A5000505018- Gastric Cancer Management and Outcomes
- Gastrointestinal Tumor Research and Treatment
- Endometrial and Cervical Cancer Treatments
- Neuroendocrine Tumor Research Advances
- Sarcoma Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Uterine Myomas and Treatments
- Colorectal Cancer Surgical Treatments
- Colorectal Cancer Treatments and Studies
- Pancreatic and Hepatic Oncology Research
- Gastrointestinal disorders and treatments
- HER2/EGFR in Cancer Research
- Histone Deacetylase Inhibitors Research
- Peptidase Inhibition and Analysis
- Genetic factors in colorectal cancer
- Thyroid Cancer Diagnosis and Treatment
- Cancer, Hypoxia, and Metabolism
- Metastasis and carcinoma case studies
- Colorectal and Anal Carcinomas
- Ferroptosis and cancer prognosis
- Hepatocellular Carcinoma Treatment and Prognosis
- Renal Diseases and Glomerulopathies
- Cancer Research and Treatments
- Prostate Cancer Diagnosis and Treatment
- Molecular Biology Techniques and Applications
Ulsan College
2015-2024
University of Ulsan
2015-2024
Asan Medical Center
2015-2024
Seoul Medical Center
2019
Gachon University
2018
Seoul Veterans Hospital
2012
MizMedi Hospital
2006-2008
Asan Foundation
2002
Purpose To (a) evaluate the postsurgical prognostic implication of Liver Imaging Reporting and Data System (LI-RADS) categories primary liver cancers (b) determine performance LI-RADS version 2017 in differentiating hepatocellular carcinoma (HCC) from intrahepatic cholangiocarcinoma (IHCC) combined hepatocellular-cholangiocarcinoma (cHCC-CC) at gadoxetic acid-enhanced MRI. Materials Methods In this retrospective study, 194 patients with cirrhosis surgically proven single cancer (53 cHCC-CC,...
Purpose To evaluate gadoxetic acid-enhanced magnetic resonance imaging (MRI) findings of combined hepatocellular cholangiocarcinoma (cHCC-CC) with special emphasis on correlation MRI histopathologic tumor characteristics and survival outcomes after curative surgery. Materials Methods Our Institutional Review Board approved this study, a waiver informed consent. For 82 patients (64 men, 18 women; mean age, 54.0 years; age range, 30–81) surgically confirmed cHCC-CCs, we evaluated clinical...
The present study aimed to identify molecules associated with lymphovascular invasion (LVI) and perineural (PNI) examine their biological behavior in colorectal cancer (CRC). LVI- PNI-associated were identified verified using sequential processes including (1) identification of 117 recurrence-associated genes differentially expressed on RNA-seq analysis primary tissues from 130 CRC patients without systemic recurrence; (2) LVI PNI; (3) assessment properties by measuring proliferation,...
Goals: The aim of this study was to evaluate the adequacy and diagnostic yield histologic core obtained with a 22 G endoscopic ultrasound histology needle using capillary sampling stylet slow-pull technique without on-site cytopathologist. Background: No standard for new EUS has been established. Study: A total 125 consecutive patients intra-abdominal solid masses were enrolled prospectively between October 2011 March 2013. EUS-guided fine biopsy (EUS-FNB) performed. Results: 133 EUS-FNB...
According to the 2010 World Health Organization classification, all gastrointestinal neuroendocrine tumors (NETs) are classified as malignant except for L-cell-type (glucagon-like peptide [GLP] and YY [PYY]-producing) NETs. However, L-cell immunophenotype in rectal NETs has not been widely studied previously. Immunohistochemical labeling of markers with GLP1 PYY was performed 208 surgically or endoscopically resected NET cases tissue microarrays compared clinicopathologic features patient...
This study analyzed the expression of CD44 and cystine-glutamate transporter SLC7A11 (xCT) in primary oral cavity squamous cell carcinoma (SCC) relationships to tumor recurrence patient survival.Associations between xCT clinicopathologic results were 231 patients with SCC. Cox proportional hazard analyses used identify factors associated recurrence-free survival (RFS), disease-specific (DSS), overall (OS).Overexpression and/or was advanced T classification, perineural invasion,...
ABSTRACT Objectives: The aim of the study was to correlate liver stiffness (LS) and hepatic venous‐pressure gradient (HVPG) evaluate diagnostic performance shear‐wave elastography (SWE) for predicting clinically significant portal hypertension in children with suspected diseases, consideration reliability criteria. Methods: We identified 33 SWEs from 32 who underwent HVPG measurement within 2 weeks between June 2012 October 2015. correlation LS assessed. (HVPG ≥ 10 mmHg) assessed using...
Metallothionein (MT)-1 and -2 are low-molecular weight, cysteine-rich, intracellular metal-binding proteins involved in diverse functions, such as metal homeostasis, cell cycle progression, differentiation, carcinogenesis. This study investigated the expression of MT-1 MT-2 a prognostic marker hepatocellular carcinoma (HCC).Expression were evaluated immunohistochemically tissue microarrays containing samples from 370 HCCs, 336 adjacent noncancerous livers, 12 normal livers. The relationships...
In 2010, the World Health Organization categorized L-cell type neuroendocrine tumors (NETs) as of uncertain malignancy, while all others were classified malignant. However, diagnostic necessity immunophenotyping is unclear, are tumor stage and grade that may guide diagnosis management. To clarify predictive markers rectal neoplasms (NENs), 5- 10-year overall survival (OS) was analyzed by pathological parameters including phenotype.A total 2,385 NENs from our previous multicenter study a...
We explored system <math xmlns="http://www.w3.org/1998/Math/MathML" id="m1" overflow="scroll"><mrow><msubsup><mi mathvariant="normal">x</mi><mi mathvariant="normal">C</mi><mo>−</mo></msubsup></mrow></math> transporter activity and the detection of inflammatory or infectious lesions using (4<i>S</i>)-4-(3-<sup>18</sup>F-fluoropropyl)-l-glutamate (<sup>18</sup>F-FSPG) PET. <b>Methods:</b> In 10 patients with various diseases, as many 5 largest were selected reference lesions....
The prognosis of advanced biliary tract cancer (BTC) is poor with the standard gemcitabine and cisplatin (GemCis) regimen. Given that rates human epidermal growth factor receptor 2 (HER2) positivity in BTC reaches around 15%, HER2-targeted therapy needs further investigation. This study aims to evaluate preliminary efficacy/safety first-line trastuzumab-pkrb plus GemCis patients BTC. Patients unresectable/metastatic HER2-positive received (on day 1 each cycle, 8 mg/kg for first cycle 6...
Cancer diagnosis is associated with an increased suicide risk, particularly within the first 1 year after of cancer. Abnormal function hypothalamic-pituitary-adrenal axis has been implicated in pathophysiology depression and suicide. We examined genetic associations functional Bcl-1 polymorphism (rs41423247) neuron-specific glucocorticoid receptor (NR3C1) gene, death by cancer patients. Suicides occurring a ('early suicide') were considered separately from those suicides during second or...
<b><i>Background:</i></b> CD56+ and CD163+ cell infiltration in human kidney transplant biopsies have not been fully evaluated. <b><i>Methods:</i></b> We investigated the association of with antibody- or T-cell-mediated rejection (TCMR) other histologic lesions. One hundred seventy four clinically indicated were included this analysis. Immunohistochemical staining for C4d, CD56 CD163 was performed. <b><i>Results:</i></b>...
This article has been corrected. See ERRATUM: Prognostic Implications of Extranodal Extension in Relation to Colorectal Cancer Location.