A5091114655- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Acute Myocardial Infarction Research
- Cardiovascular Disease and Adiposity
- Cardiovascular Function and Risk Factors
- Advanced MRI Techniques and Applications
- Venous Thromboembolism Diagnosis and Management
- Cardiac Valve Diseases and Treatments
- Advanced X-ray and CT Imaging
- Sleep and related disorders
- Cerebrovascular and Carotid Artery Diseases
- Radiomics and Machine Learning in Medical Imaging
- Blood Pressure and Hypertension Studies
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Hearing Loss and Rehabilitation
- COVID-19 Clinical Research Studies
- Phonocardiography and Auscultation Techniques
- Lipoproteins and Cardiovascular Health
- Sleep and Work-Related Fatigue
- Cardiac, Anesthesia and Surgical Outcomes
- COVID-19 and healthcare impacts
- Cardiovascular Health and Disease Prevention
- Hemodynamic Monitoring and Therapy
- Atherosclerosis and Cardiovascular Diseases
- Traditional Chinese Medicine Analysis
Fudan University
2019-2025
Zhongshan Hospital
2019-2025
National Clinical Research Center for Digestive Diseases
2021-2025
Chinese Academy of Medical Sciences & Peking Union Medical College
2025
Shanghai Clinical Research Center
2023-2025
National Clinical Research
2024
Sun Yat-sen University
2019-2023
The First Affiliated Hospital, Sun Yat-sen University
2019-2023
Samsung Medical Center
2021
Shanghai Tenth People's Hospital
2013-2020
SARS-CoV-2 infection was associated with coronary atherosclerotic plaque progression, as assessed by CT angiography, and worse cardiovascular outcomes.
Background: Angiography-derived index of microcirculatory resistance (angio-IMR) is an emerging pressure-wire-free to assess coronary microvascular function, but its diagnostic and prognostic value remains be elucidated. Methods Results: The study population consisted three independent cohorts. internal cohort enrolled 53 patients with available hyperemic (HMR) calculated from myocardial blood flow pressure. external included 35 ischemia no obstructive artery disease (INOCA) 45 controls. 138...
Background: Lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular events. This study evaluated the relationship between Lp(a) and high-risk attributes by coronary computed tomography angiography as well their prognostic value. Methods: from 377 consecutive patients at Zhongshan Hospital (Shanghai, China) were evaluated. High-risk defined morphological (low attenuation plaque, positive remodeling, napkin-ring sign, spotty calcification, minimum lumen area <4 mm 2 , or plaque burden...
The cohort study aimed to assess the association of nighttime sleep duration and change in with chronic kidney disease (CKD) whether between CKD differed by daytime napping.This included 11,677 individuals from China Health Retirement Longitudinal Study (CHARLS) used data 2011 baseline survey four follow-up waves. Nighttime was divided into three groups: short (<7 h per night), optimal (7-9 h), long (>9 h). Daytime napping two no nap a nap. We Cox proportional hazards model examine...
Background Coronary diffuse disease associates with poor outcomes, but little is known about its role after percutaneous coronary intervention (PCI). We aimed to investigate the prognostic implication of pre‐PCI focal or patterns combined post‐PCI quantitative flow ratio (QFR). Methods and Results Pre‐PCI QFR derived pullback pressure gradient (PPG) (QFR‐PPG) was measured assess physiological for 1685 included vessels; vessels were classified according dichotomous QFR‐PPG QFR....
Intravascular ultrasound (IVUS) imaging allows direct visualization of the coronary vessel wall and is suitable for assessing atherosclerosis degree stenosis. Accurate segmentation lumen median-adventitia (MA) measurements from IVUS are essential such a successful clinical evaluation. However, current automated by commercial software relies on manual corrections, which time-consuming user-dependent. We aim to develop deep learning-based method using an encoder-decoder architecture...
Dilated cardiomyopathy (DCM), the most common form of primary myocardial disease, is an important cause sudden cardiac death and heart failure leading indication for transplantation in children adults worldwide. Recent studies have revealed a strong genetic basis idiopathic DCM, with many distinct genes causally implicated. Nevertheless, DCM genetically heterogeneous disorder determinants underlying substantial proportion patients remain unclear. In this study, whole coding exons flanking...
Transradial access is an attractive approach for angiography or percutaneous coronary intervention. Different devices have been used to apply pressure locally at the site of arterial entry achieving hemostasis. The aim this study was evaluate effect 2 different hemostatic on radial artery outcomes after transradial intervention.This included 600 patients who had undergone intervention were randomized into groups procedure: 300 treated with a compression device (TR Band, Terumo Medical,...
Atherosclerotic cardiovascular disease (ASCVD) remains a major cause of morbidity and mortality globally. Traditional risk factors such as hypertension, smoking, hypercholesterolemia are essential in prevention, but fail to fully capture the complexity coronary artery (CAD) progression. This opinion advocates for shifting from factor-based models an atherosclerosis-centered approach, focusing on plaque assessment. Recent studies show that computed tomography angiography (CTA) improves...
While coronary computed tomography angiography (CCTA) enables the evaluation of anatomic and hemodynamic plaque characteristics artery disease (CAD), clinical roles these are not clear. We sought to evaluate prognostic implications CCTA-derived in prediction subsequent events.The study cohort consisted 158 patients who underwent CCTA with suspected CAD within 6-36 months before percutaneous intervention (PCI) for acute myocardial infarction (MI) or unstable angina age-/sex-matched 62 without...
BACKGROUND: Sex-specific differences in coronary phenotypes response to stress have not been elucidated. This study investigated the sex-specific computed tomography angiography-assessed mental stress. METHODS: retrospective included patients with artery disease and without cancer who underwent resting 18 F-fluorodexoyglucose positron emission tomography/computed angiography within 3 months. F-flourodeoxyglucose amygdalar uptake, an imaging biomarker of stress-related neural activity,...
Abstract Aims Peri-procedural myocardial infarction (PMI) after percutaneous coronary intervention (PCI) has been shown to be associated with worse clinical outcomes. We aimed investigate the value of plaque characteristics and physiologic disease patterns (focal vs. diffuse) assessed by computed tomography angiography (CTA) in predicting PMI adverse events. Methods results Three hundred fifty-nine patients normal pre-PCI high-sensitivity cardiac troponin T (hs-cTnT) underwent CTA before PCI...