- Traumatic Brain Injury and Neurovascular Disturbances
- Meningioma and schwannoma management
- Glioma Diagnosis and Treatment
- Neurosurgical Procedures and Complications
- Brain Metastases and Treatment
- Traumatic Brain Injury Research
- Intracerebral and Subarachnoid Hemorrhage Research
- Neurological disorders and treatments
- Intracranial Aneurysms: Treatment and Complications
- Head and Neck Surgical Oncology
- Acute Myocardial Infarction Research
- Parkinson's Disease Mechanisms and Treatments
- Pituitary Gland Disorders and Treatments
- Heart Failure Treatment and Management
- Cerebral Venous Sinus Thrombosis
- Epilepsy research and treatment
- Acute Ischemic Stroke Management
- Cancer Cells and Metastasis
- Cardiac Imaging and Diagnostics
- Lung Cancer Research Studies
- S100 Proteins and Annexins
- Sinusitis and nasal conditions
- Cerebrovascular and Carotid Artery Diseases
- Spinal Fractures and Fixation Techniques
- Coronary Interventions and Diagnostics
Korea University Medical Center
2016-2025
Hyupsung University
2019-2024
Catholic University of Daegu
2021
Korea University
2006-2019
Armed Forces Capital Hospital
2019
MizMedi Hospital
2002-2018
Hanseo University
2008-2016
Konyang University Hospital
2015
Hallym University
1999-2014
Konyang University
2014
Abstract Introduction The reported mortality rates range from 28% to 100% in burn patients who develop acute kidney injury (AKI) and 50% among such treated with renal replacement therapy. Recently, the serum cystatin C plasma urine neutrophil gelatinase-associated lipocalin (NGAL) levels have been introduced as early biomarkers for AKI; of these are known increase 24 48 hours before creatinine increase. In this study, we aimed estimate diagnostic utility NGAL post-burn period predicting AKI...
Optimal treatment decision and estimation of the prognosis in traumatic brain injury (TBI) is currently based on demographic clinical predictors. But sometimes, there are limitations these factors. In this study, we analyzed three central nervous system biomarkers TBI patients, will discuss roles applications TBI.From July 2013 to August 2014, a total 45 patients were included. The serum was obtained at time hospital admission, extracted with centrifugal process. It for level S-100 beta...
Although spontaneous intracranial hypotension (SIH) is an increasingly recognized syndrome, the long-term outcomes have not been established. We conducted a follow-up study to clarify clinical features and of patients with this disorder.We performed retrospective in 13 consecutive SIH treated between 1998 2003. The diagnosis was made on basis symptoms, lumbar puncture, radiological studies (e.g. brain magnetic resonance imaging, spine computed tomographic myelography) radionuclide...
The safety of the stent-assisted coil embolization (SAC) technique for acutely ruptured aneurysms has not been established yet. SAC is believed to be associated with a high risk thromboembolic and hemorrhagic complications in acute subarachnoid hemorrhage (SAH). aim this study was evaluate efficacy setting aneurysm.
Extra-domain B of fibronectin (EDB-FN) is an alternatively spliced form with high expression in the extracellular matrix neovascularized tissues and malignant cancer cells.In this study, we evaluated practicality using EDB-FN as a biomarker therapeutic target for gliomas (MGs), representative intractable diseases involving brain tumors.Methods: The microarray-and sequence-based patient transcriptomic database 'Oncopression' tissue microarray MG samples were analyzed.EDB-FN data extracted...
To determine the utility of perfusion MR imaging in differential diagnosis brain tumors.Fifty-seven patients with pathologically proven tumors (21 high-grade gliomas, 8 low-grade lymphomas, 6 hemangioblastomas, 7 metastases, and various other tumors) were included this study. Relative cerebral blood volume (rCBV) time-to-peak (TTP) ratios quantitatively analyzed rCBV grade each tumor was also visually assessed on an map.The highest seen followed by lymphomas. There no significant difference...
Abstract. Purpose: We aimed to evaluate the effectiveness of bicanalicular double silicone intubation in dacryocystorhinostomy (DCR) and canaliculoplasty for distal or common canalicular obstruction. Methods: reviewed medical records patients with obstruction who had undergone (insertion two tubes into each canaliculus) during external DCR canaliculoplasty. subjects same surgery a single as control material. The were removed at around 6 months after surgery. Anatomical functional success...
In Brief Purpose: To evaluate the cytologic features of conjunctival epithelium in anophthalmic sockets with an ocular prosthesis, using impression cytology technique and to determine clinical factors associated these changes. Methods: a prospective case-controlled study, 40 consecutive unilateral patients who wore prosthesis were recruited. A questionnaire on care included total wearing period, frequency cleaning, polishing, cleaning solution, eye drop use. The degree inflammation socket...
Although the functional significance of neuronal phospholipase D (PLD) is being recognized, little known about its regulatory role in cells. To elucidate mechanism PLD, we investigated PLD2-binding protein from rat brain cytosol. During fractionation cytosol by four-column chromatography, a 62-kDa PLD2-interacting was detected PLD2 overlay assay and identified as collapsin response mediator protein-2 (CRMP-2), which controls axon guidance outgrowth. Using bacterially expressed...
Purpose: To investigate the efficacy of lacrimal silicone intubation for management epiphora in patients who have previously undergone anatomically successful dacryocystorhinostomy (DCR).Methods: The authors recruited 13 (4 male, 9 female) had persistent after an primary external DCR and conducted through site.Results: Mean patient age was 54.2 years (range 42-80) mean follow-up 13.8 months 6-30).Epiphora resolved all following intubation.Spontaneous tube extrusion occurred three patients,...
OBJECTIVE Deep brain stimulation is an alternative treatment for advanced Parkinson's disease. Levodopa medications are usually discontinued the night before surgery to localize optimal response site intraoperative macrostimulation. However, abrupt withdrawal of medication may result in side effects. We report a case parkinsonism-hyperpyrexia syndrome (PHS), rare complication resulting from discontinuation antiparkinsonian medication, after deep (DBS) procedure bilateral subthalamic-nucleus...
Abstract Objective Myelinated Schwann cells (SCs) in adult peripheral nerves dedifferentiate into immature demyelinating neuropathies and Wallerian degeneration. This plastic SC change is actively involved the myelin destruction clearance as SCs (DSCs). In inherited neuropathy, pathologically differentiated dysmyelinated constitute main nerve pathology. Methods We investigated whether this status human neuropathic could be determined by patient sera to develop disease‐relevant serum...
Magnesium ions have been shown to be a promising treatment for brain lesions caused by traumatic injury (TBI), as well the associated acute neurodegeneration and progressive functional deficits. This study investigated effects of magnesium on expression cell death/survival related proteins following TBI. Male Sprague-Dawley (SD) rats (n = 66, 280-320 g body weight) were subjected sham surgery alone 14), or followed lateral fluid percussion moderate severity 52, 2.4-2.7 atm). The injured...