A5042683896- Retinal Diseases and Treatments
- Retinal Imaging and Analysis
- Glaucoma and retinal disorders
- Retinal and Macular Surgery
- Retinal and Optic Conditions
- Intraocular Surgery and Lenses
- Ocular Diseases and Behçet’s Syndrome
- Retinal Development and Disorders
- Corneal surgery and disorders
- Genetic factors in colorectal cancer
- Vascular Malformations Diagnosis and Treatment
- Genomics and Rare Diseases
- Retinopathy of Prematurity Studies
- Ophthalmology and Visual Impairment Studies
- Ocular Oncology and Treatments
- Ocular Infections and Treatments
- Acute Ischemic Stroke Management
- Optical Coherence Tomography Applications
- Diabetes Treatment and Management
- Cytomegalovirus and herpesvirus research
- Genomic variations and chromosomal abnormalities
- Ocular Disorders and Treatments
- Cardiovascular Health and Disease Prevention
- Neonatal Health and Biochemistry
- Ocular Surface and Contact Lens
Asan Medical Center
2014-2025
Ulsan College
2014-2025
University of Ulsan
2014-2025
Harvard University
2025
Smith-Kettlewell Eye Research Institute
2025
Massachusetts Eye and Ear Infirmary
2025
Hanyang University
2009-2013
Ophthalmology Associates (United States)
2012
Inje University
2012
Florida State University
2009-2010
To evaluate and compare the glaucoma discrimination ability of macular inner retinal layer (MIRL) thickness with that peripapillary nerve fiber (pRNFL) measured by spectral-domain optical coherence tomography (RTVue-100; Optovue Inc, Fremont, CA) in patients normal-tension (NTG).Sixty-five healthy subjects 102 NTG were enrolled. MIRL provided a ganglion cell complex (GCC) scan two RNFL thicknesses NHM4 (RNFL1) 3.45 (RNFL2) modes RTVue-100 system analyzed. The areas under receiver operating...
Abstract EVIDENCE, an automated variant prioritization system, has been developed to facilitate whole exome sequencing analyses. This study investigated the diagnostic yield of EVIDENCE in patients with suspected genetic disorders. DNA from 330 probands (age range, 0‐68 years) disorders were subjected sequencing. Candidate variants identified by and confirmed testing family members and/or clinical reassessments. reported a total 228 200 (60.6%) probands. The average number organs involved...
Purpose.: We evaluated the clinical use of segmented macular layer thickness measurement in terms glaucoma diagnosis and ability to detect progression, compare such outcomes those by circumpapillary retinal nerve fiber (cRNFLT) total (TMT) measurements. Methods.: The study included 141 glaucomatous 61 healthy eyes. All eyes were subjected at least four spectral domain optical coherence tomography (SD-OCT) examinations (mean follow-up, 2.13 years). Segmented layers (NFL), ganglion cell inner...
To investigate macular vascular integrity using optical coherence tomography angiography (OCTA) in patients undergoing vitrectomy for idiopathic epiretinal membrane (ERM) removal and to determine its association with structural visual outcomes.Forty-three unilateral ERM who were followed ≥6 months after surgery included. Ophthalmological evaluations included best-corrected acuity (BCVA) spectral-domain OCT (SD-OCT) before 6 surgery. We obtained en face OCTA images of the superficial...
To evaluate the characteristics of spectral-domain optical coherence tomography (SD-OCT) findings associated with visual outcome and compare OCT measurements according to presence cystoid macular edema (CME) in retinitis pigmentosa (RP) patients.Patients typical RP who underwent SD-OCT were included. We compared such as central retinal thickness (CRT), photoreceptor thickness, inner segment/outer segment (IS/OS) junctional status at fovea between CME non-CME groups. Also, correlations...
Aims To investigate the structural changes of superficial capillary plexuses (SCP) and deep (DCP) using optical coherence tomography (OCT) angiography (OCTA) in patients with idiopathic macular hole (MH) after surgery, determine factors related to evaluate its association postoperative visual outcomes. Methods Thirty-three unilateral MH who were followed for ≥6 months surgery included. Ophthalmologic evaluations included best corrected acuity (BCVA) spectral-domain OCT before 6 postsurgery....
Abstract Realistic image synthesis based on deep learning is an invaluable technique for developing high-performance computer aided diagnosis systems while protecting patient privacy. However, training a generative adversarial network (GAN) remains challenging because of the large amounts data required various kinds features. This study aims to synthesize retinal images indistinguishable from real and evaluate efficacy synthesized having specific disease augmenting class imbalanced datasets....
<h3>Aim:</h3> To identify optical coherence tomography (OCT) patterns predictive of visual outcome in diabetic macular oedema (DMO) patients who undergo focal laser photocoagulation. <h3>Methods:</h3> This study involved 70 eyes (45 patients) with clinically significant that underwent photocoagulation using the Early Treatment Diabetic Retinopathy Study protocol. Preoperative OCT images were retrospectively examined. features classified into four patterns: diffuse retinal thickening (DRT);...
We investigated whether serum vascular endothelial growth factor (VEGF) levels in acute-stage ischaemic stroke patients with small vessel disease (SVD) or large (LVD) are correlated long-term prognoses, based on the difference NIH Stroke Scale (NIHSS) scores between acute and chronic stages.From March 2007 to May 2008, we evaluated who experienced an for first time, defined as SVD (n = 89) LVD 91) using TOAST classification. Serum samples were taken immediately after admission (within 24 h...
To investigate the prevalence, characteristics, and visual acuity of spontaneous idiopathic epiretinal membrane (ERM) separations using spectral domain optical coherence tomography.In a series 1,248 consecutive eyes with ERM, Group I preexisting posterior vitreous detachment included 1,091 (87.4%) II without 157 (12.6%). Groups IA IIA self-resolution cases ERM from II, respectively.The self-separation occurred in 37 (3.0%) for 32.6 ± 11.7 months, 16 (1.5%) 21 (13.4%) IIA. The mean...
Myopia is the leading cause of vision impairment, affecting more than 1.4 billion people worldwide [1][2][3][4][5][6][7][8][9][10].Its prevalence has been increasing in Asia [1][2][3]5,7,[9][10][11][12][13][14].Myopia with a refractive error >-6 diopters (D) or an axial length >26 mm considered pathologic.It can lead to myopic retinopathy, characterized by lacquer crack formation, choroidal neovascularization, and chorioretinal atrophy [1-3, Purpose: To investigate macular microvasculature...
This retrospective study evaluated the real-world safety and effectiveness of switching to intravitreal brolucizumab for refractory neovascular age-related macular degeneration (nAMD). A total 81 patients who received injections as switch therapy were followed more than 3 months. good response was defined better anatomical improvement or extended injection intervals compared with previous anti-vascular endothelial growth factor (VEGF) treatment over a mean follow-up period 41.4 weeks....
The aim of this study was to evaluate the incidence and risk factors for development diabetic retinopathy (DR) progression proliferative DR (PDR) in Korean patients. Patients diagnosed with type 2 diabetes followed more than 5 years at a university-based clinic since 2000 were consecutively enrolled retrospective cohort study. Based on classification initial final visits, determined patient characteristics compared according progression. Hazard ratios each putative factor calculated...
Abstract To investigate angiographic characteristic features of diabetic choroidopathy, as well choroidal vascular density (CVD) and fractal dimension (CFD) in eyes controls using ultra-widefield (UWF) indocyanine green angiography (ICGA). All patients underwent UWF fluorescein ICGA. Using imageJ software, CVD CFD was analyzed. SFCT assessed spectral-domain optical coherence tomography. The image parameters were compared based on the DR stage presence macular edema (DME). One-hundred six...
Limited data are available regarding the long-term effects of pancreas transplantation on progression diabetic retinopathy (DR) and incidence associated risk factors for early worsening DR.Patients who underwent successful between January 2007 October 2015 were followed 1 year or longer consecutively enrolled. Variables demographic, systemic, metabolic, surgical reviewed each patient. DR was defined as (i) development aggravation macular edema requiring intravitreal anti-VEGF injections...
To evaluate the glaucoma progression in patients with a history of refractive corneal surgery (RCS).A total 313 eyes (RCS group, 34 eyes; non-RCS 279 eyes) mean follow-up period 2.7 years were included. Glaucoma was determined either by experts' stereoscopic optic disc/retinal nerve fiber layer (RNFL) photographs or serial visual field (VF) data. Uni- and multivariate Cox's proportional hazards models used to determine associations between potential risk factors including RCS...
We conducted targeted next-generation sequencing (TGS) and/or whole exome (WES) to assess the genetic profiles of clinically suspected retinitis pigmentosa (RP) in Korean population. A cohort 279 unrelated patients with diagnosed RP and available family members underwent molecular analyses using TGS consisting 88 RP-causing genes WES clinical variant interpretation. The combined tests (TGS WES) found a mutation 44 seven inherited retinal disease (IRD)-causing genes, total detection rate was...
A substantial proportion of patients with macula-off rhegmatogenous retinal detachment (RRD) experience poor visual recovery even after successful re-attachment surgery.Many studies have shown associations between structural changes and final outcomes in (RD) who undergone suc-cessful surgery.Preoperative acuity duration macular are known to influence post-surgery [1-3].More recent using optical coherence tomography (OCT) showed that preoperative OCT findings, such as a greater height the...