- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Neurosurgical Procedures and Complications
- Moyamoya disease diagnosis and treatment
- Spinal Fractures and Fixation Techniques
- Spine and Intervertebral Disc Pathology
- Cerebrospinal fluid and hydrocephalus
- Neurological Complications and Syndromes
- Intracerebral and Subarachnoid Hemorrhage Research
- Pelvic and Acetabular Injuries
- Cervical and Thoracic Myelopathy
- Thermal Regulation in Medicine
- Venous Thromboembolism Diagnosis and Management
- Vascular Malformations Diagnosis and Treatment
- Spinal Hematomas and Complications
- Stroke Rehabilitation and Recovery
- Spinal Cord Injury Research
- Pituitary Gland Disorders and Treatments
- MRI in cancer diagnosis
- Glioma Diagnosis and Treatment
- Child Abuse and Related Trauma
- Cardiovascular Health and Disease Prevention
- Meningioma and schwannoma management
Catholic University of Korea
2014-2024
Eunpyeong Hospital
2023
Seoul St. Mary's Hospital
2020
Uijeongbu St. Mary's Hospital
2010-2019
St. Paul's Hospital
2017
Catholic University of America
1998-2014
Kangwon National University
2011
Seoul National University
2011
Sungkyunkwan University
2011
Norsk Hydro (Germany)
2011
The management of massive brain swelling remains an unsolved problem in neurosurgery. Despite newly developed medical and pharmacological therapy, the rates mortality morbidity caused by remain high. According to many recent reports, surgical decompression with dural expansion is superior patients swelling. To show quantitative effect decompressive surgery on intracranial pressure (ICP), authors performed a ventricular puncture measured ICP continuously during postoperative period.Twenty who...
The present study analyzed the risk factors, prevalence and clinical results following revision surgery for adjacent segment degeneration (ASD) in patients who had undergone lumbar fusion.Over an 8-year period, we performed posterior fusion 81 patients. Patients were followed a minimum of 2 years (mean 5.5 years). During that time, 9 required due to ASD development. Four underwent autogenous posterolateral arthrodesis extended transpedicle screw fixation, 4 decompressive laminectomy...
Object The various terms used to describe subdural fluid collection—“external hydrocephalus,” “subdural hygroma,” effusion,” “benign collection,” and “extraventricular obstructive hydrocephalus”—reflect the confusion surrounding diagnoses of these diseases. Differentiating external hydrocephalus from simple hygroma may be difficult, but former appears a distinct clinical entity separate latter. In this report, authors present diagnostic method for differentiating hygroma, based on their...
The effects on neural proliferation and differentiation of stem cells (NSC) basic fibroblast growth factor-2 (bFGF), insulin factor-I (IGF-I), brain-derived neurotrophic factor (BDNF), nerve (NGF) were assessed. Also, following combinations various factors investigated : bFGF+IGF-I, bFGF+BDNF, bFGF+NGF, IGF-I+BDNF, IGF-I+NGF, BDNF+NGF.Isolated NSC Fisher 344 rats cultured with individual factors, no (control) for 14 days. A proportion neurons was analyzed using beta-tubulin III NeuN as...
In the present study, we evaluated effect, safety and radiological outcomes of cervical hybrid surgery (cervical disc prosthesis replacement at one level, interbody fusion other level) on multilevel degenerative disease (DDD).Fifty-one patients (mean age 46.7 years) with symptomatic spondylosis were treated using (HS). Clinical [neck disability index (NDI) Visual Analogue Scale (VAS) score] radiologic [range motion (ROM) for spine, adjacent segment arthroplasty level] routine postoperative...
Moyamoya disease is characterized by progressive cerebrovascular occlusion at the peripheral internal carotid artery and development of abnormal collateral circulation cerebral basal region. Although thrombogenesis, inflammation autoimmune process might be involved in etiology, genetic pathogenesis still unknown. To evaluate association with HLA alleles Korean population, we investigated class I II 28 patients 198 unrelated healthy controls. The frequency HLA-B35 allele was significantly...
<h3>BACKGROUND AND PURPOSE:</h3> Various modifications of detachable coils have been attempted to reduce recurrence rates in aneurysmal coil embolization and HydroSoft is one them. The authors report their experience using the treatment cerebral aneurysms. <h3>MATERIALS METHODS:</h3> present study a prospective multicenter observational series 127 aneurysms 120 patients treated with coils. <h3>RESULTS:</h3> Ten centers participated this study, there were 92 (72%) unruptured 35 ruptured...
Our objective was a retrospective assessment of the management modalities that provided most beneficial treatment in hemorrhagic moyamoya disease during last 13 years at our institution. The clinical results 44 patients with were investigated, comparing revascularization surgery (direct, indirect, and combined bypass) or conservative treatment. Angiographic features, rebleeding, outcome investigated. Six 35 (17.1%) experienced as did 4 9 (44.4%) However, who underwent bypass had lower chance...
Magnesium ions have been shown to be a promising treatment for brain lesions caused by traumatic injury (TBI), as well the associated acute neurodegeneration and progressive functional deficits. This study investigated effects of magnesium on expression cell death/survival related proteins following TBI. Male Sprague-Dawley (SD) rats (n = 66, 280-320 g body weight) were subjected sham surgery alone 14), or followed lateral fluid percussion moderate severity 52, 2.4-2.7 atm). The injured...
Craniovertebral junction (CVJ) consists of the occipital bone that surrounds foramen magnum, atlas and axis vertebrae. The mortality morbidity is high for irreducible CVJ lesion with cervico-medullary compression. In a clinical retrospective study, authors reviewed radiographic results occipitocervical fusion using various methods in 32 patients instability.Thirty-two lesions (18 male 14 female) were treated our department 12 years. Instability resulted from trauma (14 cases), rheumatoid...
✓ Neurocutaneous melanosis (NCM) associated with Dandy–Walker malformation is a very rare congenital neurodysplasia the same origin. Primary intracranial melanocytic and dermoid tumors are also benign lesions that usually arise from leptomeninges formed by inclusion of cutaneous ectoderm at time neural tube closure. The authors describe patient coexisting meningeal melanocytoma, NCM malformation, intraventricular tumor.
This study investigated the effect of bone marrow mesenchymal stem cells (BMSCs) on motor pathway in transient ischemic rat brain that were transplanted through carotid artery, measuring motor-evoked potential (MEP) four limbs muscle and atlantooccipital membrane, which was elicited after monopolar bipolar transcortical stimulation. After stimulation, latency MEP significantly prolonged, amplitude less reduced BMSC group comparison with control (P < .05). MEPs induced by stimulation left...
Background. Primary cutaneous lymphoma (PCL) is an extranodal non‐Hodgkin with primary involvement of the skin. Epidemiological data on PCLs according to World Health Organization/European Organization for Research and Treatment Cancer classification (WHO‐EORTC) has not been investigated in Korea date. Aim. To evaluate demographic characteristics, clinical histological features, survival patients PCL WHO‐EORTC classification. Methods. In total, 93 were retrospectively identified from...
Castleman's disease is a rare of the lymph nodes and related tissues, presenting as angiofollicular or giant node hyperplasia. Although various skin manifestations have been reported to occur in disease, comprehensive study cutaneous disorders lacking. Therefore, aim this was investigate disease-associated disorders. The medical records 57 patients with who visited our hospitals from January 2007 May 2018 were analysed retrospectively. Patients classified according presence involvement....
Stroke caused from large vessel occlusion (LVO) has emerged as the most common stroke subtype worldwide. Intravenous tissue plasminogen activator administration (IV-tPA) and additional intraarterial thrombectomy (IA-Tx) is regarded standard treatment. In this study, authors try to find early recanalization rate of IV-tPA in LVO patients.Total 300 patients undertook IA-Tx with confirmed anterior circulation LVO, were analyzed retrospectively. Brain computed tomography angiography (CTA) was...