A5028862176- Hepatocellular Carcinoma Treatment and Prognosis
- Liver Disease and Transplantation
- Organ Transplantation Techniques and Outcomes
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Liver Disease Diagnosis and Treatment
- Pancreatic and Hepatic Oncology Research
- Gallbladder and Bile Duct Disorders
- Colorectal Cancer Treatments and Studies
- Gastric Cancer Management and Outcomes
- Hepatitis B Virus Studies
- Cancer, Lipids, and Metabolism
- Hepatitis C virus research
- Pediatric Hepatobiliary Diseases and Treatments
- Liver physiology and pathology
- Organ Donation and Transplantation
- Cancer, Hypoxia, and Metabolism
- Renal Transplantation Outcomes and Treatments
- Pancreatitis Pathology and Treatment
- Renal cell carcinoma treatment
- Esophageal and GI Pathology
- Liver Diseases and Immunity
- Transplantation: Methods and Outcomes
- Esophageal Cancer Research and Treatment
- Neuroendocrine Tumor Research Advances
- Nanoplatforms for cancer theranostics
National Center for Global Health and Medicine
2016-2025
Center for Global Health
2017-2025
The University of Tokyo
2014-2024
University of Tokyo Hospital
2008-2022
Japan Breast Cancer Research Group
2011-2022
Japan Cancer Society
2018-2022
The Japanese Society of Gastroenterological Surgery
2016-2021
Keio University
2014-2020
Japanese Foundation For Cancer Research
2020
Japan Surgical Society
2013-2020
The use of laparoscopy for liver surgery is increasing rapidly. Second International Consensus Conference on Laparoscopic Liver Resections (LLR) was held in Morioka, Japan, from October 4 to 6, 2014 evaluate the current status laparoscopic and provide recommendations aid its future development. Seventeen questions were addressed. first 7 focused outcomes that reflect benefits risks LLR. These addressed using Zurich-Danish consensus conference model which literature expert opinion weighed by...
Hepatocellular carcinoma (HCC) is one of the leading causes cancer death not only in Japan but also worldwide. Clinical practice guidelines for HCC were first published 2001 by European Society Study Liver (EASL) followed American Association Disease (AASLD) 2005 and updated 2010. However, these have proven to be somewhat unsuitable Japanese patients. In 2005, supported Ministry Health, Labour Welfare, evidence-based clinical compiled Japan. 2009, a revised version was published. Based on...
Abstract BACKGROUND: We have often encountered difficulties in identifying small liver cancers during surgery. Fluorescent imaging using indocyanine green (ICG) has the potential to detect through visualization of disordered biliary excretion ICG cancer tissues and noncancerous compressed by tumor. METHODS: had been intravenously injected for a routine function test 37 patients with hepatocellular carcinoma (HCC) 12 metastasis colorectal (CRC) before resection. Surgical specimens were...
In Brief Objectives: To evaluate the prognostic impact of anatomic versus nonanatomic resection on patients’ survival after a single hepatocellular carcinoma (HCC). Summary Background Data: Anatomic is reasonable treatment option for HCC; however, its clinical significance remains to be confirmed. Methods: Curative hepatic was performed HCC in 210 patients; patients were classified into (n = 156) and 54) groups. 84 assigned group, segmentectomy or subsegmentectomy performed. We evaluated...
This trial compared the efficacy and safety of transarterial chemoembolisation (TACE) plus sorafenib with TACE alone using a newly established TACE-specific endpoint pre-treatment before initial TACE.Patients unresectable hepatocellular carcinoma (HCC) were randomised to (n=80) or (n=76). Patients in combination group received 400 mg once daily for 2-3 weeks TACE, followed by 800 during on-demand conventional sessions until time untreatable (unTACEable) progression (TTUP), defined as tumour...
Abstract An international panel of multidisciplinary experts convened to develop recommendations for the management patients with liver metastases from colorectal cancer (CRC). The aim was address main issues facing CRC hepatobiliary team (MDT) when managing such and standardize treatment receive in different centers. Based on current evidence, group agreed a number including following: (a) primary is achieving long disease-free survival (DFS) interval following resection; (b) assessment...
The fourth version of Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society Hepatology, according to methodology evidence-based medicine and partly Grading Recommendations Assessment, Development, Evaluation system, which published in October 2017 Japanese. New or recommendations were described, herein, with a special reference surveillance, diagnostic, treatment algorithms.
The aim of this study was to investigate in a retrospective setting the patients' profile and results those undergoing surgery for hepatocellular carcinoma (HCC) high-volume surgical centers throughout world.Whether HCC is suitable approach which subset patients still controversial. EASL/AASLD (European Association Study Liver Disease/American Disease) guidelines, based on Barcelona Clinic Cancer (BCLC) classification, leave little room hepatic resection; inversely, other reports promote its...
The purpose of this study was to evaluate prognostic factors in patients with recurrence after curative resection hepatocellular carcinoma (HCC) and identify selection criteria for repeat resection.Recent studies have demonstrated that hepatectomy is effective treating intrahepatic recurrent HCC selected patients. However, the these not been fully evaluated.From October 1994 December 2000, 334 underwent primary HCC, 67 received a 2nd HCC. survival results were analyzed, determined using 38...
The 3rd version of Clinical Practice Guidelines for Hepatocellular Carcinoma was revised by the Japan Society Hepatology, according to methodology evidence-based medicine, which published in October 2013 Japanese. Here, we briefly describe new or changed recommendations with a special reference two algorithms surveillance, diagnosis, and treatment.
We propose an objective and practical classification system to predict difficulty of different laparoscopic liver resections (LLRs).Surgical is highly subjective not influenced only by surgical factors. Consequently, few series have described the degree LLR or attempted objectively assess difficulty.From a prospectively maintained database between 1995 2015, patients undergoing without simultaneous procedures were selected, divided into 3 groups according scores based on operative time (<...
In Brief Objective: To evaluate the surgical techniques necessary to complete total laparoscopic segmentectomy (LS) of all liver segments (I–VIII). Background: When compared open surgery, preservation functional hepatic volume may be more difficult during hepatectomy. LS is a possible alternative hemihepatectomy, but anatomically accurate have not yet been well established. Methods: Data 342 consecutive patients who underwent hepatectomy were reviewed. was defined as removal Couinaud's...
The Clinical Practice Guidelines for Hepatocellular Carcinoma (HCC), the first evidence-based guidelines treatment of HCC in Japan, were compiled by an expert panel supported Japanese Ministry Health, Labour, and Welfare. This set covers six research fields: prevention, diagnosis surveillance, surgery, chemotherapy, transarterial chemoembolization, percutaneous local ablation therapy. A systematic review English medical literature on was performed, a total 7192 publications extracted, mainly...
General rules for recording endoscopic findings of esophageal varices were initially proposed in 1980 and revised 1991. These have widely been used Japan other countries. Recently, portal hypertensive gastropathy has recognized as a distinct histological functional entity. Endoscopic ultrasonography can clearly depict vascular structures around the wall patients with hypertension. Owing to progress medicine, we updated slightly modified former rules. The are simpler more straightforward than...
<b><i>Background/Aim:</i></b> Recently, albumin-bilirubin (ALBI) scoring/grading, consisting of only albumin and total bilirubin, has been proposed. We examined the efficacy this grading system for determining hepatic function in patients with hepatocellular carcinoma (HCC). <b><i>Methods/Materials:</i></b> The prognoses 46,681 HCC based on results obtained from a nationwide survey conducted Japan 2001 to 2007 were evaluated using (1)...