Jae-Kwan Cha
- Antiplatelet Therapy and Cardiovascular Diseases
- Intracranial Aneurysms: Treatment and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Parkinson's Disease Mechanisms and Treatments
- Neurological Disease Mechanisms and Treatments
- Neurosurgical Procedures and Complications
- Sleep and Wakefulness Research
- Restless Legs Syndrome Research
Dong-A University Hospital
2015-2025
Stent-assisted coiling of intracranial aneurysms requires antiplatelet therapy, typically aspirin and clopidogrel to prevent thromboembolic complications. There is a substantial concern that tirofiban may increase the risk hemorrhage when used as an premedication in ruptured aneurysms. Our aim was evaluate safety efficacy intravenous administration, instead oral dual agents, for stent-assisted patients with acutely aneurysms.We conducted retrospective review data base containing consecutive...
Previous research on patients with acute ischemic stroke (AIS) has shown a 0.5% incidence of major gastrointestinal bleeding (GIB) requiring blood transfusion during hospitalization. The existing literature insufficiently explored the long-term in this population despite decremental impact GIB outcomes. We analyzed data from cohort AIS admitted to 14 hospitals as part nationwide multicenter prospective registry between 2011 and 2013. These were followed up for 6 years. occurrence events,...
Antiplatelet resistance is known to be associated with symptomatic ischemic complication after endovascular coil embolization. The purpose of our study was evaluate the relationship between antiplatelet and clinically silent thromboembolic complications using DWI in patients who underwent embolization for unruptured intracranial aneurysm.Between October 2011 May 2013, 58 62 aneurysms were measured response VerifyNow assay elective an aneurysm posttreatment enrolled. Diffusion-positive...
Exercise enhances cognitive function and increases the size of hippocampus in ischemic stroke patients. Medial septal neurons are sources cholinergic GABAergic afferents to involve upregulation brain derived neurotrophic factor response exercise. Oxiracetam activates acetylcholine utilization hippocampus. Various clinical trials showed that its effect was modest patients with vascular impairment. This study aims investigate on impairment after explore whether this is modified by The OVeRCOME...