A5057103601- Antiplatelet Therapy and Cardiovascular Diseases
- Acute Myocardial Infarction Research
- Coronary Interventions and Diagnostics
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Lipoproteins and Cardiovascular Health
- Cardiac Imaging and Diagnostics
- Inflammatory mediators and NSAID effects
- Diabetes Treatment and Management
- Cardiac, Anesthesia and Surgical Outcomes
- Peripheral Artery Disease Management
- Heart Failure Treatment and Management
- Cardiovascular Health and Disease Prevention
- Platelet Disorders and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Pharmacology and Obesity Treatment
- Cardiac Arrhythmias and Treatments
- Blood Pressure and Hypertension Studies
- Cardiac Arrest and Resuscitation
- Cardiovascular Function and Risk Factors
- Synthesis of β-Lactam Compounds
- Cardiac Structural Anomalies and Repair
- Analytical Methods in Pharmaceuticals
- Respiratory Support and Mechanisms
- Gastric Cancer Management and Outcomes
Chung-Ang University Hospital
2020-2025
Chung-Ang University
2021-2025
New Generation University College
2012-2025
National University College
2012-2025
Seoul National University Bundang Hospital
2025
CHA Bundang Medical Center
2024
CHA University
2024
Gyeongsang National University
2014-2023
Samsung (South Korea)
2023
Chonnam National University Hospital
2023
Abstract East Asian patients have reduced anti-ischemic benefits and increased bleeding risk during antithrombotic therapies compared with Caucasian patients. As potent P2Y12 receptor inhibitors (e.g., ticagrelor prasugrel) direct oral anticoagulants are commonly used in current daily practice, the unique risk–benefit trade-off Asians has been a topic of emerging interest. In this article, we propose updated evidence future directions treatment
Background— As compared with whites, East Asians more often carry the cytochrome P450 ( CYP ) 2C19 loss-of-function (LOF) allele CYP2C19*3 variant. The influence of CYP2C19 LOF alleles *2 and *3 on clopidogrel response clinical outcomes in acute myocardial infarction (AMI) has not been reported. We sought to evaluate effect variants pharmacodynamics long-term prognosis these patients. Methods Results— Patients who survived an AMI (n=266) were enrolled a single-center registry. Predischarge...
Atherothrombotic events are influenced by systemic hypercoagulability and fibrinolytic activity. The present study evaluated thrombogenicity indices their prognostic implications according to disease acuity.From the consecutive patients undergoing percutaneous coronary intervention (PCI), those with (n = 2705) were grouped acuity [acute myocardial infarction (AMI) vs. non-AMI]. Thrombogenicity measured thromboelastography (TEG). Blood samples for TEG obtained immediately after insertion of...
Given the rapidly growing burden of cardiovascular disease (CVD) in Asia, this study forecasts CVD and associated risk factors Asia from 2025 to 2050.
Due to the absence of differential guidelines for heart failure with tachyarrhythmia, it is difficult diagnose tachycardia-induced cardiomyopathy (TIC) at initial visit. Furthermore, clinical outcomes rate versus rhythm control in TIC are unclear.
Optimal platelet inhibition is an important therapeutic adjunct in patients acute myocardial infarction (AMI) undergoing coronary stenting. Whether adjunctive cilostazol to dual antiplatelet therapy (triple therapy) can inhibit enhanced reactivity with AMI yet has not been determined. The aim of this study was assess the degree by triple AMI.Immediately after emergency room arrival, received clopidogrel (600-mg loading dose, followed 75 mg daily) and aspirin (300-mg dose 200 daily throughout...
<h3>Background</h3> Although East Asians carry the cytochrome P450 (CYP) <i>2C19*2</i> allele more frequently than do Caucasians, impact of <i>CYP2C19*2</i> on clopidogrel pharmacodynamics and clinical outcomes is unknown. <h3>Objective</h3> To evaluate effect <i>CYP2C19</i> variants long-term prognosis in Asian patients with drug-eluting stents (DES). <h3>Methods</h3> DES-treated taking dual antiplatelet therapy were enrolled from a Korean multicentre genetic registry. The was genotyped...