A5100769800- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiac Imaging and Diagnostics
- Antiplatelet Therapy and Cardiovascular Diseases
- Cardiac Valve Diseases and Treatments
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Cardiac Structural Anomalies and Repair
- Mechanical Circulatory Support Devices
- Atrial Fibrillation Management and Outcomes
- Lipoproteins and Cardiovascular Health
- Cardiac Arrest and Resuscitation
- Bone Tissue Engineering Materials
- Venous Thromboembolism Diagnosis and Management
- Influenza Virus Research Studies
- Respiratory viral infections research
- Cardiac, Anesthesia and Surgical Outcomes
- Infective Endocarditis Diagnosis and Management
- Lipid Membrane Structure and Behavior
- Dental Implant Techniques and Outcomes
- Cardiac Health and Mental Health
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Supramolecular Self-Assembly in Materials
- Viral gastroenteritis research and epidemiology
Chonnam National University Hospital
2016-2025
Dunsan Korean Medicine Hospital
2025
Ministry of Health and Welfare
2015-2024
Chonnam National University
2009-2024
Illinois College
2015-2024
Severance Hospital
2023-2024
Yonsei University
2003-2024
University of Illinois Urbana-Champaign
2015-2024
Hanyang University
2024
Gyeongsang National University
2019-2024
<h3>Importance</h3> Depression has been associated with poorer medical outcomes in acute coronary syndrome (ACS), but there are few data on the effects of antidepressant treatment long-term prognosis. <h3>Objective</h3> To investigate effect major adverse cardiac events (MACE) escitalopram depression patients recent ACS. <h3>Design, Setting, and Participants</h3> Randomized, double-blind, placebo-controlled trial conducted among 300 ACS enrolled from May 2007 to March 2013, follow-up...
Abstract Aims In patients with acute myocardial infarction (MI) and multivessel coronary artery disease, percutaneous intervention (PCI) of non-infarct-related reduces death or MI. However, whether selective PCI guided by fractional flow reserve (FFR) is superior to routine angiography alone unclear. The current trial sought compare FFR-guided angiography-guided for lesions among MI disease. Methods results Patients disease who had undergone successful the infarct-related were randomly...
Although venoarterial extracorporeal membrane oxygenation (VA-ECMO) is beneficial for the treatment of profound cardiogenic shock, peripheral VA-ECMO cannulation can increase left ventricular afterload, thus compromising myocardial recovery. We investigated whether early routine unloading reduce 30-day mortality compared with conventional approach in patients shock undergoing VA-ECMO.
Myocardial infarction (MI) is a major cause of death worldwide. After the occurrence MI, heart frequently undergoes serious pathological remodeling, leading to excessive dilation, electrical disconnection between cardiac cells, and fatal functional damage. Hence, extensive efforts have been made suppress remodeling promote repair infarcted heart. In this study, we developed hydrogel patch that can provide mechanical support, conduction, tissue adhesiveness aid in recovery an function....
The extracellular domain of M2 (M2e), a small ion channel membrane protein, is well conserved among different human influenza A virus strains. To improve the protective efficacy M2e vaccines, we genetically engineered tandem repeat epitope sequences (M2e5x) human, swine, and avian origin viruses, which was expressed in membrane-anchored form incorporated virus-like particles (VLPs). M2e5x protein with transmembrane hemagglutinin (HA) effectively into VLPs at several 100-fold higher level...
The infarcted heart undergoes irreversible pathological remodeling after reperfusion involving left ventricle dilation and excessive inflammatory reactions in the heart, frequently leading to fatal functional damage. Extensive attempts have been made attenuate hearts using cardiac patches anti-inflammatory drug delivery. In this study, we developed a paintable adhesive hydrogel patch dextran-aldehyde (dex-ald) gelatin, incorporating protein, ANGPTL4, into for sustained release directly...
The long-term effects of early left ventricular unloading after venoarterial extracorporeal membrane oxygenation (VA-ECMO) remain unclear.
Ultrasound-guided acupuncture is a novel technique that utilizes ultrasonography to visualize needle placement in real-time, enhancing precision and reducing adverse events. In South Korea, the dual medical system has led disputes over Korean Medicine doctors’ use of biomedical devices. However, 2022, Supreme Court ruled ultrasound devices not illegal, enabling broader clinical application. involves inserting precise depth reach targeted tissue while applying manual techniques based on...
Duck hepatitis virus type 1 (DHV-1) was previously classified as an enterovirus, based primarily on observed morphology and physicochemical properties of the virion. The complete nucleotide sequences two strains (DRL-62 R85952) DHV-1 have been determined. Excluding poly(A) tail, genomes are 7691 7690 nt, respectively, contain a single, large open reading frame encoding polyprotein 2249 aa. genome is organized those members family Picornaviridae : 5′ untranslated region...
Even when phenotypic differences are large between natural or domesticated strains, the underlying genetic basis is often complex, and causal genomic regions need to be identified by quantitative trait locus (QTL) mapping. Unfortunately, QTL positions typically have confidence intervals, which can, for example, lead one being masked another, two closely linked loci detected as a single QTL. One strategy increase power of precisely localizing small effect QTL, use an intercross approach...
Feasibility of coronary angiography (CAG) and percutaneous intervention (PCI) via left snuffbox approach is still concerned. We aimed to investigate efficacy safety the for CAG PCI.Left was tried in 150 patients who planned perform or PCI suspected myocardial ischemia between 1 November 2017 31 March 2018.Success rate radial artery (RA) cannulation 88.0% (n=132). Among 132 individuals, 58 (43.9%) acute syndrome (ACS) were included. The diameter RA significantly smaller than conventional...
Supported lipid bilayers (SLBs) are widely studied model membrane platforms that compatible with various surface-sensitive measurement techniques. SLBs typically formed on silica-based materials, and there numerous possible fabrication routes involving either bottom-up molecular self-assembly or vesicle adsorption rupture. In between these two classes of strategies lies an emerging approach based depositing quasi-two-dimensional lamellar, bicellar disks composed a mixture long-chain...
Abstract Background This study aimed to evaluate the benefit of brachial-ankle pulse wave velocity (baPWV) as a noninvasive marker arterial stiffness for prediction all-cause and cause-specific mortality in patients with type 2 diabetes. Methods multicenter prospective observational analyzed 2308 diabetes between 2008 2018. The were categorized according quartiles baPWV. Cause was determined using death certificates patient clinical records. We estimated proportional rates from all causes,...
Extraordinary performance at elevated temperature is achieved for high-voltage spinel-phase LiNi0.5 Mn1.5 O4 cathodes prepared using an adipic-acid-assisted sol-gel technique and doped with vanadium. V-substitution in the Li sites (Wykoff position 8a) confirmed by V K-edge X-ray absorption spectroscopy Rietveld refinement (Li0.995 V0.005 Ni0.5 ). V-doped delivered a reversible capacity of approximately 130 142 mAh g(-1) ambient conditions, respectively. Furthermore, Li0.995 phase rendered 94...
The interaction of single-chain lipid amphiphiles with phospholipid membranes is relevant to many scientific fields, including molecular evolution, medicine, and biofuels. Two widely studied compounds within this class are the medium-chain saturated fatty acid, capric its monoglyceride derivative, monocaprin. To date, most studies about these have involved in vitro evaluation their biological activities, while mechanistic details how acid monocaprin interact bilayers remain elusive. Herein,...
A nanoplasmonic ruler method is presented in order to measure the deformation of adsorbed, nm-scale lipid vesicles on solid supports. It demonstrated that single adsorbed undergo greater silicon oxide over titanium oxide, offering direct experimental evidence support membrane tension-based theoretical models supported bilayer formation.
Novel nanodiamond-gold nanocomposites (NDAus) are prepared, and their oxidative catalytic activity is examined. Gold nanoparticles deposited on carboxylated nanodiamonds (NDs) by in situ chemical reduction of gold precursor ions to produce NDAus, which exhibit for the oxidation o-phenylenediamine presence hydrogen peroxide similarly a peroxidase. This remarkable exhibited only nanoparticle-decorated NDs not observed either Au or separately. Kinetic catalysis studies show that NDAus ping-pong...
Background: Recently, interventional cardiologists have been increasingly interested in snuffbox approach for coronary angiography (CAG) and percutaneous intervention (PCI).However, there is lack of data regarding distal radial artery (RA) diameter according to gender.Therefore, the aim herein was investigate gender differences RA diameter.Methods: Left done 117 patients who had planned CAG or PCI suspected myocardial ischemia between 1 December 2017 28 February 2018 at Chonnam National...