A5040196450- Intracranial Aneurysms: Treatment and Complications
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Acute Ischemic Stroke Management
- Vascular Malformations Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Neurological Complications and Syndromes
- Meningioma and schwannoma management
- Neurosurgical Procedures and Complications
- Intracerebral and Subarachnoid Hemorrhage Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebral Venous Sinus Thrombosis
- Cardiovascular Health and Disease Prevention
- Cardiovascular Issues in Pregnancy
- Spine and Intervertebral Disc Pathology
- Atrial Fibrillation Management and Outcomes
- Cerebrospinal fluid and hydrocephalus
- Migraine and Headache Studies
- Venous Thromboembolism Diagnosis and Management
- Brain Metastases and Treatment
- Retinal and Optic Conditions
- Retinal Imaging and Analysis
- Trigeminal Neuralgia and Treatments
- Orthopedic Surgery and Rehabilitation
- Advanced X-ray and CT Imaging
Korea National University of Transportation
2025
Bundang Jesaeng Hospital
2020-2024
Hallym University
2010-2019
Hangang Sacred Heart Hospital
2017-2019
Seoul National University Bundang Hospital
2010-2018
Seoul National University
2010-2017
Seoul National University Hospital
2010-2015
Makati Medical Center
2014
Chuncheon Sacred Heart Hospital
2010-2013
Boramae Medical Center
2010-2011
Purpose To evaluate the effect of middle meningeal artery (MMA) embolization on chronic subdural hematoma (CSDH) and compare treatment outcomes MMA conventional treatment. Materials Methods All consecutive patients 20 years or older with CSDH were assessed for eligibility. CSDHs a focal location, thickness 10 mm less, no mass effect, underlying conditions excluded. Seventy-two prospectively enrolled underwent (embolization group; as sole in 27 [37.5%] asymptomatic additional removal symptom...
OBJECT Moyamoya disease (MMD) is a progressive that can cause recurrent stroke. The authors undertook this retrospective case-control study with large sample size in an attempt to assess the efficacy of direct or combined revascularization surgery for ischemia adults MMD. METHODS investigated cases involving patients moyamoya presenting who visited Seoul National University Bundang Hospital and between 2000 2014. Among 441 eligible patients, 301 underwent 140 were treated conservatively....
OBJECTIVE We retrospectively evaluated whether antiplatelet preparation lowered the thromboembolic complication rate during perioperative period. METHODS reviewed 328 elective coil embolization procedures in which only microcatheters were used for coiling. No medication was prescribed before procedure 95 cases (29%, group 1), whereas therapy 233 (71%, 2; 61 [18.6%] with a single agent [aspirin or clopidogrel] and 172 [52.4%] both agents). Antiplatelet agents not given after coiling unless...
Thromboembolism is the most common complication in coiling for an unruptured aneurysm and frequent patients with high on-treatment platelet reactivity (HTPR) who are prescribed a standard antiplatelet preparation its prevention.To evaluate effect of modified compared HTPR undergoing coiling.A prospective randomized open-label active-control trial blinded outcome assessment at Seoul National University Bundang Hospital from May 27, 2013, to April 7, 2014. Patients were randomly assigned (1 1)...
To evaluate characteristics of delayed ischemic stroke after stent-assisted coil placement in cerebral aneurysms and to determine the optimal duration dual antiplatelet therapy for its prevention.This retrospective study was approved by institutional review board, requirement obtain written informed consent waived. Of 1579 patients with 1661 aneurysms, 395 (25.0%) 403 (24.3%) treated were included assigned groups stratified as early (126 [31.9%]; 3 months placement), midterm (160 [40.5%]; 6...
We investigated whether silk fibroin peptide derived from the silkworm, Bombyx mori, could inhibit inflammation and enhance anti-inflammatory activity of Tat-superoxide dismutase (Tat-SOD), which was previously reported to effectively penetrate various cells tissues exert anti-oxidative in a mouse model inflammation. Inflammation induced by topical treatment ears with 12-O-tetradecanoylphorbol-13-acetate (TPA). Histological, Western blot, reverse transcription-polymerase chain reaction data...
There have been a few studies reporting the epidemiology of moyamoya disease in Korea. Previous revealed relatively high prevalence and incidence Korea Japan. This study was designed to provide latest epidemiologic information We analyzed database comprising 50 million people covered by National Health Insurance Service calculate prevalence. The estimated eliminating duplicated records previous 3 years. summarized according age, sex, local distribution. In addition, chronological changes...
<h3>BACKGROUND AND PURPOSE:</h3> Stents are known to have hemodynamic and biologic effects in addition their mechanical scaffold effect. To determine whether stents affect long-term outcomes after coiling of unruptured aneurysms, we compared angiographic at 2 years postembolization for stent- nonstent-assisted coiled aneurysms. <h3>MATERIALS METHODS:</h3> Stent-assisted was used aneurysms unfavorable simple (neck size >4 mm dome-to-neck ratio <1.5) our practice. Therefore, 126 total...
Surgical reperfusion may be beneficial in patients with acute ischemic stroke who are ineligible for thrombolysis.To evaluate the outcome of superficial temporal artery to middle cerebral (STA-MCA) bypass and progress.The clinical radiological data 9 treated by STA-MCA requiring urgent but intra-arterial thrombolysis (IAT) were reviewed. Pooled analysis was performed published literature concerning (21 cases 2 articles).Of enrolled, symptom aggravation occurred during medical treatment 4...
Background Estimations of the intracranial aneurysm incidence require long-term follow-up a relatively large at-risk population; as result, remains largely unknown. Aims To investigate national in Korean population. Methods After excluding 18,604 potential subjects with previous history stroke (I6x.x), 998,216 were included this observational cohort. The primary endpoint was earliest date diagnosis either unruptured (UIA; I67.1) or subarachnoid hemorrhage (SAH; I60.x). We collected...
<h3>BACKGROUND AND PURPOSE:</h3> Prophylactic antiplatelet medication is beneficial in decreasing thromboembolic complications during endovascular treatment of unruptured intracranial aneurysms. The efficacy may be limited by variability individual response to medication, especially clopidogrel. We compared the 2 medications, low-dose prasugrel and clopidogrel, patients undergoing <h3>MATERIALS METHODS:</h3> From November 2014 July 2015, 194 with a total 222 aneurysms underwent at single...
Antiplatelet therapy, where regimens are tailored based on platelet function testing, has been introduced into neurointerventional surgery. This nationwide registry study evaluated the effect and safety of antiplatelet therapy in stent assisted coiling for unruptured aneurysms compared with conventional using a standard regimen.This enrolled 1686 patients 44 participating centers who received between January 1, 2019 December 31, 2019. The regimen (aspirin clopidogrel) was used all group...
Purpose To identify and apply an optimized P2Y12 reaction units (PRU) threshold for implementing modified antiplatelet preparation to prevent thromboembolic events in patients nonresponsive clopidogrel (clopidogrel nonresponders) undergoing coil embolization of unruptured aneurysms evaluate the clinical validity. Materials Methods The optimal PRU prediction was determined with Youden index post hoc analysis a previous, prospectively enrolled cohort 165 whom regimen not modified. This used...
Abstract Pulsatile tinnitus (PT) is often an initial presenting symptom of dural arteriovenous fistula (dAVF), but it may be overlooked or diagnosed late if not suspected on diagnostic work-up. Here, we assess anatomical features, treatment outcomes, and clinical implications patients with PT due to dAVF. Of 220 who were dAVF between 2003 2014, 30 (13.6%) presented only as their symptom. The transverse-sigmoid sinus (70.0%) was the most common site, followed by hypoglossal canal (10.0%)...
Objective :The authors evaluated the accuracies and ease of use several commonly used microanastomosis training models (synthetic tube, chicken wing, living rat model).Methods : A survey was conducted among neurosurgeons neurosurgery residents at a workshop held in 2009 authors' institute.Questions addressed model accuracy (similarity to real vessels actual procedures) practicality (availability materials application daily practice).Answers each question were rated using 5-point...
Postoperative seizure, well-known in association with other pathologies, has been rarely discussed adult moyamoya disease.We evaluated postoperative seizures patients undergoing revascularization surgery.From 2001 to 2007, 43 disease underwent 53 surgeries, consisting of direct bypass or without indirect bypass. Incidence and profile were investigated, evaluation influencing factors. Multivariable analysis using a generalized estimation equation was performed determine which factors related...
The authors aimed to assess whether the prevalence of intracranial aneurysms in patients with meningiomas was higher than that a healthy population.The performed hospital-based case-control study 300 newly diagnosed and 900 age- sex-matched controls without history brain tumors evaluate any associations between meningiomas. Unconditional multivariate logistic regression models were used for comparisons.Intracranial identified 23 (7.7%) 24 (2.7%; p < 0.001). There significant association (OR...
Neurogenic pulmonary edema (NPE) leading to cardiopulmonary dysfunction is a potentially life-threatening complication in patients with central nervous system lesions. This case report describes 28-yr woman fulminant NPE, which was refractory conventional respiratory treatment, following the rupture of an aneurysm. She treated successfully extracorporeal membrane oxygenation (ECMO), although ECMO therapy generally contraindicated neurological injuries such as brain trauma and diseases that...