A5100669687- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurosurgical Procedures and Complications
- Spinal Fractures and Fixation Techniques
- Moyamoya disease diagnosis and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrospinal fluid and hydrocephalus
- Acute Ischemic Stroke Management
- Advanced Fiber Optic Sensors
- Spine and Intervertebral Disc Pathology
- Vitamin D Research Studies
- Parkinson's Disease Mechanisms and Treatments
- Spinal Dysraphism and Malformations
- Meningioma and schwannoma management
- Spinal Hematomas and Complications
- Aortic aneurysm repair treatments
- Cervical and Thoracic Myelopathy
- Neurofibromatosis and Schwannoma Cases
- Musculoskeletal pain and rehabilitation
- Venous Thromboembolism Diagnosis and Management
- Antiplatelet Therapy and Cardiovascular Diseases
- Nuclear Receptors and Signaling
- Advanced Battery Technologies Research
Inje University Haeundae Paik Hospital
2020-2025
Inje University Busan Paik Hospital
2014-2024
Gyeongsangnam-do Agricultural Research and Extension Services
2021-2023
Korea Institute of Civil Engineering and Building Technology
2013-2022
Kyungpook National University
2022
Ulsan College
1997-2021
University of Ulsan
1997-2021
Asan Medical Center
1998-2021
Inje University
2014-2019
Dongnam Health University
2019
Transient receptor potential vanilloid type 6 (TRPV6) (ECAC2, CaT1) is the major ion channel in intestinal epithelial cell membranes responsible for calcium entry. Its expression actively regulated at transcriptional level by 1,25-dihydroxyvitamin D3 [1,25-(OH)2D3]. In this report, we identify mechanisms integral to regulation of TRPV6 1,25-(OH)2D3. Based upon hormonal responsiveness a 7-kb promoter fragment lines, used chromatin immunoprecipitation (ChIP) scanning method search possible...
Repetitive transcranial magnetic stimulation (rTMS) has been recognized as a promising intervention for treatment of stroke patients. However, most previous reports have described the short-term effects rTMS on motor performance. We conducted sham-controlled trial to evaluate long-term high-frequency recovery in subacute patients.Twenty-eight patients were randomly divided into two groups, and received either real or control rTMS. Both treatments accompanied by practice. A daily dose 1000...
The biological actions of 1,25-(OH)2D3 are mediated by the vitamin D receptor (VDR), a protein that binds to target genes and alters their expression. is also capable inducing transcription VDR gene itself. In present study, we explored both capacity induce expression in bone cells mechanism instrumental this up-regulation. After establishing ability stimulate mRNA up-regulation vivo osteoblastic cells, screened mouse locus from 20 kb upstream gene's transcriptional start site (TSS) 10...
Central nervous system (CNS) aspergillosis is a life-threatening infection primarily affecting immunocompromised patients and may lead to severe cerebral infarction through vascular invasion. However, there limited data on the treatment options for aspergillosis-induced especially surgical treatments such as superficial temporal artery (STA)-middle (MCA) bypass surgery. Herein, we present case of in 59-year-old male with progressive right eye ptosis. Specifically, he had ipsilateral MCA...
Oxidative stress is believed to contribute the pathophysiology of Parkinson's disease, in which nigrostriatal dopaminergic (DA) neurons undergo degeneration. Identification endogenous molecules that generation oxidative and vulnerability these cells critical understanding etiology this disease. Exposure tetrahydrobiopterin (BH4), obligatory cofactor for DA synthesis, was observed previously cause damage cells. To demonstrate physiological relevance observation, we investigated whether an...
Purpose We present our experiences of intra-arterial tirofiban injection through a deployed Solitaire stent as rescue therapy after failed mechanical thrombectomy in patients with acute ischemic stroke. Materials and Methods Data on 18 treated adjunctive temporarily were retrospectively reviewed. was used primary device 16 patients. Two received manual aspiration initially. If initial failed, injected intra-arterially the then subsequent performed. Results Fourteen had occlusions middle...
Abstract The proper estimation of prestressing force (PF) distribution is critical to ensure the safety and serviceability prestressed concrete (PSC) structures. Although PF can be theoretically calculated based on certain predictive equations, resulting accuracy theoretical needs further validated by comparison with reliable test data. Therefore, a Smart Strand fiber optic sensors embedded in core wire was developed applied full-scale specimen two long-span PSC girder bridges this study....
To investigate differences in cortical thickness narcolepsy patients with cataplexy and control subjects.Cortical was measured using a 3-D surface-based method that enables more accurate measurement deep sulci localized regional mapping.University hospital.We enrolled 28 33 age-and sex-matched direct for calculating the distance between corresponding vertices from inner outer surfaces.We normalized surfaces 2-D surface registration performed diffusion smoothing to reduce variability of...
OBJECTIVE The goal of this study was to evaluate factors that are associated with the need for additional posterior direct decompressive surgery after anterior lumbar interbody fusion (ALIF) or lateral (LLIF). METHODS Eighty-six adult patients who underwent ALIF LLIF degenerative spondylolisthesis and foraminal stenosis were enrolled. Patient (age, sex, number levels, visual analog scale [VAS] score leg back pain); procedure-related (cage height lordosis); radiographic measurements (disc...
Antiplatelet therapy, where regimens are tailored based on platelet function testing, has been introduced into neurointerventional surgery. This nationwide registry study evaluated the effect and safety of antiplatelet therapy in stent assisted coiling for unruptured aneurysms compared with conventional using a standard regimen.This enrolled 1686 patients 44 participating centers who received between January 1, 2019 December 31, 2019. The regimen (aspirin clopidogrel) was used all group...
We report our experience using Onyx for embolization of dural arteriovenous fistula (DAVF) under dual lumen balloon catheter flow arrest. Transfemoral cerebral angiography revealed a superior sagittal sinus (SSS) DAVF that was supplied via multiple branches the external carotid arteries, right anterior and meningeal internal artery. There no anterograde venous drainage through SSS, almost retrograde medullary cortical veins. Under general anesthesia, transvenous approach utilized to place...
Background: Nanocapsules can efficiently encapsulate therapeutic cargo for anticancer drug delivery. However, the controlled release of payload remains a challenge effective Materials & methods: We used dithiocarbamate-functionalized PAMAM dendrimer to cross-link shell arginine gold nanoparticles stabilized nanocapsule, and from nanocapsule. The ability cross-linked nanocapsule deliver hydrophobic paclitaxel B16F10 cells was demonstrated both in vitro vivo. Results: Cross-linked possesses...
Objective— To investigate the mechanistic basis underlying antirestenosis and antiatherogenic effect of pioglitazone in patients with type 2 diabetes mellitus who were undergoing zotarolimus-eluting stent implantation. Methods Results— Recent studies highlight beneficial attenuating neointimal growth after Patients coronary artery diseases randomly assigned to (n=47) or placebo Pioglitazone significantly reduced hyperplasia within stented lesion attenuated total plaque burden in-segment...
This study aimed to determine the optimal time for tracheostomy by evaluating benefits and safety of early versus late in spinal cord injury (SCI) patients.We retrospectively reviewed a total 254 patients with injury. Of them, we selected 21 who required due long-term mechanical ventilation analyzed their medical records. The were categorized into two groups. Early was performed day 1-10 from intubation 10 after 11 cases. We also evaluated duration ventilation, stay ICU complications related...