of MsbB- Shiga toxin A subunit (STxA)-deficient EHEC bacteria with or without an additional waaJ mutation. BALB/c mice immunized mOMVs, waaJ-mOMVs, mOMVs plus polymyxin B (PMB). Mice boosted at 2 weeks, challenged...
Background Human papillomavirus (HPV) can cause cancers in men and women. Despite the availability of an effective vaccine, HPV vaccination coverage remains suboptimal among college students. Literature showed that hesitancy for is a leading barrier to uptake this group. However, prior interventions have shown limitations reducing vaccine Thus, study examined conventional educational approach using information statement (VIS), subsequently explored students’ potential virtual reality (VR)...
To investigate changes in the pain-suppressing potency of 2 preoperatively applied topical nonsteroidal antiinflammatory drugs (NSAIDs) after photorefractive keratectomy (PRK) using a time-serial pain-scoring system.Saeyan Eye Center, Seoul, South Korea.Comparative case series.Ninety-four patients were randomly assigned to groups: ketorolac group (ketorolac 0.5% 1 eye and ofloxacin 0.3% other eye) diclofenac (diclofenac 0.1% eye). One drop each ophthalmic drug was 3 times 30 minutes before...
To investigate conditions that cause temporal lens opacity, we tested chemical and physical factors, such as anaesthesia dose, ocular surface dryness, infrared (IR) light exposure in anaesthetised C57BL/6 N mice. Mice were with a low (80%; tiletamine/zolazepam 32 mg/kg xylazine 8 mg/kg, intraperitoneal injection) or high (120%; 48 12 mg/kg) dose of anaesthetic examined every 5 min from 10 to 30 after was induced. Lens opacity levels assessed graded (1-6) using the standard classification...
Objective The effectiveness of health education on adolescents has been questioned, along with a growing body empirical studies documenting the absence behavioral changes after intervention. However, evidence its impact other crucial domains, besides practices, is lacking. We evaluated causal effects school-based program adolescents’ multidimensional psychological factors. Design A cluster-randomized controlled trial. Methods conducted trial involving 140 lower secondary schools in Vietnam....
Purpose: This purpose of this report was to study trends in cataract and refractive surgeries conducted during the past twelve years compare results previous reports from ASCRS New Zealand (NZ) order forecast future medical services.Methods: We surveyed members Korean Society Cataract Refractive Surgery (KSCRS) every year 1995 2006, studied changes (RS).Results: The duration hospitalization has been gradually decreasing point that a one day following surgery become common.The rate topical...
Purpose The purpose of this paper is to examine an endogenous growth model, as a component broader study servicization with skill premium and its policy implications in the evolving digital economy. Design/methodology/approach This develops two-sector model which allows for observed characteristics digitally empowered structural changes. Specifically, driving force economic expanding variety intermediate services consequence innovation services. introduction new specifically contributes...
To demonstrate that ultraviolet-A (UV-A) and voriconazole combination therapy is more effective than single treatment for fungal keratitis.The in vitro UV-A (375 nm) fungicidal effect was evaluated on Fusarium solani solutions. Each solution irradiated with different irradiation doses. Also, a containing also UV-A. The vivo therapeutic of studied rabbit keratitis model. Fungi were injected intrastromally into the cornea 16 rabbits. initiated 3 days after injection continued up to 8 following...
The use of organic light-emitting diodes (OLEDs) has rapidly increased in recent years. However, the effect OLEDs on human health not been studied yet. We investigated morphologic and functional changes after exposure ocular cells, including corneal, conjunctival, lens, retinal pigment epithelial mouse eyes. In corneal conjunctival levels reactive oxygen species production interleukin-8 expression white (LED) were significantly greater than those OLED exposure. Although no gross eyelid or...
Background Clear guidelines for a patient with suspected COVID-19 infection are unavailable. Many countries rely on assessments through national hotline or telecommunications, but this only adds to the burden of an already overwhelmed health care system. In study, we developed algorithm and web application help patients get screened. Objective This study aims aid general public by developing web-based that helps decide when seek medical during novel disease outbreak. Methods The was via...
The objective of this paper is to provide an overview the World Health Organization - International Telecommunication Union MyopiaEd programme a digital message targeting education on myopia and its prevention. development included 4 key steps: (1) Conceptualization consultation with experts in field myopia, mHealth health behavior change; (2) Creation SMS libraries algorithm; (3) Review ensure relevance target audience; (4) Pre-testing amongst end-user groups that design content were...
바지락 (Ruditapes philippinarum) 은 모래와 진흙이 많은 연안에 주로 분포하지만 드물게 울산의 태화강처럼 하천의 중류나 하류에서도 분포한다. 울산 태화강에서는 예전부터 바지락이 서식해 왔으며 인근 어민들의 전통적인 소득원으로서 주요 수산자원의 대상이 되어 왔다. 본 연구는 2009년 6월부터 2010년 6월까지 바지락의 현장조사를 통하여 자원생태학적 특성, 자원량 및 적정어획량 등의 자원평가를 실시하고 지속가능한 자원관리의 방안 제시 어업정책 수립을 위한 기초자료를 확보하고자 하였다. 태화강 수명은 6세로 추정되었고 von Bertalanffy growth function에 의하여 성장계수 K <TEX>$L_{\infty}$</TEX>은 0.341 46.64 cm로 구해졌다. Pauly 방법에 의한 순간전사망계수 (Z) 어획개시연령 (<TEX>$t_c$</TEX>) 1.171/년과 1.37년으로 구해졌고 현재의 순간어획사망계수는 0.626/년으로...