A5018982215- Anesthesia and Sedative Agents
- Anesthesia and Pain Management
- Cardiac, Anesthesia and Surgical Outcomes
- Airway Management and Intubation Techniques
- Anesthesia and Neurotoxicity Research
- Nausea and vomiting management
- Respiratory Support and Mechanisms
- Intraoperative Neuromonitoring and Anesthetic Effects
- Tracheal and airway disorders
- Neuroscience and Neuropharmacology Research
- Intensive Care Unit Cognitive Disorders
- Hemodynamic Monitoring and Therapy
- Zebrafish Biomedical Research Applications
- Nitric Oxide and Endothelin Effects
- Pediatric Pain Management Techniques
- Head and Neck Surgical Oncology
- Liver Disease and Transplantation
- Pain Management and Opioid Use
- Optical Imaging and Spectroscopy Techniques
- Cancer, Hypoxia, and Metabolism
- Restraint-Related Deaths
- Organ Transplantation Techniques and Outcomes
- Artificial Intelligence in Healthcare and Education
- Food Allergy and Anaphylaxis Research
- Neuropeptides and Animal Physiology
Korea University Medical Center
2014-2024
Korea University
2015-2024
Weatherford College
2021
Creative Commons
2021
ORCID
2020
Ansan University
2020
Novem (Netherlands)
2016
Airway driving pressure, easily measured as plateau pressure minus PEEP, is a surrogate for alveolar stress and strain. However, the effect of its targeted reduction remains unclear.In this multicentre trial, patients undergoing lung resection surgery were randomised to either group (n=650) receiving an recruitment/individualised PEEP deliver lowest or conventional protective ventilation with fixed 5 cm H2O. The primary outcome was composite pulmonary complications within 7 days...
Surgical pleth index (SPI) monitoring is a representative, objective nociception-monitoring device that measures nociception using photoplethysmographic signals. It easy to apply patients and the numerical calculation formula intuitively understand; therefore, its clinical interpretation simple. Several studies have demonstrated efficacy utility. Compared with hemodynamic parameters, SPI can detect degree of during surgery under general anesthesia greater accuracy, therefore provide better...
Abstract Background: To compare surgical pleth index (SPI)-guided analgesia with conventional by evaluating intraoperative analgesic requirements, postoperative pain, and emergence agitation in children. Methods: This study was designed as a parallel, two-arm, double-blind, randomized controlled trial. Forty-five children undergoing elective adenotonsillectomy were randomly allocated to SPI-guided group (SPI-guided group, n = 21) or control (conventional 24). Anesthesia maintained...
Abstract Background During general anesthesia, the surgical pleth index (SPI) monitors nociception. The evidence of SPI in elderly remains scarce. We aimed to investigate whether there is a difference perioperative outcomes following intraoperative opioid administration according value versus hemodynamic parameters (heart rate or blood pressure) patients. Methods Patients aged 65–90 years who underwent laparoscopic colorectal cancer surgery under sevoflurane/remifentanil anesthesia were...
Background: The surgical pleth index (SPI) is proposed for titration of analgesic drugs during general anesthesia. Several reports have investigated the effect SPI on consumption opioids including remifentanil, fentanyl, and sufentanil anesthesia, but there are no about oxycodone. We aimed to investigate intravenous oxycodone between SPI-guided analgesia conventional practices sevoflurane anesthesia in patients undergoing thyroidectomy. Methods: Forty-five elective thyroidectomy were...
We aimed to investigate operating conditions, postoperative pain, and overall satisfaction of surgeons using deep neuromuscular blockade (NMB) vs. no NMB in patients undergoing lumbar spinal surgery under general anesthesia. Eighty-three fusion were randomly assigned receive (n = 43) or 40). In the deep-NMB group, rocuronium was administered maintain (train-of-four count 0, post-tetanic 1–2) until end surgery. no-NMB sugammadex 4 mg/kg at train-of-four (TOF) 0–1 2 TOF ≥2 reverse 10 min after...
Background: Fentanyl is one of the most widely used opioids for intravenous patient-controlled analgesia (IV-PCA).Sufentanil, a fentanyl analog, suitable postoperative pain control because it has no active metabolites and shows higher therapeutic index lower frequency respiratory suppression than fentanyl.This study aimed to compare two relief on basis analgesic efficacy, adverse effects, patient satisfaction.Methods: Sixty-four patients undergoing total laparoscopic hysterectomy were...
Hyperexcitatory behaviors occurring after sevoflurane anesthesia are of serious clinical concern, but the underlying mechanism is unknown. These may result from potentiation by GABAergic depolarization/excitation in neocortical neurons, cells implicated genesis consciousness and arousal. The current study sought to provide evidence for this hypothesis with rats, neurons which known respond GABA (γ-aminobutyric acid) at early stages development (i.e., until second postnatal week)...
Background Coughing, hypertension, tachycardia, and even laryngospasm can occur due to airway irritation during emergence from anesthesia. We investigated the effect of maintaining a sufentanil infusion anesthesia by evaluating incidence cough recovery profiles at extubation. Methods In total, eighty-four patients undergoing an elective laparoscopic hysterectomy were randomly divided into two groups control group. During emergence, was administered in rate 0.2 µg/kg/hr (Group S1) or 0.3 S2),...
Background We investigated the effects of combined administration nefopam, a N-methyl-D-aspartate receptor antagonist and low dose remifentanil, on early postoperative pain analgesic requirement. Methods Fifty patients scheduled to undergo mastoidectomy tympanoplasty were randomized be given either nefopam 40 mg mixed with normal saline 100 ml (Group N) or an equal amount C) before anesthesia induction. Anesthesia was maintained 5-6 vol% desflurane remifentanil 0.05-0.15 µg/kg/min during...
In many countries, routine clinical anaesthesia does not always involve neuromuscular monitoring. these settings, the efficacy and safety of sugammadex use has yet been confirmed. We investigated in absence One hundred forty patients who underwent laryngeal microsurgery with rocuronium as a blocking agent, without monitoring device, were retrospectively investigated. The randomly chosen among all met inclusion criteria at tertiary university hospital between July 2013 February 2015 allocated...
Patients with cervical spine instability and limited range of motion are challenge to anesthesiologists. It is important consider alternatetive methods for securing the airway while maintaining neutral position minimizing neck motion, because these patients at increased risk tracheal intubation failure neurologic injury during management or change. We experienced two cases that had severe due fusion entire spine. One patient was a 6-year-old girl weighing 12.7 kg Klippel-Feil syndrome...
Purpose: Recent studies have shown the potential benefits of pressure-controlled ventilation-volume guaranteed (PCV-VG) compared to volume-controlled ventilation (VCV), but results were not impressive. We assessed effects PCV-VG versus VCV in elderly patients by using lung ultrasound score (LUS). Patients and methods: Elderly (aged 65–90 years) scheduled for hip joint surgery randomly assigned either or group during general anesthesia. LUS mechanical ventilator parameters evaluated before...
Abstract Background Hypoxia inhibits the uptake of glutamate (a major neurotransmitter in brain closely related to cognitive function) into cells, and initial response cells cortical hypoxia depends on glutamate. Previous studies have suggested that magnesium may protective effects against hypoxic injuries. In particular, l -threonate (MgT) increase ion concentrations better than MgSO 4 improve function. Methods We evaluated cell viability under conditions MgT- -treated human SH-SY5Y...
Background The aim of this study was to compare the streamlined liner pharynx airway (SLIPA) with classic laryngeal mask when used by novice personnel. Methods There were 114 patients enrolled into who underwent general anesthesia randomly allocated one 2 groups; LMA group (n = 57) or SLIPA 57). After insertion, insertion success rate, time, and hemodynamic responses accessed. surgery, postoperative morbidity (sore throat, dysphonia, dysphagia) evaluated. Results successfully inserted in 96%...
The standard bifrontal application of the bispectral index (BIS) sensor interferes with operative field in neurosurgery and plastic surgery. aim this study was to compare frontal BIS position an alternative across mandible.Two BIS™ Quatro sensors (Aspect Medical Systems, Newton, MA, USA) mounted on mandibular regions were connected Vista™ monitors each patient during general anesthesia. Data from collected at awake, loss consciousness, intubation, incision, every 30 minutes intraoperative...