Jun Yup Kim

ORCID: 0000-0003-4764-5714
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About
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Research Areas
  • Acute Ischemic Stroke Management
  • Cerebrovascular and Carotid Artery Diseases
  • Stroke Rehabilitation and Recovery
  • Venous Thromboembolism Diagnosis and Management
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Advanced Nanomaterials in Catalysis
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Atrial Fibrillation Management and Outcomes
  • Neurological Disease Mechanisms and Treatments
  • Lipoproteins and Cardiovascular Health
  • Neurological Disorders and Treatments
  • Antiplatelet Therapy and Cardiovascular Diseases
  • Nanocluster Synthesis and Applications
  • Retinal and Optic Conditions
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Cardiovascular Health and Risk Factors
  • Dementia and Cognitive Impairment Research
  • Vestibular and auditory disorders
  • Cardiovascular and Diving-Related Complications
  • Cardiovascular Disease and Adiposity
  • Retinal Imaging and Analysis
  • Cerebral Venous Sinus Thrombosis
  • Intracranial Aneurysms: Treatment and Complications
  • Moyamoya disease diagnosis and treatment

Seoul National University Bundang Hospital
2016-2025

Hanyang University Medical Center
2025

Incheon Medical Center
2024

Seoul National University Hospital
2012-2023

Seoul National University
2012-2022

New Generation University College
2020-2021

National University College
2020-2021

Asan Medical Center
2020

Chonnam National University Hospital
2020

Korea University
2020

Uniform 3 nm-sized ceria nanoparticles can protect against ischemic stroke by scavenging reactive oxygen species (ROS) and reducing apoptosis. PEGylated showed protective effects ROS-induced cell death in vitro. Optimal doses of reduced infarct volumes the rate vivo. Detailed facts importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset. They made available submitted authors. Please note: The publisher is...

10.1002/anie.201203780 article EN Angewandte Chemie International Edition 2012-09-11

Despite the great socioeconomic burden of stroke, there have been few reports stroke statistics in Korea. In this scenario, Epidemiologic Research Council Korean Stroke Society launched "Stroke Statistics Korea" project, aimed at writing a contemporary, comprehensive, and representative report on epidemiology This contains general prevalence behavioral vascular risk factors, characteristics, pre-hospital system care, hospital management, quality outcomes. report, we analyzed most up-to-date...

10.5853/jos.2018.03125 article EN cc-by-nc Journal of Stroke 2018-12-18

<h3>Importance</h3> Endovascular treatment (EVT) after ischemic stroke due to emergent large vessel occlusion is usually constrained by a specific window of less than 16 24 hours from the time patient was last known well (LKW). Patients with slow progression and tenacious collateral circulation may persist beyond hours. <h3>Objectives</h3> To estimate prevalence salvageable tissues or more LKW investigate effectiveness EVT in delayed occlusion. <h3>Design, Setting Participants</h3> In this...

10.1001/jamaneurol.2020.2804 article EN JAMA Neurology 2020-08-10

Einheitliche 3 nm große Cerdioxidnanopartikel können vor ischämischen Hirninfarkten schützen, indem sie reaktive Sauerstoffspezies (ROS) abfangen und die Apoptose zurückdrängen. PEGylierte waren in vitro gegen ROS-induzierten Zelltod wirksam. Optimale Dosen solcher Nanopartikel verringerten das Infarktvolumen verlangsamten den Zelltod. Detailed facts of importance to specialist readers are published as "Supporting Information". Such documents peer-reviewed, but not copy-edited or typeset....

10.1002/ange.201203780 article EN Angewandte Chemie 2012-09-11

Cochlear implantation (CI) is a highly effective treatment for profound hearing loss in elderly individuals, including those with ARHL. However, factors influencing the success of CI population are not fully understood. Hence, we sought to investigate association regional cerebellar gray matter volume effectiveness elderly. This retrospective cross-sectional study included implantees and healthy controls aged ≥ 70 years. We used voxel-based morphometry associated speech perception outcome...

10.1038/s41598-024-78322-5 article EN cc-by-nc-nd Scientific Reports 2025-01-24

Introduction: The human microbiome has been studied in various diseases, including inflammatory bowel disease, diabetes, obesity, and cardiovascular diseases. However, its role acute ischemic stroke (AIS) remains underexplored. This study aims to investigate the profiles stool saliva samples from AIS patients compared control groups identify distinct microbial patterns associated with stroke. Methods: We enrolled 54 patients, collecting within one week of admission. Saliva was either...

10.1161/str.56.suppl_1.wp374 article EN Stroke 2025-01-30

Previous research on patients with acute ischemic stroke (AIS) has shown a 0.5% incidence of major gastrointestinal bleeding (GIB) requiring blood transfusion during hospitalization. The existing literature insufficiently explored the long-term in this population despite decremental impact GIB outcomes. We analyzed data from cohort AIS admitted to 14 hospitals as part nationwide multicenter prospective registry between 2011 and 2013. These were followed up for 6 years. occurrence events,...

10.5853/jos.2024.00661 article EN cc-by-nc Journal of Stroke 2025-01-31

Abstract The limited accessibility of medical specialists for Alzheimer’s disease (AD) can make obtaining an accurate diagnosis in a timely manner challenging and may influence prognosis. We investigated whether VUNO Med-DeepBrain AD (DBAD) using deep learning algorithm be employed as decision support service the AD. This study included 98 elderly participants aged 60 years or older who visited Seoul Asan Medical Center Korea Veterans Health Service. administered standard diagnostic...

10.1038/s41598-022-22917-3 article EN cc-by Scientific Reports 2022-10-26

<h3>Objective</h3> Stroke is a devastating and costly disease; however, there paucity of information on long-term costs how they differ according to 3-month modified Rankin scale (mRS) score, which primary outcome variable in acute stroke intervention trials. <h3>Methods</h3> We analyzed prospective multicenter registry (Clinical Research Collaboration for Korea) database through linkage with claims data from the National Health Insurance Service follow-up December 2016. Healthcare...

10.1212/wnl.0000000000009034 article EN Neurology 2020-02-07

Treatments for breast cancer often include interventions related to psychosocial issues such as negative body image, loss of femininity, and low self-esteem. We identified the psychological effects a cosmetics education programme in patients with cancer. Cosmetic is specific care designed help handle appearance-related side effects. Thirty-one women at university hospital South Korea who received were compared 29 subjects control group treatment usual. Psychological factors including...

10.1111/ecc.12290 article EN European Journal of Cancer Care 2015-02-04

Background: This study aimed to describe the current status of acute stroke care in Korea and explore disparities among hospitals regions.Methods: The 2013 2014 national audit data health insurance claims were linked used for this study.Stroke patients hospitalized via emergency rooms within 7 days onset selected.Results: A total 19,608 treated 216 analyzed.Among them 76% had ischemic stroke; 15%, intracerebral hemorrhage (ICH); 9%, subarachnoid (SAH).Of hospitals, 31% provided inpatient...

10.3346/jkms.2020.35.e167 article EN cc-by-nc Journal of Korean Medical Science 2020-01-01

Background The optimal first-line mechanical thrombectomy (MT) method in cancer-related stroke (CRS) patients with emergent large vessel occlusion (ELVO) remains largely unknown. aim of this study is to evaluate the efficacy and safety between contact aspiration (CA) stent retriever (SR) CRS patients. Methods Sixty-two ELVO, who underwent MT January 2013 October 2019 at our institution, were retrospectively analyzed. Patients divided into two groups based on compared: CA group (n=28), which...

10.1136/neurintsurg-2020-016144 article EN Journal of NeuroInterventional Surgery 2020-06-25

Background The long-term incidence of acute myocardial infarction (AMI) in patients with ischemic stroke (AIS) has not been well defined large cohort studies various race-ethnic groups. Methods and Results A prospective AIS who were registered a multicenter nationwide registry (CRCS-K [Clinical Research Collaboration for Stroke Korea] registry) was followed up the occurrence AMI through linkage National Health Insurance Service claims database. 5-year cumulative annual risk estimated...

10.1161/jaha.120.018807 article EN cc-by-nc-nd Journal of the American Heart Association 2020-12-29

Background and Purpose: Intracranial atherosclerosis-related large-vessel occlusion caused by in situ thrombo-occlusion (ICAS-LVO) has been regarded an important reason for refractoriness to mechanical thrombectomy (MT). To achieve better outcomes ICAS-LVO, different endovascular strategies should be explored. We aimed investigate optimal strategy ICAS-LVO. Methods: retrospectively reviewed three prospective registries of acute stroke underwent treatment. Among them, patients with ICAS-LVO...

10.3389/fneur.2021.608270 article EN cc-by Frontiers in Neurology 2021-07-05

<h3>BACKGROUND AND PURPOSE:</h3> Data on SAH after M2 mechanical thrombectomy are limited. We aimed to determine the prevalence of sulcal for occlusion, its associated predictors, and resulting clinical outcome. <h3>MATERIALS METHODS:</h3> The study retrospectively reviewed data patients with acute ischemic stroke who underwent isolated occlusion. were divided into 2 groups according presence thrombectomy. Angiographic outcomes compared. Multivariable analysis was performed identify...

10.3174/ajnr.a7594 article EN cc-by American Journal of Neuroradiology 2022-07-28

Background Identifying acute ischemic stroke (AIS) among potential cases is crucial for research based on claims data. However, the accuracy of using diagnostic codes International Classification Diseases 10th revision was less than expected. Methods From National Health Insurance Service (NHIS) data, admitted to hospitals participating in multicenter registry (Clinical Research Collaboration Stroke Korea, CRCS-K) during study period with principal or additional diagnosis I60-I64 were...

10.1371/journal.pone.0228997 article EN cc-by PLoS ONE 2020-02-14

Background: Although chest radiographs have not been utilised well for classifying stroke subtypes, they could provide a plethora of information on cardioembolic stroke.This study aimed to develop deep convolutional neural network that diagnose based radiographs.Methods: Overall, 4,064 consecutive patients with acute ischaemic were collected from prospectively maintained registry. Chest randomly partitioned into training/validation (n = 3,255) and internal test 809) datasets in an 8:2 ratio....

10.1016/j.ebiom.2021.103466 article EN cc-by-nc-nd EBioMedicine 2021-07-01

There is limited information about non-selective and contemporary data on quality of stroke care its variation among hospitals at a national level.We analysed the patients admitted to 258 acute covering entire country from Acute Stroke Quality Assessment Program, which was performed by Health Insurance Review Service 2008 2014 in South Korea. The primary outcome measure defect-free (all-or-none), based six get with guidelines-stroke performance measures (except venous thromboembolism...

10.1177/2396987319849983 article EN European Stroke Journal 2019-05-24

Patients who survive an acute phase of stroke are at risk falls and fractures afterwards. However, it is largely unknown how frequent occur in the Asian population.Patients with (< 7 days) ischemic were hospitalized between January 2011 November 2013 identified from a prospective multicenter registry Korea, linked to National Health Insurance Service claim database. The incidences investigated during first 4 years after index stroke. cumulative incidence functions (CIFs) estimated by Gray's...

10.3346/jkms.2019.34.e164 article EN cc-by-nc Journal of Korean Medical Science 2019-01-01
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