A5068363257- Anesthesia and Pain Management
- Anesthesia and Sedative Agents
- Airway Management and Intubation Techniques
- Nausea and vomiting management
- Respiratory Support and Mechanisms
- Cardiac, Anesthesia and Surgical Outcomes
- Hemodynamic Monitoring and Therapy
- Cardiac Arrest and Resuscitation
- Spine and Intervertebral Disc Pathology
- Intensive Care Unit Cognitive Disorders
- Anesthesia and Neurotoxicity Research
- Cancer, Stress, Anesthesia, and Immune Response
- Lung Cancer Diagnosis and Treatment
- Ultrasound in Clinical Applications
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Tracheal and airway disorders
- Food Quality and Safety Studies
- Pleural and Pulmonary Diseases
- Radiation Effects and Dosimetry
- Pain Management and Opioid Use
- Pain Mechanisms and Treatments
- Inflammatory mediators and NSAID effects
- Esophageal and GI Pathology
- Aortic aneurysm repair treatments
- Organ Transplantation Techniques and Outcomes
Samsung Medical Center
2016-2025
Sungkyunkwan University
2016-2025
Hallym University
2008-2023
Seoul National University Bundang Hospital
2023
Pain and Rehabilitation Medicine
2022
Korea Research Institute of Bioscience and Biotechnology
2003-2021
Kangwon National University
2019
Novem (Netherlands)
2019
Jeju National University
2016
Jacobson Holman (United States)
2015
Driving pressure (plateau minus end-expiratory airway pressure) is a target in patients with acute respiratory distress syndrome, and proposed as during general anesthesia for normal lungs. It has not been reported thoracic where isolated, inflated lungs may be especially at risk.In double-blinded, randomized trial (292 patients), minimized driving compared standard protective ventilation was associated less postoperative pneumonia or syndrome.Recently, several retrospective studies have...
To propose a modified angiographic classification for peripheral arteriovenous malformations (AVMs) and to determine its value assessing therapeutic outcomes approaches ethanol embolization of AVMs in the body extremities.AVMs trunk extremities were categorized according morphology nidus: type I (arteriovenous fistulae), II (arteriolovenous IIIa (arteriolovenulous fistulae with non-dilated fistula), IIIb dilated fistula). Sixty-six patients (41 women; mean age 28.3 years, range 5-53)...
Phenformin (phenethylbiguanide; an anti-diabetic agent) plus oxamate [lactate dehydrogenase (LDH) inhibitor] was tested as a potential anti-cancer therapeutic combination. In in vitro studies, phenformin more potent than metformin, another biguanide, recently recognized to have effects, promoting cancer cell death the range of 25 times 15 million various lines. The effect related complex I inhibition mitochondria and subsequent overproduction reactive oxygen species (ROS). Addition inhibited...
Summary We evaluated the effect of pre‐operative serratus anterior plane block on postoperative pain and opioid consumption after thoracoscopic surgery. randomly allocated 89 participants to with 30 ml ropivacaine 0.375% (n = 44), or no without placebo sham procedure 45). analysed results from 42 in each group. Serratus reduced mean (SD) remifentanil dose during surgery, 0.12 (0.06) mg.h −1 vs. 0.16 , p 0.016, fentanyl first 24 hours, 3.8 (1.9) μg.kg 5.7 (1.6) 0.000004. Block also worst...
Airway driving pressure, easily measured as plateau pressure minus PEEP, is a surrogate for alveolar stress and strain. However, the effect of its targeted reduction remains unclear.In this multicentre trial, patients undergoing lung resection surgery were randomised to either group (n=650) receiving an recruitment/individualised PEEP deliver lowest or conventional protective ventilation with fixed 5 cm H2O. The primary outcome was composite pulmonary complications within 7 days...
BackgroundEndoscopic sinus surgery (ESS) is often affected by intra-nasal bleeding, which can be influenced various anaesthetics and preoperative conditions. This study compared the surgical condition amount of bleeding between patients given sevoflurane/remifentanil (SR) propofol/remifentanil (PR) anaesthesia.MethodsASA I or II undergoing ESS were randomly assigned to group SR (n=20) PR (n=20). The extent lesion was classified as high (>12) low Lund–Mackay (LM) (≤12) scores according...
Fluid is restricted in thoracic surgery to reduce acute lung injury, and hydroxyethyl starches (HES) are often administered fluid amount. This strategy may contribute the development of kidney injury (AKI). We evaluated incidence, risk factors, prognosis AKI surgery. especially focused on whether restriction/HES administration increased AKI.This a retrospective study patients undergoing tertiary care academic center. Postoperative was diagnosed within 72 hours after based Acute Kidney Injury...
The healthy condition of living donors makes their tolerance to pain particularly low, and clinicians are often challenged come up with an analgesic technique that is effective yet ensures donor safety. This study compared, in right hepatectomy, the efficacy safety preoperative intrathecal morphine (ITM) combined intravenous patient-controlled analgesia (IV-PCA) IV-PCA alone. Forty adult patients were randomly allocated into 2 groups: ITM+IV-PCA group (n = 20) IV-PCA-only 20). Patients...
BACKGROUND: Stroke volume variation (SVV) and pulse pressure (PPV) are used as indicators of fluid responsiveness, but little is known about the usefulness these dynamic preload in thoracic surgery, which involves an open cavity 1-lung ventilation (OLV). Therefore, we investigated whether SVV PPV could predict thresholds parameters should be adjusted for surgery. METHODS: This was a prospective, controlled study conducted tertiary care center. Eighty patients scheduled elective lobectomy...
In Brief BACKGROUND: There have been inconsistent reports on whether opioids promote or inhibit lung cancer growth. this study, we suggest that opioid growth factor receptor (OGFR), a negative regulator of cell proliferation, is binding site morphine and involved in subsequent morphine-induced suppression. METHODS: The expression distribution OGFR human tissues lines were assessed with immunohistochemistry real-time reverse transcription polymerase chain reaction. line, H1975...
BACKGROUND: Postoperative analgesic methods are suggested to have an impact on long-term prognosis after cancer surgery through opioid-induced immune suppression. We hypothesized that regional analgesia reduces the systemic opioid requirement would be related lower recurrence and higher overall survival compared intravenous patient-controlled (PCA) for lung surgery. METHODS: Records all patients who underwent open thoracotomy curative resection of primary between 2009 2013 in a tertiary care...
Background Despite previous reports suggesting that pressure support ventilation facilitates weaning from mechanical in the intensive care unit, few studies have assessed its effects on recovery anesthesia. The authors hypothesized during emergence anesthesia reduces postoperative atelectasis patients undergoing laparoscopic surgery using Trendelenburg position. Methods In this randomized controlled double-blinded trial, adult colectomy or robot-assisted prostatectomy were assigned to either...
The use of epidural catheters has been a subject active debate in living liver donors because the possible postoperative coagulation derangement and subsequent risk hematoma. aim this study was to evaluate safety relation changes profile based on review previously published literature results our 360 donors. In both cases, platelet count, prothrombin time (PT), activated partial thromboplastin (aPTT) cases heparin administration showed significant (P < 0.05), especially after right...
Summary Tracheal intubations with the Airway Scope or Clarus Video System, a new rigid fibrescope, were compared in 140 patients whose necks immobilised by cervical collars. The time for intubation, success rate, number of attempts and optimisation manoeuvres assessed. Mean (SD) intubation was longer (30.4 (16.5) s) than System (18.9 (15.2) s; p = 0.003) median (IQR [range]) also marginally different; 0 (0–1 [0–2]) Scope, (0–0 System; 0.004. tracheas 67 (95.7%) 66 (94.3%) successfully...
Postoperative analgesia and care for living liver donors have become particular interests clinicians as the use of donor transplantation has increased. Local anesthetic-based been known to provide effective pain control. In this prospective, randomized study, we compared postoperative analgesic efficacy local (PainBuster) with opioid-based [intrathecal morphine (ITM) intravenous (IV) fentanyl] in donors. Forty adult were randomly allocated 1 2 groups: an ITM/IV fentanyl group (n = 21) a...