A5079503932- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Health and Disease Prevention
- Cardiovascular Function and Risk Factors
- Cardiovascular Disease and Adiposity
- Blood Pressure and Hypertension Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Cerebrovascular and Carotid Artery Diseases
- Heart Rate Variability and Autonomic Control
- Heart Failure Treatment and Management
- Cardiac pacing and defibrillation studies
- Mechanical Circulatory Support Devices
- Ultrasound and Hyperthermia Applications
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrhythmias and Treatments
- Cardiac Health and Mental Health
- Hemodynamic Monitoring and Therapy
- Peripheral Artery Disease Management
- Optical Imaging and Spectroscopy Techniques
- Eosinophilic Disorders and Syndromes
- Thermoregulation and physiological responses
- Muscle activation and electromyography studies
- Tuberous Sclerosis Complex Research
- Aortic aneurysm repair treatments
Seoul National University
2022-2025
Boramae Medical Center
2022-2025
Seoul Metropolitan Government
2023-2024
New Generation University College
2023-2024
Samsung Medical Center
2016-2023
Sungkyunkwan University
2016-2023
National University College
2023
Chung-Ang University Hospital
2023
Abstract Aims In patients with acute myocardial infarction (MI) and multivessel coronary artery disease, percutaneous intervention (PCI) of non-infarct-related reduces death or MI. However, whether selective PCI guided by fractional flow reserve (FFR) is superior to routine angiography alone unclear. The current trial sought compare FFR-guided angiography-guided for lesions among MI disease. Methods results Patients disease who had undergone successful the infarct-related were randomly...
Background Coronary microvascular dysfunction (CMD) has been considered as a possible cause of cardiac diastolic dysfunction. The current study evaluated the association between and CMD, their prognostic implications in patients without significant left ventricular systolic epicardial coronary stenosis. Methods Results A total 330 (ejection fraction ≥50%) stenosis (fractional flow reserve >0.80) were analyzed. Cardiac was defined by echocardiographic parameters (early transmitral...
Background Recently, diastolic stress testing and invasive hemodynamic measurements have been emphasized for diagnosis of heart failure with preserved ejection fraction (HFpEF) because when determined using noninvasive parameters it can fall into a nondiagnostic intermediate range. The current study evaluated the discriminative prognostic roles measured left ventricular end‐diastolic pressure in population suspected HFpEF, particularly patients Heart Failure Association Pre‐test Assessment,...
Background: Coronary microvascular dysfunction is a clinically significant component of ischemic heart disease. There can be heterogenous patterns coronary defined by invasive physiologic indexes such as flow reserve (CFR) and index microcirculatory resistance (IMR). We sought to compare the prognosis according different CFR IMR. Methods: The current study included 375 consecutive patients undergoing assessment for suspected stable disease intermediate but functionally nonsignificant...
There are limited clinical data on drug-coated balloon (DCB)-based percutaneous coronary intervention (PCI) compared with drug-eluting stent (DES)-only PCI in patients complex artery lesions.
Importance There have been heterogeneous results related to sex differences in prognosis after percutaneous coronary artery intervention (PCI) for complex lesions. Objective To evaluate potential outcomes with intravascular imaging–guided PCI of lesions between women and men. Design, Setting, Participants This prespecified substudy evaluates the interaction investigator-initiated, open-label, multicenter RENOVATE-COMPLEX-PCI randomized clinical trial, which demonstrated superiority compared...
Although potent P2Y12 inhibitors, such as ticagrelor and prasugrel, are standard treatment in patients with acute myocardial infarction (AMI), evidence for their efficacy safety compared clopidogrel is limited AMI complicated by cardiogenic shock. Among 28,949 from the nationwide pooled registry of KAMIR-NIH KAMIR-V, a total 1482 (5.1%) shock who underwent percutaneous coronary intervention culprit vessel were selected. Primary outcome was major adverse cardiovascular event (MACE, composite...
Little is known about the characteristics of arterial stiffness in heart failure (HF). This study was performed to compare degree and its association with left ventricular (LV) diastolic function among three groups: control subjects, patients HF reduced ejection fraction (HFrEF), preserved (HFpEF).A total 83 HFrEF, 68 HFpEF, 84 subjects were analyzed. All had a history hospitalization for treatment. Brachial-ankle pulse wave velocity (baPWV) measurement transthoracic echocardiography at same...
A 31-year-old male visited a local hospital due to sudden-onset severe abdominal pain. Abdominal computed tomography revealed solid cystic mass with size of approximately 12 cm and exhibiting both hemorrhage fluid collection in the pelvic cavity. Emergency angiography embolization were performed, large hepatic tumor was subsequently surgically resected. The cells stained positive for human melanoma black-45 smooth-muscle actin, pathologic diagnosis angiomyolipoma. This case report also...
Both coronary flow reserve (CFR) and chronic kidney disease (CKD) are known to be associated with adverse cardiac events. However, it is unclear how these prognostic factors interrelated. This study evaluated the association between intracoronary physiologic indexes CKD their implications.A total of 351 patients without left ventricular systolic dysfunction (ejection fraction ≥ 40%) not on dialysis whose revascularization was deferred based fractional (FFR) > 0.80 were analyzed. Depressed...
As patients with chronic kidney disease (CKD) are more likely to have complex coronary lesions, intravascular imaging guidance in percutaneous intervention (PCI) for this population could be potentially beneficial.To investigate whether the outcomes of imaging-guided procedural optimization would different according presence CKD.This was a prespecified substudy RENOVATE-COMPLEX-PCI, recently published multicenter randomized clinical trial Korea studying benefits lesions. Patients or without...
BACKGROUND: The Murray law–based quantitative flow ratio (μFR) is an emerging technique that requires only 1 projection of coronary angiography with similar accuracy to (QFR). However, it has not been validated for the evaluation noninfarct-related artery (non-IRA) in acute myocardial infarction (AMI) settings. Therefore, our study aimed evaluate diagnostic μFR and safety deferring non-IRA lesions >0.80 setting AMI. METHODS: QFR were analyzed patients AMI enrolled FRAME-AMI trial...
The impact of socioeconomic status (SES) on arterial stiffness remains unclear. This study aimed to explore the association between both personal and household income, as well education level, estimated pulse wave velocity (ePWV).
Background Intracoronary physiologic indexes such as coronary flow reserve (CFR) and left ventricular ejection fraction (LVEF) have been regarded prognostic indicators in patients with artery disease. The current study evaluated the association between intracoronary LVEF their differential implications Methods Results A total of 1889 2492 vessels available CFR were selected from an international multicenter prospective registry. Baseline measured by thermodilution or Doppler methods was...
The prognostic value of changes in arterial stiffness has not been well evaluated. This study was conducted to investigate whether the change one month after percutaneous coronary intervention (PCI) affects long-term cardiovascular prognosis.A total 405 patients (mean age, 62.0 ± 11.0 years; female sex, 27.7%) who underwent PCI with drug-eluting stent (DES) implantation prospectively enrolled. measurement brachial-ankle pulse wave velocity (baPWV) taken all patient at time admission for...
The correlation between body fat parameters and arterial stiffness is still under debate. This study aimed to examine the associations of mass index (BMI) waist circumference (WC) with estimated pulse wave velocity (ePWV). We utilized data from 14,228 subjects (mean age 53.4 ± 16.8 years; 56.9% were female) Korean National Health Nutrition Examination Survey. ePWV was calculated using a formula based on blood pressure. Simple linear analyses revealed significant both BMI (r = 0.098; p <...
Abstract Data on the relationship between arterial pulsatile hemodynamics and aortic root geometry, using invasive hemodynamic measurement, has been scarce. Thus, this study aimed to assess invasively measured pulse pressure (aPP) diameter of ascending aorta (AoD). We analyzed 665 subjects (64.3 ± 11.0 years; 34.6% female) who underwent elective coronary angiography (ICA) for evaluation artery disease. Transthoracic echocardiography was performed same day, AoD at level 1 cm above sinotubular...
To make good use of the prognostic value arterial stiffness, it is important to identify population with greatest benefit. In this study, we compared brachial-ankle pulse wave velocity (baPWV) according various clinical characteristics.A total 10,597 subjects who underwent baPWV measurement (mean age, 61.4 ± 9.5 years; female proportion, 42.5%) were retrospectively analyzed. Major adverse cardiovascular events (MACEs), defined as a composite cardiac death, non-fatal myocardial infarction,...
65-year-old woman was admitted to our hospital with acute decompensated heart failure reduced left ventricular ejection fraction and severe mitral regurgitation. Electrocardiography revealed a typical bundle branch block atrial fibrillation. Her condition deteriorated despite administering high-doses of inotropes vasopressors. Pending decision therapy, venoarterial extracorporeal membrane oxygenation (ECMO) performed when the patient underwent cardiogenic shock. Although hemodynamic status...