A5085965565- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Venous Thromboembolism Diagnosis and Management
- Stroke Rehabilitation and Recovery
- Intracranial Aneurysms: Treatment and Complications
- Atrial Fibrillation Management and Outcomes
- Traumatic Brain Injury and Neurovascular Disturbances
- Long-Term Effects of COVID-19
- Cardiovascular Health and Disease Prevention
- COVID-19 and healthcare impacts
- Lipoproteins and Cardiovascular Health
- Inflammatory Biomarkers in Disease Prognosis
- Liver Disease and Transplantation
- Health and Wellbeing Research
- Cardiac tumors and thrombi
- Neurological and metabolic disorders
- Peripheral Artery Disease Management
- Liver Disease Diagnosis and Treatment
- Eosinophilic Disorders and Syndromes
- Retinal and Optic Conditions
- Vasculitis and related conditions
- Advanced X-ray and CT Imaging
- COVID-19 Clinical Research Studies
- Diverse Approaches in Healthcare and Education Studies
- Infective Endocarditis Diagnosis and Management
Keimyung University
2019-2025
Keimyung University Dongsan Medical Center
2020-2024
Yonsei University
2017-2024
Severance Hospital
2018-2024
United Nations Economic and Social Commission for Asia and the Pacific
2021-2024
Hallym University
2024
Sungkyunkwan University
2024
Wonju Severance Christian Hospital
2024
Gangnam Severance Hospital
2024
Wonkwang University
2011-2023
Background and Purpose- The prediction of long-term outcomes in ischemic stroke patients may be useful treatment decisions. Machine learning techniques are being increasingly adapted for use the medical field because their high accuracy. This study investigated applicability machine to predict patients. Methods- was a retrospective using prospective cohort that enrolled with acute stroke. Favorable outcome defined as modified Rankin Scale score 0, 1, or 2 at 3 months. We developed models...
Importance Optimal blood pressure (BP) control after successful reperfusion with endovascular thrombectomy (EVT) for patients acute ischemic stroke is unclear. Objective To determine whether intensive BP management during the first 24 hours leads to better clinical outcomes than conventional in who underwent EVT. Design, Setting, and Participants Multicenter, randomized, open-label trial a blinded end-point evaluation, conducted across 19 centers South Korea from June 2020 November 2022...
Shin H-R (Department of Preventive Medicine, College Dong-A University, #1 3Ga Dangdaeshin-dong, So-gu Pusan, Korea 602-103), Lee C-U, Park H-J, Seol S-Y, Chung J-M, Chol H-C, Y-O and Shigemaslu T. International Journal Epidemiology 1996; 25: 933–940. Liver cancer mortality in is the highest world. Hepatitis B C viruses (HBV, HCV) are known to be major risk factors hepatocellular carcinoma (HCC). Cholangiocarcinoma (CLG) accounts for more than 20% liver Pusan area. In Korea, diferent roles...
Background and Purpose— Stent retriever (SR) thrombectomy has become the mainstay of treatment acute intracranial large artery occlusion. However, it is still not much known about optimal limit SR attempts for favorable outcome. We evaluated whether a specific number passes futile recanalization can be determined. Methods— Patients who were treated with as first endovascular modality their occlusion in anterior circulation retrospectively reviewed. The rate each pass was calculated....
Background Acute stroke because of basilar artery occlusion (BAO) represents 1% all ischemic strokes. However, recanalization rates and treatment outcome for the different pathologic subtypes BAO are not fully understood. Purpose To compare rate clinical outcomes mechanical thrombectomy in BAO. Materials Methods Eighty-two patients (46 men 36 women; mean age, 73 years; age range, 20–90 men, 70 years [age years]; women, 75 range; 61–90 years]) with acute who underwent between March 2010...
The histological features of thrombus in stroke patients with cancer are not well known. Using immunohistochemical staining thrombi retrieved during mechanical thrombectomy patients, compositions were compared between 16 active cancer, inactive and without any history cancer. group showed higher platelet lower erythrocyte fractions than the or control group. Four vegetation very high low fractions. Patients cryptogenic etiology a similar pattern to those vegetation. These findings may aid...
Sarcopenia, a age-related disease characterized by loss of muscle mass accompanied function, is associated with nutrition imbalance, physical inactivity, insulin resistance, inflammation, metabolic syndrome, and atherosclerosis which are risk factors for cardiovascular disease. However, its association outcomes after ischemic stroke has not been well-established. This study investigated whether functional patients acute sarcopenia.Data were collected from 568 consecutive National Institute...
The effects of blood pressure (BP) lowering in patients treated with intravenous tissue plasminogen activator (IV tPA) before endovascular thrombectomy (EVT) are unclear. This study aims to investigate whether intensive and conventional BP management affect outcomes differently, depending on IV tPA administration EVT. In this subgroup analysis the Outcome Patients Treated Intra-Arterial Thrombectomy-Optimal Blood Pressure Control (OPTIMAL-BP; ClinicalTrials.gov Identifier: NCT04205305)...
Background: Previous risk assessment tools for patients with atrial fibrillation (AF) have not primarily focused on those acute ischemic stroke (AIS). Prediction models that rely solely clinical parameters shown limited predictive ability, underscoring the need incorporate neuroimaging to improve prediction of recurrence in AIS AF. Method: The East-Asian Ischemic Stroke Patients Atrial Fibrillation (EAST-AF) study was a nationwide, multicenter prospective registry enrolled AF from 15...
BACKGROUND The link between arterial stiffness, measured by estimated pulse wave velocity (ePWV), and outcomes following endovascular thrombectomy (EVT) has not been tested. This study aimed to determine whether ePWV predicts post‐EVT outcome in patients with acute ischemic stroke. METHODS was a secondary analysis of the OPTIMAL‐BP (Outcome Patients Treated With Intraarterial Thrombectomy–Optimal Blood Pressure Control) trial, which enrolled 302 EVT from 19 stroke centers South Korea June...
Background and Purpose- We investigated whether measuring the volume density of a thrombus could predict nonrecanalization after intravenous thrombolysis. Methods- This study included retrospective cohort to develop computed tomography marker for predicting thrombolysis prospective multicenter validation this marker. The were measured semiautomatically using 3-dimensional software on baseline thin-section noncontrast (1 or 1.25 mm). Recanalization was assessed angiography magnetic resonance...
<b><i>Background:</i></b> To investigate whether there are differences in long-term all-cause and cardiovascular mortality according to the burden of liver fibrosis or steatosis patients with ischaemic stroke transient attack (TIA). <b><i>Methods:</i></b> Consecutive acute TIA who underwent elastography (TE) from January 2014 December were considered eligible. The influence steatosis, assessed via TE, on outcomes was investigated using Cox...
Patients with acute stroke are often accompanied by comorbidities, such as active cancer. However, adequate treatment guidelines not available for these patients. The purpose of this study was to evaluate the association between cancer and outcomes reperfusion therapy in patients stroke.We compared who underwent therapy, using a nationwide registry. We divided into 3 groups according activity: cancer, nonactive without history investigated processes, 24-hour neurological improvement, adverse...
Importance The associations between blood pressure (BP) decreases induced by medication and functional outcomes in patients with successful endovascular thrombectomy remain uncertain. Objective To evaluate whether BP reductions intravenous medications are associated poor at 3 months. Design, Setting, Participants This cohort study was a post hoc analysis of the Outcome Patients Treated With Intra-Arterial Thrombectomy–Optimal Blood Pressure Control trial, comparison intensive conventional...
Abstract The prognosis of patients with embolic stroke undetermined source (ESUS) may vary according to the underlying cause. Therefore, we aimed divide ESUS into subtypes and assess long-term outcomes. Consecutive acute ischemic who underwent a comprehensive workup, including transesophageal echocardiography prolonged electrocardiography monitoring, were enrolled. We classified minor cardioembolic (CE) ESUS, arteriogenic two or more causes no cause ESUS. Arteriogenic was sub-classified...
<b><i>Introduction:</i></b> There are a limited number of studies investigating the relationship between degree liver fibrosis and long-term prognosis, especially ischemic stroke (IS) recurrence, in first-ever IS or transient attack (TIA). <b><i>Objective:</i></b> We investigated whether there differences all-cause cardiovascular mortalities recurrence based on TIA. <b><i>Methods:</i></b> This analysis included 2,504...
The safety and efficacy of tirofiban during endovascular therapy in patients undergoing intravenous thrombolysis with recombinant IV tPA remain unclear. This study aimed to investigate the intra-arterial use treated tPA.Using a multicenter registry, we enrolled acute ischemic stroke who underwent therapy. Safety outcomes included postprocedural parenchymal hematoma type 2 and/or thick subarachnoid hemorrhage, intraventricular 3-month mortality. Efficacy successful reperfusion rate,...
We aimed to develop and validate machine learning models diagnose patients with ischemic stroke cancer through the analysis of histopathologic images thrombi obtained during endovascular thrombectomy.This was a retrospective study using prospective multicenter registry which enrolled consecutive acute from South Korea who underwent thrombectomy. This included admitted between July 1, 2017 December 31, 2021 6 academic university hospitals. Whole-slide scanning performed for...
Background and Purpose Nonbacterial thrombotic endocarditis (NBTE) is a cause of stroke in cancer. However, clinical characteristics outcomes patients with cancer-associated NBTE are not well known.<br/>Methods We included consecutive active cancer over 9-year period who underwent echocardiography. retrospectively compared presence metastasis between NBTE, those cryptogenic etiologies, determined etiologies. also investigated mortality events during the 6-month...
There is much uncertainty in endovascular treatment (EVT) decisions patients with acute large vessel occlusion (LVO) and mild neurological deficits.