- Reproductive Biology and Fertility
- Gastric Cancer Management and Outcomes
- Colorectal Cancer Screening and Detection
- Helicobacter pylori-related gastroenterology studies
- Hepatocellular Carcinoma Treatment and Prognosis
- Reproductive System and Pregnancy
- Eosinophilic Esophagitis
- Endometriosis Research and Treatment
- Sperm and Testicular Function
- Uterine Myomas and Treatments
- Pregnancy and preeclampsia studies
- Reproductive Health and Technologies
- Ovarian function and disorders
- Liver Disease Diagnosis and Treatment
- Birth, Development, and Health
- Gastroesophageal reflux and treatments
- MRI in cancer diagnosis
- Esophageal Cancer Research and Treatment
- Complementary and Alternative Medicine Studies
- Coenzyme Q10 studies and effects
- Colorectal and Anal Carcinomas
- Genetic factors in colorectal cancer
- Adipokines, Inflammation, and Metabolic Diseases
- Colorectal Cancer Surgical Treatments
- Phytoestrogen effects and research
Korea Institute of Public Finance
2016-2024
Shaikh Khalifa Medical City
2020-2021
Samsung Medical Center
2011-2019
National Development Institute of Korean Medicine
2019
Ministry of Health and Welfare
2019
Yonsei University
2013-2019
Severance Hospital
2013-2019
Seoul National University Hospital
2007-2018
Orthopedic Specialty Hospital
2017
Ajou University Hospital
2015
Abstract Background The aim of this study was to evaluate the time trend seropositivity Helicobacter pylori ( H . ) over period 13 years in an asymptomatic Korean population, and investigate associated risk factors. Methods This cross-sectional nationwide multicentre surveyed anti- IgG antibodies 19,272 health check-up subjects (aged [greater than equal to]16 years) 2011. Risk factors for infection were investigated using logistic regression. Seropositivity without eradication compared...
To evaluate the added value of diffusion-weighted (DW) imaging in combination with T2-weighted magnetic resonance (MR) compared alone for predicting tumor clearance mesorectal fascia (MRF) after neoadjuvant chemotherapy and radiation therapy (CRT) patients locally advanced rectal cancer.This retrospective study was approved by institutional review board, informed consent waived. Forty-five cancer clinically suspected MRF invasion who underwent CRT subsequent surgery were enrolled. All pre-...
Colorectal cancer screening is recommended for average-risk persons beginning at age 50. However, information about the incidence and risk factors of precursor adenoma in preceding decades limited. The aim this study was to determine prevalence colorectal aged 40-49 years compare data with those 30-39 50-59 years.A cross-sectional 5254 asymptomatic subjects who underwent colonoscopy conducted. Data were stratified by into three groups: 608 years, 1930 2716 years.Prevalence overall adenomas...
Background: Recent literature has recognized a correlation with depression and poor self-reported functional outcome after orthopaedic procedures. However, the effect of on anterior cruciate ligament reconstruction (ACLR) never been studied. Purpose: To quantify incidence major depressive disorder (MDD) correlate symptoms patient-rated knee function in patients undergoing ACLR. Study Design: Cohort study; Level evidence, 2. Methods: In this multicenter prospective cohort study, 64...
Computed tomography enterography (CTE) has become a main modality for the evaluation of inflammatory bowel disease (IBD). It simultaneously offers visualization small and extraintestinal status, which is helpful diagnosing IBD. Crohn long segmental enhancing wall thickening related with eccentric longitudinal distribution. In addition, mural stratification, fibrofatty proliferation, positive comb sign by increased mesenteric vascularity internal/perianal fistula are characteristics can be...
To evaluate the value of diffusion-weighted (DW) imaging in differentiation an intrapancreatic accessory spleen (IPAS) from a small (<3 cm) solid pancreatic tumor.This retrospective study was approved by institutional review board, and informed consent waived. Twenty patients with IPAS 22 tumors were included. All underwent abdominal magnetic resonance (MR) DW gadoxetic acid-enhanced imaging. Qualitative (signal intensity) quantitative intensity apparent diffusion coefficient [ADC])...
Helicobacter pylori causes numerous extragastric manifestations, including coronary heart disease. The artery calcification (CAC) score, measured using computed tomography (CT) has been used as a screening test for atherosclerosis. This study investigated the association between H. seropositivity and CAC scores in population.Patients who underwent health checkup October 2003 July 2007 did not have history of ischemic disease were enrolled study. Subjects screened with multidetector CT scan...
Background US has served as a standard surveillance tool for hepatocellular carcinoma (HCC); however, the detection rate and false referral with this modality are suboptimal. Purpose To evaluate added value of perfluorobutane-enhanced when combined conventional B-mode an HCC in participants liver cirrhosis. Materials Methods This prospective multi-institution diagnostic trial (https://ClinicalTrials.gov, NCT02188901) used intraindividual comparison design single arm study was conducted at...
Abstract Aims and objectives To explore the factors associated with intention to leave among nurses in small‐ medium‐sized hospitals determine predictors about work environment rewards. Background Compared large hospitals, insight into working conditions, rewards turnover of for these is lacking internationally. Design Cross‐sectional study design. Methods Data were obtained from Korean Nurses Association's 2016 Welfare Policy System Improvement Survey. Of participants, data 951 staff three...
This study aimed to evaluate the protective effect of N-acetyl-L-cysteine (NAC) as an antioxidant on busulfan-induced testicular dysfunction in mice and elucidate its possible mechanism action.Thirty-two C57BL/6 male were randomly divided into four groups (n=8/group) follows: (1) control group (oral administration saline [0.1 mL daily] for 35 days); (2) NAC [10 mg/kg (3) busulfan (double intraperitoneal injections 20 mg/kg; total dose 40 mg/kg); (4) busulfan+NAC (after double mg/kg, days)....
Abstract Aim: The aim of the present study was to examine expression vascular endothelial growth factor (VEGF) and visfatin in third trimester placental bed pregnancies with without preeclampsia (PE). Material Methods: group consisted biopsy tissues obtained from ( n = 20) PE. normotensive controls PE were matched for gestational age at delivery patients VEGF evaluated using reverse transcriptase‐polymerase chain reaction (RT‐PCR), real‐time polymerase (PCR), immunohistochemistry Western...
Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Korea College Seoul, Catholic Health Promotion Center, St. Mary's Ewha Womans School Soonchunhyang Cheonan, Hallym Chonnam Gwangju, Kyungpook Daegu, Chungnam Daejeon, Digestive Research Institute, Wonkwang Iksan, Inje Busan, Yonsei Wonju Wonju, Gachon Gil Medical Incheon, Chungbuk Cheongju, Gangneung Asan Gangneung, Cancer Prevention Korean Ilsan, Kwangju Christian Eulji Kyung Hee SMG-SNU Boramae
To investigate the efficacy of topical 5-aminoimidazole-4-carboxamide-1-β-d-ribofuranoside (AICAR) in a mouse model experimental dry eye (EDE).Eye drops consisting 0.001% or 0.01% AICAR, 0.05% cyclosporine A (CsA), balanced salt solution (BSS) were applied for treatment EDE. Tear volume, tear film break-up time (BUT), and corneal fluorescein staining scores measured 10 days after treatment. Levels interleukin (IL)-1β, IL-6, tumor necrosis factor (TNF)-α, interferon (IFN)-γ, gamma-induced...
This study was aimed to establish the most effective premature ovarian failure (POF) mouse model using Cyclophosphamide (CTX), busulfan (Bu), and cisplatin considering treatment duration of anticancer drugs natural recovery time.POF induced by intraperitoneally injecting CTX (120 mg/kg)/Bu (12 mg/kg) for 1 4 weeks or (2 3 14 days C57BL/6 female mice aged 6 8 weeks. Controls were injected with equal volume saline same periods. Body weight measured every week, uterine weights after last...
Upper extremity fractures account for 71% to 90% of pediatric fractures.1 Among upper fractures, supracondylar humerus are one the most common requiring surgery.2-5 These injuries may be associated with nerve injury (20%), vascular injury, and/or compartment syndrome, and treatment complicated by angular deformities, such as cubitus varus.6-10 The American Academy Orthopaedic Surgeons (AAOS) approved appropriate use criteria (AUC) in an effort assist clinician caring these injuries. Here, we...
This study aimed to evaluate the clinical efficacy of a portable smartphone-based system for computer-assisted semen analysis (CASA) compared with results manual microscopic (SA) and laboratory-based CASA self-evaluation parameters by male partner.From July 2017 February 2018, total 28 samples were analyzed concentration motility those from SA Makler Counting Chamber (SEFI Medical Instruments, Israel).Sperm measured positively correlated microscopic-based results. Likewise, sperm calculated...
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This study aims to analyze the effects of learning competency enhancement programs for diverse university student groups and provide practical implications planning operation support in settings. Data were collected from 194 participants, including students on academic probation, low-achieving students, transition students. Paired t-tests Wilcoxon signed-rank tests used changes before after program participation. The main findings are as follows: First, probation showed an improvement GPA...