A5101397024- Hepatocellular Carcinoma Treatment and Prognosis
- MRI in cancer diagnosis
- Liver Disease Diagnosis and Treatment
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Pancreatic and Hepatic Oncology Research
- Radiomics and Machine Learning in Medical Imaging
- Liver Disease and Transplantation
- Gallbladder and Bile Duct Disorders
- Genetic and Kidney Cyst Diseases
- Renal cell carcinoma treatment
- Advanced MRI Techniques and Applications
- Neuroendocrine Tumor Research Advances
- Antimicrobial Peptides and Activities
- Pancreatitis Pathology and Treatment
- Gastric Cancer Management and Outcomes
- Pediatric Hepatobiliary Diseases and Treatments
- Esophageal and GI Pathology
- Insect Utilization and Effects
- Gastrointestinal disorders and treatments
- Intracranial Aneurysms: Treatment and Complications
- Invertebrate Immune Response Mechanisms
- Colorectal Cancer Surgical Treatments
- Vascular Tumors and Angiosarcomas
- Nonmelanoma Skin Cancer Studies
- Medical Imaging and Pathology Studies
Kyungpook National University
2021-2025
Samsung Medical Center
2015-2024
Sungkyunkwan University
2015-2024
Michigan State University
2024
Rural Development Administration
2018-2021
National Institute of Agricultural Science and Technology
2017-2020
Korea University
2017
Inje University Ilsan Paik Hospital
2008-2016
Yeungnam University
2014-2015
National Academy of Agricultural Science
2013-2014
Objective: This study was performed to determine whether neoadjuvant treatment increases survival in patients with BRPC. Summary Background Data: Despite many promising retrospective data on the effect of for borderline resectable pancreatic cancer (BRPC), no high-level evidence exists support role such treatment. Methods: phase 2/3 multicenter randomized controlled trial designed enroll 110 BRPC who were randomly assigned gemcitabine-based chemoradiation (54 Gray external beam radiation)...
We compared the diagnostic performance of gadoxetic acid-enhanced MRI with that triple-phase 16-, 40-, and 64-MDCT in preoperative detection hepatocellular carcinoma (HCC).Sixty-two consecutively registered patients (54 men, eight women; age range, 31-67 years) 83 HCCs underwent (arterial, portal venous, equilibrium) CT at or 3-T MRI. The diagnosis HCC was established after surgical resection. Three observers independently randomly reviewed MR images on a tumor-by-tumor basis. accuracy these...
Lysophagy eliminates damaged lysosomes and is crucial to cellular homeostasis; however, its underlying mechanisms are not entirely understood. We screen a ubiquitination-related compound library determine that the substrate recognition component of SCF-type E3 ubiquitin ligase complex, SCFFBXO3(FBXO3), which critical lysophagy regulator. Inhibition FBXO3 reduces lysophagic flux in response L-leucyl-L-leucine methyl ester (LLOMe). Furthermore, interacts with TMEM192, leading ubiquitination...
To determine if the combination of gadoxetic acid-enhanced magnetic resonance (MR) imaging and diffusion-weighted (DW) helps to increase accuracy sensitivity in diagnosis small hepatocellular carcinomas (HCCs) compared with those achieved by using each MR technique alone.The institutional review board approved this retrospective study waived requirement for informed consent. The included 130 patients (95 men, 35 women) 179 surgically confirmed HCCs (≤2.0 cm) cirrhosis (90 40 without HCC who...
Object Because of its thin wall, an aneurysm arising from the posterior wall internal carotid artery (ICA), so-called blood blister–like (BBA), is difficult to manage surgically and often associated with high morbidity mortality rates. The authors treated these aneurysms endovascularly. In this paper, they present angiographic clinical results obtained in patients ICA BBAs Methods seven who presented subarachnoid hemorrhage, a total number 12 endovascular treatments were performed, including...
To investigate the imaging features of hypovascular hypointense nodules on hepatobiliary phase gadoxetic acid-enhanced magnetic resonance (MR) images in patients with cirrhosis that may be associated progression to hypervascular hepatocellular carcinoma (HCC).The institutional review board approved this retrospective study and waived informed patient consent. This included 135 a diagnosis hepatitis B-induced liver 214 MR images. were analyzed respect nodule size, degree hypointensity at...
The purpose of this article is to evaluate the value gadoxetic acid-enhanced hepatobiliary phase imaging and high-b-value diffusion-weighted (DWI) for distinguishing well-differentiated hepatocellular carcinomas (HCCs) from benign nodules in patients with chronic liver disease using 3-T MRI.Forty-five 46 HCCs (mean, 2.3 cm) 21 24 (five large regenerative 19 dysplastic nodules; mean, 1.8 were included study. Diagnosis was made histopathologically by percutaneous biopsy (n = 12 n 11,...
To evaluate the added value of diffusion-weighted (DW) imaging in combination with T2-weighted magnetic resonance (MR) compared alone for predicting tumor clearance mesorectal fascia (MRF) after neoadjuvant chemotherapy and radiation therapy (CRT) patients locally advanced rectal cancer.This retrospective study was approved by institutional review board, informed consent waived. Forty-five cancer clinically suspected MRF invasion who underwent CRT subsequent surgery were enrolled. All pre-...
Purpose To determine the preoperative magnetic resonance (MR) imaging findings potentially most useful for predicting cytokeratin 19 (CK19)-positive hepatocellular carcinoma (HCC) and to evaluate prognosis after curative resection in patients with a single HCC lesion positive CK19 compared who are negative CK19. Materials Methods The institutional review board approved this study waived requirement informed consent. Two hundred four CK19-negative 38 CK19-positive underwent gadoxetic...
The purpose of this study was to determine the finding most predictive for characterizing hypervascular hepatocellular carcinoma (HCC) measuring 1 cm or less at gadoxetic acid-enhanced MRI that includes diffusion-weighted images.In retrospective study, between May 2008 and June 2009, 66 patients with 108 HCCs smaller underwent 3-T included images. diagnosis HCC determined by surgical resection in 32 cases, percutaneous biopsy three interval growth larger than on follow-up images accordance...
Given the complexity of managing hepatocellular carcinoma (HCC), a multidisciplinary approach (MDT) is recommended to optimize management HCC patients. However, evidence suggesting that MDT improves patient outcome limited.We performed retrospective cohort study all patients newly-diagnosed with between 2005 and 2013 (n = 6,619). The overall survival (OS) rates who were not managed via compared in entire 6,619), exactly matched 1,396).In cohort, 5-year rate was significantly higher (71.2%...
Purpose: To compare the diagnostic accuracy and sensitivity of combined gadoxetic acid-enhanced magnetic resonance imaging (MRI) diffusion-weighted (DWI) with each approach alone for detecting small hepatic metastases (≤1.5 cm). Materials Methods: Institutional review board approved this retrospective study waived informed patient consent. Eighty-six patients 179 liver underwent MRI including unenhanced DWI at 3.0 T. Three image sets images—gadoxetic acid set (early dynamic hepatocyte...
This study evaluated the significance of cystic fluid analysis and radiologic findings in differential diagnosis biliary cystadenomas (BCA) hepatic simple cysts (HSCs).BCA are premalignant lesions. The treatment choice is surgical excision. It important to differentiate BCA from HSCs because they have different clinical significances plans. However, it difficult preoperatively a HSC.This retrospective was done with 31 patients suffering pathologically diagnosed or HSC. All underwent surgery...
To examine the differential features of combined hepatocellular and cholangiocarcinoma (HCC-CC) from mass-forming intrahepatic (ICC) on gadoxetic acid-enhanced MRI.Forty patients with pathologically proven HCC-CC (n = 20) ICCs who had undergone MRI were enrolled in this study. MR images analyzed for shape lesions, hypo- or hyperintense areas T2-weighted image (T2WI), rim enhancement during early dynamic phases, central hypointense (target appearance) 10-min 20-min hepatobiliary phase (HBP)....
Differentiating Mass-Forming Autoimmune Pancreatitis From Pancreatic Ductal Adenocarcinoma on the Basis of Contrast-Enhanced MRI and DWI FindingsSeo-Youn Choi1, Seong Hyun Kim2, Tae Wook Kang2, Kyoung Doo Song2, Jeong Park3 Yoon-Hyeong Choi4Audio Available | Share Claim CREDIT
Purpose To assess the value of diffusion-weighted (DW) imaging as a prognostic marker in preoperative evaluation patients with mass-forming intrahepatic cholangiocarcinoma (ICC). Materials and Methods This retrospective study was approved by institutional review board, informed consent requirement waived. A total 91 who underwent hepatic resection DW for ICC were included. Two radiologists evaluated degree diffusion restriction tumors using qualitative (visual) interpretation combined...
Tenebrio molitor is a major pest of stored grain, although its larvae have potential for use as food. However, little known about the characteristics individual larval instars this species, and number remains disputed. Therefore, we assessed T. average at different stages. The focus study was to establish foundation further studies on each instar. All showed incubation periods 7 8 d period 3 4 <TEX>$1^{st}$</TEX> Beyond instar, there were relatively large variations in days instar period....
To prospectively evaluate both the correlation between abnormal Doppler ultrasonography (US) hepatic vein waveforms and venous pressure gradient (HVPG) response to drug treatment in patients with cirrhosis.Ethics committee approval informed consent of control subjects were obtained. In 78 cirrhosis (70 men, eight women; mean age, 49.4 years +/- 9.7 [standard deviation]) a history variceal bleeding, waveform--as measured US--and HVPG measured, relationship them was analyzed. Hepatic...
OBJECTIVE Ruptured aneurysms or pseudoaneurysms on the collateral vessels in patients with moyamoya disease have been known to be difficult treat surgically because of their deep location and combined ischemic condition brain. For several years, we treated these by endovascular means. In this article, describe detailed techniques outcomes. METHODS Eight who presented intracerebral intraventricular hemorrhage were embolization. All had small aneurysmal lesions distal arteries (the part...
Parenchyma-preserving resection for the treatment of benign pancreatic neuroendocrine tumors (NETs) has been tried, and preoperative prediction NET is important. Recently, diffusion-weighted imaging (DWI) abdomen magnetic resonance (MRI) used to characterize malignant DWI might be helpful in NETs.To evaluate value gadoxetic acid-enhanced MRI predicting NETs determination parenchyma-preserving resection.Our ethics committee approved this study with a waiver informed consent given its...