A5100345283- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Organ Donation and Transplantation
- Transplantation: Methods and Outcomes
- Renal and Vascular Pathologies
- Renal Diseases and Glomerulopathies
- Neurological Complications and Syndromes
- Liver Disease and Transplantation
- Cytomegalovirus and herpesvirus research
- Viral-associated cancers and disorders
- Polyomavirus and related diseases
- Diabetes Treatment and Management
- Organ and Tissue Transplantation Research
- Blood groups and transfusion
- Pancreatic function and diabetes
- Chronic Kidney Disease and Diabetes
- Complement system in diseases
- Hepatitis B Virus Studies
- SARS-CoV-2 and COVID-19 Research
- Potassium and Related Disorders
- Metabolism, Diabetes, and Cancer
- Pneumocystis jirovecii pneumonia detection and treatment
- Genetic Syndromes and Imprinting
- Immune Cell Function and Interaction
- Parvovirus B19 Infection Studies
Asan Medical Center
2016-2025
University of Ulsan
2016-2025
Ulsan College
2016-2025
Ministry of Food and Drug Safety
2024-2025
National Institute of Food and Drug Safety Evaluation
2024-2025
Seoul National University
2024
Park University
2022
Pancreas Centre (Canada)
2020-2021
Seoul National University Bundang Hospital
2017
Inje University Busan Paik Hospital
2012-2016
Abstract Accurate prediction of graft survival after kidney transplant is limited by the complexity and heterogeneity risk factors influencing allograft survival. In this study, we applied machine learning methods, in combination with statistics, to build new models that included immunological factors, as well known recipient donor variables. Graft was estimated from a retrospective analysis data multicenter cohort 3,117 recipients. We evaluated predictive power ensemble algorithms (survival...
Beneficial aspects of solid organ transplantation, which encompass survival benefit, improved quality life, and cost efficacy, have been clearly demonstrated. However, regional ethnic differences require further studies to identify prognostic factors transplant outcomes against various backgrounds. After previous efforts a nationwide, retrospective study on the kidney in Korea, new prospective-designed version Korean Organ Transplantation Registry (KOTRY) was launched 2014.Cohorts kidney,...
Kidney transplant (KT) is the optimal renal replacement therapy for patients with end-stage disease (ESRD). The demand kidneys, however, continues to exceed supply. To overcome this problem, efforts extend donor pool by including human leukocyte antigen (HLA)- and ABO-incompatible (ABOi) KTs are increasing. aim of article was retrospectively review data on recipients, profiles, clinical outcomes in 4000 cases KT. In addition, we analyzed ABOi flow-cytometric crossmatch (FCXM) positive KT a...
BACKGROUND Recent advances in desensitization techniques and immunosuppressive therapy have led to improved outcomes after ABO‐incompatible (ABO‐i) kidney transplantation (KT). However, questions remain unanswered, particularly regarding which type of ABO isoagglutinin—immunoglobulin M (IgM) or immunoglobulin (IgG)—is significantly involved antibody‐mediated rejection (AMR). STUDY DESIGN AND METHODS We retrospectively analyzed data from 120 patients who underwent ABO‐i KT between 2012 2014....
Bowel complications following kidney transplantation (KT) are rare but life-threatening, often necessitating bowel resection. These associated with immunosuppressive therapy, comorbidities, and viral infections. This study aimed to analyze the characteristics risk factors of patients who underwent resection after KT. A retrospective review was conducted 31 KT recipients between 1990 2020 at a single center. Patient data, including demographics, transplant-related factors, cytomegalovirus...
Abstract The Technological Change in Health Care Research Network collected unique patient‐level data on three procedures for treatment of heart attack patients (catheterization, coronary artery bypass grafts and percutaneous transluminal angioplasty) 17 countries over a 15‐year period to examine the impact economic institutional factors technology adoption. Specific are shown be important uptake these technologies. Health‐care systems characterized as public contract reimbursement have...
Limited data are available regarding the long-term effects of pancreas transplantation on progression diabetic retinopathy (DR) and incidence associated risk factors for early worsening DR.Patients who underwent successful between January 2007 October 2015 were followed 1 year or longer consecutively enrolled. Variables demographic, systemic, metabolic, surgical reviewed each patient. DR was defined as (i) development aggravation macular edema requiring intravitreal anti-VEGF injections...
Graft thrombosis immediately after surgery remains a problem for successful pancreas transplantation. The present study evaluated the efficacy of computed tomography (CT) angiography monitoring graft patency in immediate postoperative period.The involved 119 patients who underwent transplantation between July 1992 and December 2009 single center. anticoagulation strategy was heparin during then oral warfarin 1 to 6 months. monitored using color Doppler ultrasonography until 2005 (group A)...
Hepatic hemangioma represents the most common benign primary hepatic neoplasm. Although such tumors are small and asymptomatic, giant is frequently symptomatic, requires intervention. Moreover, diffuse multiple hemangiomatosis occupying almost entire liver extremely rare in adults, optimal management for this condition unclear. We report a case of rapidly growing, symptomatic with 50-year-old female patient who was treated by living-donor transplantation. This shows malignant behavior that...
Purpose Diabetic nephropathy is the leading cause of end stage renal disease. The number kidney transplantation (KT) due to diabetic increasing and there debate on glycemic control after KT. In this study, we used a multi-center database determine relationship between post-transplant outcomes KT in patients with nephropathy. Methods We conducted retrospective chart review transplant recipients (KTRs) from three tertiary hospitals analyze association clinical graft failure, including patient...
Asian patients undergoing kidney transplantation (KT) generally have better renal allograft survival and a lower burden of cardiovascular disease than those other racial groups. The KNOW-KT aims to explore rate, events, metabolic profiles elucidate the risk factors in Korean KT patients. is multicenter, observational cohort study encompassing 8 transplant centers Republic Korea. will enroll 1,000 recipients between 2012 2015 follow them up 9 years. At time at pre-specified intervals,...
With the recent update to Oxford classification for allograft IgA nephropathy (IgAN), additional investigations on clinical significance of updated components are warranted. We performed a retrospective cohort study at two tertiary hospitals. Kidney transplant recipients diagnosed with IgAN were included in after review by specialized pathologists. applied and determined MEST-C scores patients. The main outcome was death-censored graft failure within 10 years establishment diagnosis assessed...
Hyperparathyroidism is common in patients with chronic kidney disease reduced renal function and has been observed after transplantation. The optimal treatment for cases which hyperparathyroidism persists transplantation not determined.This retrospective study included 83 tertiary who underwent between 2000 2018 at a single center Korea. Sixty-four parathyroidectomy 19 were treated cinacalcet following Biochemical parameters clinical outcomes compared the two groups.Serum calcium parathyroid...
Abstract Background Recurrent focal segmental glomerulosclerosis (FSGS) after kidney transplantation (KT) is a serious complication and significant risk factor for graft failure. However, there no clear evidence of the effectiveness pre-transplant treatment using plasmapheresis (PP) or rituximab in preventing post-operative FSGS recurrence KT. Methods This single-center retrospective study included 99 adult patients with biopsy-proven primary who underwent KT between 2007 2018. The were...
<b><i>Background:</i></b> CD56+ and CD163+ cell infiltration in human kidney transplant biopsies have not been fully evaluated. <b><i>Methods:</i></b> We investigated the association of with antibody- or T-cell-mediated rejection (TCMR) other histologic lesions. One hundred seventy four clinically indicated were included this analysis. Immunohistochemical staining for C4d, CD56 CD163 was performed. <b><i>Results:</i></b>...
To evaluate retrospectively the clinical outcomes of living-donor kidney transplantations (LDKTs) using renal vein extension (RVE) for donor kidneys with short veins.Between January 2007 and December 2010, a total 576 LDKTs were performed grafts generated by hand-assisted laparoscopic nephrectomy: 31 (5.4%) transplants RVE 545 (94.6%) without an additional vascular procedure lengthening. Outcomes compared in patients who did not undergo during transplantation.The transplantation that...
Compared with the impact of delayed graft function (DGF) after renal transplantation, DGF pancreas transplantation has not been fully evaluated.We retrospectively verified on long-term survival in surgically successful cases. Pancreas failure was defined by recipient's return to exogenous insulin administration.Between May 2004 and April 2013, we performed 135 technically primary transplantations. Delayed as a total cumulative requirement 19 UI or greater within postoperative 7 days. Of...
<h3>Objective</h3> This study aimed to investigate the incidence and related clinical factors of LV hypertrophy (LVH) regression after kidney transplantation its effect on graft outcome. <h3>Methods</h3> Among 3373 transplant recipients who were enrolled in a multicentre cohort from 1997 2012, total 767 patients underwent echocardiography before included this followed for median 7.5 years. <h3>Results</h3> LVH steadily increased 7.4% at 1 year 35.4% 5 years over 5-year post-transplantation...
The Luminex test can detect low levels of donor-specific antibody (DSA) that cannot be detected by flow-cytometric cross-matching (FCXM) in kidney transplantation (KT). This study evaluated the impact DSA on clinical outcomes KT recipients negative FCXM. Of 575 consecutive patients who underwent living donor between January 2013 and July 2016, 494 (85.9%) were DSA-negative 81 (14.1%) DSA-positive. Although rates acute cellular rejection (ACR) at 1 year similar 2 groups (P = .54), incidence...
Background Population aging is a major health concern in Asian countries and it has affected the age distribution of patients with end-stage renal disease (ESRD). As consequence, need for kidney transplantation geriatric population increased, but shortage donors an obstacle transplantation. The aim this study was to evaluate risk factors graft failure death Methods Kidney transplantations performed tertiary hospital South Korea from May 1995 December 2014 were retrospectively reviewed....