A5041492328- Multiple Sclerosis Research Studies
- Stroke Rehabilitation and Recovery
- Cerebral Palsy and Movement Disorders
- Neurology and Historical Studies
- Systemic Sclerosis and Related Diseases
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Peripheral Neuropathies and Disorders
- Acute Ischemic Stroke Management
- Autoimmune and Inflammatory Disorders Research
- Botulinum Toxin and Related Neurological Disorders
- Long-Term Effects of COVID-19
- Neuroscience, Education and Cognitive Function
- Medical Practices and Rehabilitation
- Health Systems, Economic Evaluations, Quality of Life
- Urinary Bladder and Prostate Research
- Systemic Lupus Erythematosus Research
- Mental Health and Psychiatry
- Pelvic floor disorders treatments
- Rheumatoid Arthritis Research and Therapies
- Telemedicine and Telehealth Implementation
- Intracerebral and Subarachnoid Hemorrhage Research
- Family Support in Illness
- Healthcare Systems and Practices
- Traumatic Brain Injury and Neurovascular Disturbances
- Muscle activation and electromyography studies
Valens Clinics
2016-2025
Swiss Paraplegic Center
2020
Ghent University
2020
Universitair Ziekenhuis Leuven
2020
KU Leuven
2020
Zürcher RehaZentrum Davos
2019
University of Zurich
2015
Cereneo
2015
University of Bern
1989-2010
Royal Rehabilitation Centre
2010
Multiple sclerosis (MS) patients of an inpatient rehabilitation program have been randomly assigned to exercise training (MS-ET) or nontraining group (MS-NI). Before and after 4 weeks aerobic training, a graded maximal test with measurement gas exchange lung function was administered all 26 fulfilling the inclusion criteria. Activity level, fatigue health perception were measured by means questionnaires. Twenty-six healthy persons served as control matched in respect age, gender activity...
Brain MRI was performed on 12 patients with acute disseminated encephalomyelitis (ADEM). Multifocal white matter lesions indistinguishable from those seen in multiple sclerosis (MS) were found 10. In 5 there rather extensive symmetric abnormalities the cerebral (2) or cerebellar (2), basal ganglia (1). Follow-up after intervals of 2 wks to 18 months demonstrated partial resolution abnormalities, but some persisting lesions. New at follow-up only 1 case an interval wks. Serial makes a useful...
Gadolinium-DTPA (Gd-DTPA) enhancement seen with magnetic resonance imaging in chronic relapsing experimental allergic encephalomyelitis (CREAE) corresponded sites of blood-brain barrier breakdown judged by traditional markers areas inflammatory demyelination. Duration Gd-DTPA leakage for individual lesions CREAE varied from 5 days to more than wks. By contrast, acute EAE was shorter duration (always less days). Selective observed using Gd-protein markers. Gd-albumin not always the smaller...
Background: Aerobic exercise can improve cognitive performance in healthy elderly people. Objective: The aim of this study was to investigate the influence a 3-week high-intensity aerobic programme (high-intensity training group (HIT)) on persons with multiple sclerosis (MS) compared standard (control (CT)). Methods: A total 60 MS (Expanded Disability Status Scale (EDSS): 1.0–6.5) were randomized HIT (3×/week for 20 minutes, including five 3-minute intervals at 80% peak oxygen uptake (VO...
Background: The influences of exercising on cytokine response, fatigue and cardiorespiratory values are important aspects rehabilitation in persons with multiple sclerosis (PwMS). Exercise performed within these programs is often practised water but the effects immersion PwMS have not been systematically investigated. Objective: objective this study to determine differences neurotrophin concentrations, response 3 week endurance training conducted a cycle ergometer or an aquatic bike....
Objective To evaluate feasibility and perform an explanatory analysis of the efficacy robot-assisted gait training (RAGT) in MS patients with severe walking disabilities (Expanded Disability Status Scale [EDSS] 6.0—7.5) a pilot trial. Methods Prospective, randomized, controlled clinical trial comparing RAGT conventional (CWT) group stable ( n = 35) during inpatient rehabilitation stay, 15 sessions over three weeks. All participated additionally multimodal program. The primary outcome measure...
The brain and its health are essential for our (physical mental, social, spiritual) wellbeing, being able to realize potential as individuals, also a fair, well-functioning, productive society. However, today the world is facing healthcare crisis related very high (and increasing) burden of disorders. As response this crisis, “Swiss Brain Health Plan” (SBHP) was conceptualized in context other initiatives launched value, promote, protect over entire life course. In first section position...
The authors studied standard autonomic function tests and measures of heart rate variability in 60 patients with multiple sclerosis (MS) correlated results the Fatigue Severity Scale Modified Impact Scale. found that responses fatigue resembling a hypoadrenergic orthostatic response, possibly due to sympathetic vasomotor lesion intact vagal control. Treatments control dysfunction for MS-associated deserve further study.
Multiple sclerosis (MS) is one of the most frequently observed neurological conditions in Switzerland, but data sources for country-wide epidemiological trend monitoring are lacking. Moreover, while clinical and laboratory MS research generally well established, there a gap patient-centered to inform care management, or treatment decisions policy making not only Switzerland worldwide.In light these gaps, Swiss Sclerosis Society initiated funded Registry (SMSR) an open-ended, longitudinal...
Magnetic resonance imaging was performed on 50 patients with clinically definite or probable multiple sclerosis before and 15 days after starting treatment intravenous methylprednisolone (0.5 g daily for 5 days). Scans were abnormal in 49 patients. New lesions had appeared the second scan nine individuals seven a single pre-existing lesion to have become smaller but no case seen disappear. Two showed both reduction size of an area development new indicating that corticosteroids do not appear...
Cooling of thermosensitive patients with multiple sclerosis (MS) can improve clinical symptoms. In order to study the effectiveness an advanced lightweight cooling-garment technology based on aquatic evaporation, a single-blinded balanced crossover was performed 20 Expanded Disability Status Scale score ≤6.5. The results using tight-cuff prototype for peripheral cooling suggest improvement timed-walking test, leg-strength, fine-motor skills and subjective benefits. Preliminary data heart...