A5100657608- Acute Ischemic Stroke Management
- Cerebrovascular and Carotid Artery Diseases
- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced MRI Techniques and Applications
- Stroke Rehabilitation and Recovery
- Venous Thromboembolism Diagnosis and Management
- Asymmetric Hydrogenation and Catalysis
- Cardiac Valve Diseases and Treatments
- Asymmetric Synthesis and Catalysis
- Fatigue and fracture mechanics
- Vascular Malformations Diagnosis and Treatment
- Gastric Cancer Management and Outcomes
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Advanced Neuroimaging Techniques and Applications
- Glioma Diagnosis and Treatment
- Vestibular and auditory disorders
- Cardiac, Anesthesia and Surgical Outcomes
- Cerebrospinal fluid and hydrocephalus
- Cancer Treatment and Pharmacology
- Atrial Fibrillation Management and Outcomes
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Colorectal Cancer Treatments and Studies
- Anesthesia and Sedative Agents
Korea University
2013-2025
Seoul National University
2023-2025
Samsung Medical Center
2012-2024
Sungkyunkwan University
2012-2024
Korea University Medical Center
2015-2024
Yonsei University
2018-2024
Palmetto Hematology Oncology
2021
Yeungnam University
2014-2020
Yeungnam University College
2020
Severance Hospital
2018
Background and Purpose— Effective rescue treatment has not yet been suggested in patients with mechanical thrombectomy (MT) failure. This study aimed to test whether stenting (RS) improved clinical outcomes MT-failed patients. Methods— is a retrospective analysis of the cohorts 16 comprehensive stroke centers between September 2010 December 2015. We identified who underwent MT but failed recanalize intracranial internal carotid artery or middle cerebral M1 occlusion. Patients were...
The multiparametric imaging can show us different aspects of tumor behavior and may help differentiation recurrence from treatment related change. Our aim was to differentiate progression pseudoprogression in patients with glioblastoma by using histogram analysis 2 consecutive MR studies relative cerebral blood volume ADC values.Thirty-five new or increased size enhancing lesions after concomitant chemoradiation therapy following surgical resection were included. Combined histograms made the...
We report here a stereodivergent method for the Michael addition of aryl acetic acid esters to α,β-unsaturated aldehydes catalyzed by combination chiral pyrrolidine and Lewis base. This reaction proceeds through synergistic catalytic cycle which consists one leading iminium electrophile second generating nucleophilic enolate construction carbon–carbon bond. By varying combinations catalyst enantiomers, all four stereoisomers products with two vicinal stereocenters are accessible high...
Background and Purpose— Stent retriever (SR) thrombectomy has become the mainstay of treatment acute intracranial large artery occlusion. However, it is still not much known about optimal limit SR attempts for favorable outcome. We evaluated whether a specific number passes futile recanalization can be determined. Methods— Patients who were treated with as first endovascular modality their occlusion in anterior circulation retrospectively reviewed. The rate each pass was calculated....
Background: It is unknown whether the direct oral anticoagulant edoxaban can reduce leaflet thrombosis and accompanying cerebral thromboembolic risk after transcatheter aortic valve replacement. In addition, causal relationship of subclinical with thromboembolism neurological or neurocognitive dysfunction remains unclear. Methods: We conducted a multicenter, open-label randomized trial comparing dual antiplatelet therapy (aspirin plus clopidogrel) in patients who had undergone successful...
Background and Purpose— Based on its mechanism, the use of balloon guide catheters (BGCs) may be beneficial during endovascular treatment, regardless type mechanical recanalization modality used—stent retriever thrombectomy or thrombaspiration. We evaluated whether BGCs can first-line used. Methods— retrospectively reviewed consecutive acute stroke patients who underwent stent thrombaspiration from prospectively maintained registries 17 centers nationwide. Patients were assigned to BGC...
Abstract Objective Conventionally, MRI aids in differentiating acute unilateral peripheral vestibulopathy/vestibular neuritis (AUPV/VN) from mimickers. Meanwhile, the diagnostic utility of MRIs dedicated to inner ear remains be elucidated for diagnosing AUPV/VN. Methods We prospectively recruited 53 patients with AUPV/VN (mean age ± SD = 60 15 years, 29 men). Initial were performed a standard protocol, and an additional axial 3D‐fluid‐attenuated inversion recovery (3D‐FLAIR) sequence was...
Antiplatelet resistance is known to be associated with symptomatic ischemic complication after endovascular coil embolization. The purpose of our study was evaluate the relationship between antiplatelet and clinically silent thromboembolic complications using DWI in patients who underwent embolization for unruptured intracranial aneurysm.Between October 2011 May 2013, 58 62 aneurysms were measured response VerifyNow assay elective an aneurysm posttreatment enrolled. Diffusion-positive...
Background/Objectives: The cavernous sinus air sign, historically linked to trauma or venous thrombosis, has recently been reported in association with retrograde embolism, often without clinical significance. Despite this, its exact prevalence, etiology, and relevance remain unclear. This study aims systematically evaluate the incidence of sign patients undergoing CT angiography (CTA) assess potential implications. Methods: We retrospectively analyzed data from who underwent CTA between...
Background Mechanical thrombectomy (MT) is a primary endovascular modality for acute intracranial large vessel occlusion. However, further treatment, such as rescue stenting, occasionally necessary refractory cases. We aimed to investigate the efficacy and safety of stenting in first-line MT failure identify clinical factors affecting its outcome. Methods A multicenter prospective registry was designed this study. enrolled consecutive patients who underwent failure. Endovascular details...
Developmental venous anomalies are the most common intracranial vascular malformation. Increased signal-intensity on T2-FLAIR images in areas drained by developmental encountered occasionally brain imaging studies. We evaluated diffusion and perfusion MR findings of abnormally high signal intensity associated with to describe their pathophysiologic nature.We retrospectively reviewed 34 subjects abnormalities anomalies. All underwent contrast imaging. Regions interest were placed covering...
Anecdotal studies have reported the presence of antiganglioside antibodies in acute unilateral peripheral vestibulopathy (AUPV). This study aimed to determine prevalence, clinical characteristics, and neurotologic findings AUPV associated with antibodies.
Abstract Background To determine the usefulness of dual‐energy CT (DECT) iodine quantification to classify focal thyroid lesions. Methods We retrospectively enrolled a total 76 cytopathologically confirmed lesions (mean size: 1.9 cm). After drawing region interest on DECT‐derived maps, obtained concentration values nodules (IC_N) and normalized IC_N were compared between 3 groups: papillary carcinoma (PTC), benign nodule, cyst. Results From all lesions, 46, 17, 13 assigned PTC, cyst groups....
Background and Purpose- Perfusion-based triage has proven to be effective safe for selecting patients who are likely benefit from endovascular thrombectomy (EVT) in a late time window. We investigated collateral-based EVT presenting beyond 6 hours, terms of interrater reliability efficacy predicting clinical outcome, comparison perfusion-based triage. Methods- One hundred thirty-two underwent both computed tomographic angiography tomography perfusion anterior circulation large artery...
Abstract BACKGROUND It remains controversial whether carotid artery stenting (CAS) is needed in cases of tandem cervical internal occlusion (cICAO) and intracranial large vessel (LVO). OBJECTIVE To investigate the efficacy safety CAS combination with endovascular thrombectomy (CAS-EVT) cICAO-LVO patients to compare its outcomes those EVT without (EVT-alone). METHODS We identified all who underwent for from prospectively maintained registries 17 stroke centers. Patients were classified into 2...
Endovascular coil embolization for ophthalmic artery (OphA) aneurysms has the latent risk of occlusion OphA during procedure, which can lead to loss vision. We report clinical and angiographic results endovascular treatment together with efficacy balloon test (BOT).From August 2005 December 2013, 31 consecutive patients 33 were treated in our institution. The classified into two groups according location within aneurysmal sac. BOT was performed 28 using a hypercompliant before coiling....
Backgroud The need for rescue treatment (RT) may differ depending on first-line modality (stent retriever (SR) or contact aspiration (CA)) in endovascular thrombectomy (EVT). We aimed to investigate whether the type of EVT was associated with RT. Methods identified all patients who underwent anterior circulation large-vessel occlusion from prospectively maintained registries 17 stroke centers. Patients were dichotomized into SR-first and CA-first. RT involved switching other device, balloon...
Abstract BACKGROUND The optimal magnetic resonance angiography (MRA) sequence for assessing the aneurysm occlusion state or in-stent flow after endovascular coiling is not well established. OBJECTIVE To evaluate diagnostic performance of pointwise encoding time reduction with radial acquisition (PETRA)-MRA in patients who underwent relative to that time-of-flight (TOF)-MRA and contrast-enhanced (CE)-MRA. METHODS We evaluated using digital subtraction (DSA) MRA. In stent-assisted coiling, we...
4026 Background: We report the second interim analysis of START. Methods: START is a phase II, multicenter, open-label, single-arm study being conducted in Asia Pacific. Patients with unresectable, intermediate-stage HCC (BCLC B), and who are candidates for TACE eligible. receive lipiodol doxorubicin (30-60 mg), followed by embolization absorbable particles. Sorafenib 400mg bid given continuously, dose interruptions 4 days before after TACE, which performed every 6-8 weeks. Tumor response...