Wonjung Hwang

ORCID: 0000-0003-2820-0322
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About
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Research Areas
  • Anesthesia and Pain Management
  • Cardiac, Anesthesia and Surgical Outcomes
  • Airway Management and Intubation Techniques
  • Cancer, Stress, Anesthesia, and Immune Response
  • Respiratory Support and Mechanisms
  • Anesthesia and Sedative Agents
  • Anesthesia and Neurotoxicity Research
  • Hemodynamic Monitoring and Therapy
  • Neuropeptides and Animal Physiology
  • Pulmonary Hypertension Research and Treatments
  • Nanoplatforms for cancer theranostics
  • Nausea and vomiting management
  • Inhalation and Respiratory Drug Delivery
  • Pain Management and Opioid Use
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Enhanced Recovery After Surgery
  • Pediatric Pain Management Techniques
  • Pleural and Pulmonary Diseases
  • Inflammatory Biomarkers in Disease Prognosis
  • Intraoperative Neuromonitoring and Anesthetic Effects
  • Head and Neck Cancer Studies
  • Liver Disease and Transplantation
  • Central Venous Catheters and Hemodialysis
  • Ultrasound in Clinical Applications
  • Intensive Care Unit Cognitive Disorders

Catholic University of Korea
2014-2025

Seoul St. Mary's Hospital
2015-2025

University of California, San Francisco
2021

Korea National Institute of Health
2020

University of Minnesota System
2019

University of Pennsylvania
2011

Total intravenous anesthesia (TIVA) is used widely in spinal surgery because inhalational anesthetics are known to decrease the amplitude of motor evoked potentials. Presently, dexmedetomidine as an adjuvant for propofol-based TIVA. We compared effects remifentanil and on pain intensity well analgesic requirements after post-anesthesia care unit (PACU) discharge patients undergoing surgery. Forty scheduled posterior lumbar interbody fusion (PLIF) under general were enrolled. Anesthesia was...

10.1186/s12871-015-0004-1 article EN cc-by BMC Anesthesiology 2015-02-24

Airway driving pressure, easily measured as plateau pressure minus PEEP, is a surrogate for alveolar stress and strain. However, the effect of its targeted reduction remains unclear.In this multicentre trial, patients undergoing lung resection surgery were randomised to either group (n=650) receiving an recruitment/individualised PEEP deliver lowest or conventional protective ventilation with fixed 5 cm H2O. The primary outcome was composite pulmonary complications within 7 days...

10.1016/j.bja.2022.06.037 article EN cc-by British Journal of Anaesthesia 2022-08-20

Background: Thoracic surgery often causes severe postoperative pain, even when minimally invasive techniques are employed. Effective pain management is essential for optimizing recovery and improving patients’ quality of life. Traditional opioid-based strategies effectively alleviate but lead to significant adverse effects. Multimodal analgesia (MMA) a comprehensive approach combining pharmacologic non-pharmacologic methods. This strategy aims minimize opioid use, target multiple pathways,...

10.5124/jkma.2025.68.1.29 article EN cc-by-nc Journal of Korean Medical Association 2025-01-10

Abstract Background Nefopam and propacetamol are the most commonly used analgesics in postoperative multimodal analgesic regimens. Distinct mechanisms involved each drug’s anti-nociceptive effects. No studies have compared pain relief efficacy between two drugs patients undergoing transplantation surgery. Here, we investigated whether administration of nefopam or to healthy living kidney donors who underwent rectus sheath block (RSB) for parietal could reduce subsequent opioid dose necessary...

10.1186/s12871-024-02607-5 article EN cc-by BMC Anesthesiology 2024-07-02

Opioids effectively manage perioperative pain but have numerous adverse effects. Opioid-free anesthesia (OFA) eliminates intraoperative opioid use; however, evidence for its use in video-assisted thoracoscopic surgery (VATS) is limited. This study assessed the effect of OFA using ketamine VATS patients compared to opioid-sparing (OSA). A total 91 undergoing lobectomy or segmentectomy were randomized either group (ketamine) OSA (remifentanil). The primary outcome was quality recovery (QoR) on...

10.3390/jpm14080881 article EN Journal of Personalized Medicine 2024-08-21

Non-intubated thoracoscopic surgery is an evolving form of minimally-invasive thoracic surgery. We commenced performing non-intubated at our center in August 2016. would like to report initial experience, over a period 1 year, with this procedure.From 2016 2017, was performed series consecutive patients who underwent those did not meet any the following exclusion criteria: body mass index (BMI) >30, expected difficult airway, extensive pleural adhesion, severe cardiopulmonary dysfunction,...

10.21037/jtd.2018.05.147 article EN cc-by-nc-nd Journal of Thoracic Disease 2018-06-01

Complete drainage of the pulmonary veins into right heart is one rarest and most severe congenital cardiac anomalies. The X-ray studies may suggest this diagnosis if enter either coronary sinus or inferior vena cava. In case reported, catheterization angiocardiography were used persisent left superior cava partial direct auricle was made.

10.1161/01.cir.2.4.553 article EN Circulation 1950-10-01

Background. Surgical trauma elicits inflammatory responses, including the secretion of cytokines. Recent studies demonstrated that beta-blockers could reduce expression cytokines after injury. We therefore tested effects different doses intraoperative esmolol on response surgery. Methods. Patients undergoing laparoscopic gastrectomy were randomly separated into 1 3 groups: saline, clinical dose, and subclinical dose groups. The levels interleukin (IL)-6, IL-4, IL-10 quantified by sandwich...

10.1177/1553350614532534 article EN Surgical Innovation 2014-05-06

Postoperative delirium (POD) is a common but serious complication after cardiac surgery and associated with various short- long-term outcomes. In this study, we investigated the effects of intraoperative glycemic variability (GV) other variables on POD surgery.A retrospective single-center cohort analysis was conducted using data from electronic medical record 2018 to 2020. A total 705 patients undergoing coronary artery bypass graft and/or valve surgery, aortic replacement were included in...

10.2147/cia.s338712 article EN cc-by-nc Clinical Interventions in Aging 2022-02-01

Hypoxemia can occur during one-lung ventilation (OLV) in thoracic surgery, leading to perioperative complications. Inhaled iloprost is a selective pulmonary vasodilator with efficacy patients hypertension. The purpose of this study was evaluate the effects off-label inhaled on oxygenation OLV undergoing lung surgery. Seventy-two who were scheduled for elective video-assisted thoracoscopic lobectomy assigned receive an nebulizer distilled water (control group), 10 μg (IL10 or 20 (IL20 group)....

10.3390/jcm8070982 article EN Journal of Clinical Medicine 2019-07-05

Abstract Background Surgery is the primary treatment for non-small cell lung cancer (NSCLC), but microscopic residual disease may be unavoidable. Preclinical studies have shown that volatile anesthetics might suppress host immunity and promote a pro-malignant environment supports proliferation, migration, angiogenesis, whereas propofol preserve cell-mediated inhibit tumor angiogenesis. However, clinical evidence propofol-based total intravenous anesthesia (TIVA) can reduce recurrence after...

10.1186/s13741-024-00436-1 article EN cc-by Perioperative Medicine 2024-07-23

The inflammatory response after surgery is associated with patient prognosis. Patients who undergo thoracic exhibit a profound systemic due to the surgical procedures used and application of one-lung ventilation. aim this study was compare perioperative changes in patients intubated non-intubated for primary lung cancer resection.This prospective randomized controlled included forty underwent resection stage I non-small-cell cancer. Blood samples cytokine analysis were collected just before...

10.1093/icvts/ivaa265 article EN Interactive Cardiovascular and Thoracic Surgery 2020-10-28

Background: Propofol-based total intravenous anesthesia (TIVA) improves long-term outcomes after cancer surgery compared with inhalation anesthesia. However, its effect on patients undergoing non-small cell lung (NSCLC) remains unclear. We aimed to compare the oncological of TIVA and curative resection early-stage NSCLC. Methods: analyzed medical records diagnosed stage I or II NSCLC who underwent at a tertiary university hospital between January 2010 December 2017. The primary were...

10.4097/kja.22584 article EN cc-by-nc Korean journal of anesthesiology 2022-12-29

Thyroid storm is a critical complication of molar pregnancy. However, early diagnosis it difficult because rare and usually presents nonspecific findings. In this case report, we present woman with pregnancy who had persistent tachycardia hypertension. She was diagnosed initially preeclampsia sepsis as complications During dilation curettage under general anesthesia sevoflurane remifentanil, hypertension remained even continuous infusion labetalol. The patient subsequently thyroid associated...

10.4097/kjae.2014.67.3.205 article EN cc-by-nc Korean journal of anesthesiology 2014-01-01

Background/Objectives: Preoperative fasting guidelines traditionally aim to reduce pulmonary aspiration risk. However, concerns over the adverse effects of prolonged have led exploring alternatives. This study aimed investigate impact preoperative clear liquid intake on postoperative outcomes in children undergoing minimally invasive repair pectus excavatum (MIRPE). Methods: A prospective randomized controlled was conducted aged 3–6 years scheduled for elective MIRPE. Patients were into...

10.3390/jcm13123593 article EN Journal of Clinical Medicine 2024-06-19
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