A5043552754- Organ Transplantation Techniques and Outcomes
- Liver Disease and Transplantation
- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease Diagnosis and Treatment
- Renal Transplantation Outcomes and Treatments
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Hepatitis B Virus Studies
- Organ Donation and Transplantation
- Hepatitis C virus research
- Transplantation: Methods and Outcomes
- Pancreatic and Hepatic Oncology Research
- Cancer, Lipids, and Metabolism
- Gallbladder and Bile Duct Disorders
- Cytomegalovirus and herpesvirus research
- Viral-associated cancers and disorders
- Pancreatic function and diabetes
- Neurological Complications and Syndromes
- Polyomavirus and related diseases
- Immune Cell Function and Interaction
- Liver physiology and pathology
- Cancer, Hypoxia, and Metabolism
- Hematopoietic Stem Cell Transplantation
- Herpesvirus Infections and Treatments
- Pediatric Hepatobiliary Diseases and Treatments
- Congenital Anomalies and Fetal Surgery
Samsung Medical Center
2016-2025
Sungkyunkwan University
2015-2024
Samsung Changwon Hospital
2023-2024
Samsung (South Korea)
2023-2024
Changwon National University
2023-2024
ORCID
2023
Yahoo (United Kingdom)
2023
Association of British Orchestras
2023
Dioxide Materials (United States)
2023
Total (Germany)
2023
The outcome after living donor renal transplantation is superior to that for deceased transplantation, but the results are not uniformly successful. factors responsible variable have been well defined.UK Transplant Registry data were analyzed determine outcomes of 3142 first adult kidney transplants from donors (71% genetically related and 29% unrelated) performed between 2000 2007 inclusive. Kaplan-Meier survival estimates determined, might be associated with graft patient using Cox...
To compare the efficacy of radiofrequency ablation (RFA) and surgical resection in a group patients with Child-Pugh score 5 single HCC less than 4 cm diameter.Radiofrequency has become popular method for treatment hepatocellular carcinoma (HCC) been applied as an alternative primary therapy to resection.We compared outcomes 148 treated RFA (n = 55) those surgically 93).The rate local recurrence among was significantly higher surgery (P 0.005), while incidence remote similar between two...
Current selection criteria of liver transplantation (LT) for patients with hepatocellular carcinoma (HCC) were derived from the outcomes cadaveric donor LT (CDLT). We tried to assess applicability such living (LDLT) through a comparative study between CDLT and LDLT. analyzed 312 HCC who underwent at 4 Korean institutions during 1992 2002. There no gross differences tumor characteristics group (n = 75) LDLT 237). Overall 3-year survival rate (3-YSR) was 61.1% after 73.2% including 38 cases...
The role of the radiofrequency ablation (RFA) in treatment solitary liver metastasis has not been established yet. Both hepatic resection (HR) and RFA have used increasingly colorectal metastases.A systemic review was performed to determine impact modality on recurrence patterns, disease-free survival, overall survival (OS) rates.Solitary metastases were treated by HR 116 patients (75.8%) 37 (24.2%) with RFA. Prognostic factors, rate, rates analyzed. cumulative 3-year 5-year local free...
Purpose To compare radiofrequency (RF) ablation with nonanatomic resection (NAR) as first-line treatment in patients a single Barcelona Clinic Liver Cancer (BCLC) stage 0 or A hepatocellular carcinoma (HCC) and to evaluate the long-term outcomes of both therapies. Materials Methods This retrospective study was approved by institutional review board. The requirement for informed consent waived. Data were reviewed from 580 HCCs measuring 3 cm smaller (BCLC A) who underwent ultrasonographically...
To develop and validate a model to predict tumor recurrence after living donor liver transplantation (LDLT) (MoRAL) for hepatocellular carcinoma (HCC) beyond the Milan criteria (MC).Some subgroups of HCC exceeding MC experience substantial benefit from LDLT.This multicenter study included total 566 consecutive patients who underwent LDLT in Korea: beyond-MC cohort (n = 205, derivation [n 92] validation 113] sets) within-MC 361). The primary endpoint was time-to-recurrence.Using multivariate...
Given the complexity of managing hepatocellular carcinoma (HCC), a multidisciplinary approach (MDT) is recommended to optimize management HCC patients. However, evidence suggesting that MDT improves patient outcome limited.We performed retrospective cohort study all patients newly-diagnosed with between 2005 and 2013 (n = 6,619). The overall survival (OS) rates who were not managed via compared in entire 6,619), exactly matched 1,396).In cohort, 5-year rate was significantly higher (71.2%...
Early allograft dysfunction (EAD) affects outcomes in liver transplantation (LT). Existing risk models developed for deceased-donor LT depend on posttransplant factors and fall short living-donor (LDLT), where pretransplant evaluations are crucial preventing EAD justifying the donor's risks. This retrospective study analyzed data from 2944 adult patients who underwent LDLT at 17 centers between 2016 2020. We a logistic regression model to predict based this development cohort. used 1020 King...
The purpose of this study was to evaluate the diagnostic efficacy three-phase helical dynamic CT in detection and characterization hepatocellular carcinomas dysplastic nodules cirrhotic livers.Three-phase 41 patients with liver cirrhosis evaluated prospectively before orthotopic transplantation. numbers were assessed explanted livers compared pretransplantation findings.Examination revealed 21 15 23 10 patients. size 0.6-5. 0 cm (mean, 1.9 cm), that 0.7-2.0 1.0 cm). use enabled (sensitivity,...
Hepatocellular carcinoma (HCC) is the most common tumor in adult liver, with high relapse and mortality rates despite diverse treatment modalities. In this study, nicotinamide N-methyltransferase (NNMT), a key enzyme drug metabolism, was investigated as potential prognostic factor. Frozen tumors non-cancerous surrounding tissues from 120 patients primary HCC were studied. Expressions of NNMT internal control genes measured by real-time reverse-transcription PCR (RT-PCR). The relationship...
The problem of graft size is one the critical factors limiting expansion adult-to-adult living donor liver transplantation (LDLT). We compared outcome LDLT recipients who received grafts with a graft-to-recipient weight ratio (GRWR) < 0.8% or GRWR > = 0.8%, and we analyzed risk affecting survival after small-for-size (SFSGs) were used. Between June 1997 April 2008, 427 patients underwent right lobe at Department Surgery Samsung Medical Center. Recipients divided into 2 groups: group A (n 35)...
To compare the long-term outcomes of repeated hepatic resection and radiofrequency (RF) ablation for recurrent hepatocellular carcinoma (HCC) by using propensity score matching.This retrospective study was approved institutional review board, requirement to obtain informed consent waived. Thirty-nine patients who underwent 178 RF HCC (mean tumor size ± standard deviation, 1.8 cm 0.7) between November 1994 December 2012 were included in study. Patients ranged age from 24 85 years (mean, 54.9...
Abstract Background The aim of the present study was to compare prognostic impact anatomic resection ( AR ) versus non‐anatomic NAR on patient survival after a single hepatocellular carcinoma HCC ). Methods To control for confounding variable distributions, 1‐to‐1 propensity score match applied outcomes and . Among 710 patients with primary, solitary <5.0 cm in diameter that resectable by either or from 2003 2007 Japan Korea, 355 underwent at least one section complete removal portal...
Even after 2 decades of experience in laparoscopic hepatectomy, data on purely approach for donor hepatectomy adult living liver transplantation (LDLT) are limited. We report our initial a recipients to explore its potential application the management donors. did retrospective analysis 54 consecutive patients operated between May 2013 and February 2015. There were 41 right, 10 extended 3 left hepatectomies. The median operative time was 436 minutes (range 294-684 minutes), warm ischemia 6...
Because of the shortage deceased-donor livers for transplantation, living-donor liver transplantation (LDLT) has become an indispensible treatment strategy end-stage disease. The critical prerequisite LDLT is maximal safety healthy donors.From June 1996 to November 2010, a total 827 completed donor hepatectomies were performed in our center. We analyzed morbidity associated with LDLT.There was no mortality. No complications observed 744 (90.0%) donors, and 83 (10.0%) donors experienced...
Living-donor liver transplantation (LDLT) is becoming an important tool in hepatocellular carcinoma (HCC) treatment. However, the oncologic outcome between LDLT and deceased-donor LT (DDLT) for HCC remains controversial. This study aims to compare recurrence rates after versus DDLT.Two hundred sixteen patients (166 LDLTs 50 DDLTs) who underwent within University of California-San Francisco criteria were retrospectively reviewed. divided into two groups: small living-donor graft (LDG;...
To determine whether autotransfusion of red blood cells (RBCs) salvaged during liver transplantation is associated with the recurrence hepatocellular carcinoma (HCC).Blood salvage widely used to reinfuse autologous RBCs and reduce allogeneic transfusion. However, reintroduction cancer via a major concern in HCC patients.Among 397 patients who underwent living-donor for HCC, 97 114 recipients without intraoperative were matched 222 283 unfixed matching ratio using propensity score based on...