- Cardiac Valve Diseases and Treatments
- Coronary Interventions and Diagnostics
- Cardiac Imaging and Diagnostics
- Infective Endocarditis Diagnosis and Management
- Peripheral Artery Disease Management
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Atrial Fibrillation Management and Outcomes
- Vascular Procedures and Complications
- Aortic Disease and Treatment Approaches
- Cardiac Arrhythmias and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Structural Anomalies and Repair
- Aortic aneurysm repair treatments
- Acute Kidney Injury Research
- Renal and Vascular Pathologies
- Cardiovascular and Diving-Related Complications
- Peripheral Nerve Disorders
- Cerebrovascular and Carotid Artery Diseases
- Cardiac pacing and defibrillation studies
- Lipoproteins and Cardiovascular Health
- Mechanical Circulatory Support Devices
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Orthopaedic implants and arthroplasty
Sapporo Science Center
2017-2025
San Raffaele University of Rome
2017-2019
EMO GVM Centro Cuore Columbus
2017-2019
Mylan (Switzerland)
2018
Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele
2017
Vita-Salute San Raffaele University
2017
Istituti di Ricovero e Cura a Carattere Scientifico
2017
Shonan Kamakura General Hospital
2016
Sapporo Higashi Tokushukai Hospital
2011-2015
Chonnam National University
2012
Data on the performance of latest-generation SAPIEN 3 Ultra RESILIA (S3UR) valve in patients who undergo transcatheter aortic replacement (TAVR) are scarce.
Abstract Background and Aims The association between periprocedural change in tricuspid regurgitation (TR) outcomes patients undergoing mitral transcatheter edge-to-edge repair (M-TEER) is unclear. This study aimed to examine the prognostic value of TR before after M-TEER. Methods Patients OCEAN-Mitral registry were divided into four groups according baseline post-procedure echocardiographic assessments: no TR/no (no TR), TR/significant (new-onset significant (normalized (residual TR) (all...
Limited data are available regarding clinical outcomes after percutaneous left atrial appendage closure using WATCHMAN FLX (WM-FLX) and WATCHMAN-2.5 (WM2.5) devices in Asian patients.
Abstract Background and Aims The efficacy safety of early sacubitril/valsartan (Sac/Val) initiation after acute heart failure (AHF) has not been demonstrated outside North America. present study aimed to evaluate the effect in-hospital Sac/Val therapy an AHF episode on N-terminal pro-B-type natriuretic peptide (NT-proBNP) level in Japanese patients. Methods This was investigator-initiated, multicentre, prospective, randomized, open-label, blinded-endpoint pragmatic trial. After haemodynamic...
The incidence of contrast-induced acute kidney injury (CI-AKI) is particularly high in patients with severe chronic disease (CKD). Novel contrast-sparing strategies are warranted to guarantee the benefit revascularization this challenging and growing patient population. We aimed evaluate feasibility an ultra-low contrast volume percutaneous coronary intervention (ULC-PCI) protocol CKD. ULC-PCI based on prespecification maximum be administered, extensive intravascular ultrasound (IVUS) and/or...
This case discusses the retrieval of a pacemaker with vegetation from 78-year-old man. It suggests that grasping side Micra body and pulling into Agilis sheath is possible technique for retrieval.
Serial intravascular ultrasound (IVUS) was used to compare the effects of moderate doses rosuvastatin and atorvastatin on plaque regression in patients with intermediate coronary stenosis.This a prospective, randomized, comparative study for lipid-lowering therapy 20mg (n=65) 40mg (n=63) using serial IVUS (baseline 11-month follow-up). Efficacy parameters included changes total atheroma volume (TAV) percent (PAV) from baseline follow-up. Changes TAV (-4.4±7.3 vs. -3.6±6.8mm(3), P=0.5) PAV...
Percutaneous left atrial appendage closure (LAAC) reduces the incidence of stroke/bleeding events in patients with non-valvular fibrillation, high risk stroke, and contraindication continuing anticoagulation therapy. Of them, heart failure may remain at these after LAAC.
The direct-acting oral anticoagulant (DOAC) score has been validated for assessing the bleeding risk in patients with atrial fibrillation (AF). However, data on DOAC scores undergoing percutaneous left appendage closure (LAAC) is limited. This study aimed to evaluate predictive impact of clinical events following LAAC and compare it that HAS-BLED (Hypertension, Abnormal renal liver function, Stroke, Bleeding history or predisposition, Labile international normalized ratio [INR], Elderly [age...
Abstract Background The efficacy of transcatheter closure for patent foramen ovale (PFO) , which is considered a cause cerebral infarction, has been reported. PFO often becomes apparent only during the Valsalva maneuver, making its diagnosis sometimes challenging. As method to overcome inadequate maneuvers, cases using party balloon inflation maneuver have However, there are no verified reports on actual effectiveness in daily clinical practice. Purpose To investigate revealing " masked PFO....
Background In patients with sarcoidosis, cardiac involvement is a crucial prognostic factor leading to severe cardiovascular events. Mitral regurgitation (MR) predisposes drug‐refractory heart failure; however, MR in sarcoidosis (CS) has been scarcely investigated and its therapeutic approach remains unclear. This study aimed investigate the clinical impact of transcatheter edge‐to‐edge repair CS. Methods Patients CS‐related ventricular functional were compared those other nonischemic...
Abstract Although the effectiveness of snare techniques during self-expandable transcatheter aortic valve replacement (TAVR) in horizontal aorta has been reported, detailed technical guidance, such as identifying optimal snaring locations and timing, remains limited. This report highlights challenges TAVR aortas, demonstrating that strategically repositioning to poorly coaxialized segments delivery system facilitates passage subsequent coaxial deployment.
Abstract Aims Plasma volume status (PVS) is recognized as a marker of systemic congestion, but its clinical utility in patients with mitral regurgitation (MR) undergoing transcatheter edge‐to‐edge valve repair (M‐TEER) has not been well established. This study aimed to evaluate the prognostic significance PVS these patients. Methods and results Data from 3763 who underwent M‐TEER were analysed Japanese multicentre registry. Patients classified into functional MR (FMR) degenerative (DMR)...
Mineralocorticoid receptor antagonists (MRAs) are integral components of medical therapy for patients with heart failure reduced ejection fraction. However, implication MRA dosing in older undergoing transcatheter edge-to-edge mitral valve repair (TEER) secondary regurgitation remains uncertain. The authors aimed to investigate the prognostic impacts receiving TEER regurgitation. This study included who underwent and were enrolled OCEAN (Optimized CathEter vAlvular iNtervention)-Mitral...